RGT2 (YDL138W)


Gene profile

Gene name: RGT2
Reference locus (S288C): YDL138W
Gene biotype: protein_coding

Description: Mfs transporter, sp family, sugar:h+ symporter; High-affinity glucose transporter RGT2; Plasma membrane high glucose sensor that regulates glucose transport; low affinity sesnor that contains 12 predicted transmembrane segments and a long C-terminal tail required for hexose transporter induction; phosphorylation of the tail by Yck1p/Yck2p facilitates binding to the HXT co-repressors, Mth1p and Std1p; RGT2 has a paralog, SNF3, that arose from the whole genome duplication

Top 10 interactors (score): SNF1 (0.964); STD1 (0.955); HXK2 (0.948); GPR1 (0.946); YCK1 (0.945); RGT1 (0.945); HXK1 (0.932); GLK1 (0.927); SNF3 (0.902); MIG1 (0.89); MTH1 (0.86); GPA2 (0.819); CYC8 (0.816); YCK2 (0.788); GRR1 (0.775); SSY1 (0.767); MIG2 (0.712); TUP1 (0.709); GLC7 (0.708); YLR446W (0.695)

Homologues (species, bitscore): SLC2A2 (Homo sapiens, 168.3); Slc2a2 (Mus musculus, 171.4); slc2a1a (Danio rerio, 169.1); slc2a3 (Xenopus tropicalis, 179.1); CG10960 (Drosophila melanogaster, 157.9); hmit-1.3 (Caenorhabditis elegans, 157.5); STP9 (Arabidopsis thaliana, 204.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:197806-200097:+ gene-YDL138W_AKU4011 rna-NM_001180198.1_AKU4011 cds-NP_010143.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:349667-351958:- gene-YDL138W_BG1 rna-NM_001180198.1_BG1 cds-NP_010143.1_BG1 99.3 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:214071-216362:+ gene-YDL138W_Bruggeman rna-NM_001180198.1_Bruggeman cds-NP_010143.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:212138-214429:+ gene-YDL138W_CAT1 rna-NM_001180198.1_CAT1 cds-NP_010143.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:195757-198048:+ gene-YDL138W_CBS1585 rna-NM_001180198.1_CBS1585 cds-NP_010143.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:212746-215037:+ gene-YDL138W_CBS436 rna-NM_001180198.1_CBS436 cds-NP_010143.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:195059-197350:+ gene-YDL138W_CBS6412 rna-NM_001180198.1_CBS6412 cds-NP_010143.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:214228-216519:+ gene-YDL138W_CBS6413 rna-NM_001180198.1_CBS6413 cds-NP_010143.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:212001-214292:+ gene-YDL138W_CENPK1137D rna-NM_001180198.1_CENPK1137D cds-NP_010143.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:209024-211315:+ gene-YDL138W_EthanolRed rna-NM_001180198.1_EthanolRed cds-NP_010143.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:214556-216847:+ gene-YDL138W_FaliES1 rna-NM_001180198.1_FaliES1 cds-NP_010143.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000032.1:2699-4990:- gene-YDL138W_JAY291 rna-NM_001180198.1_JAY291 cds-NP_010143.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:212926-215217:+ gene-YDL138W_MUCL30387 rna-NM_001180198.1_MUCL30387 cds-NP_010143.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:203793-206084:+ gene-YDL138W_MUCL30388 rna-NM_001180198.1_MUCL30388 cds-NP_010143.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:196923-199214:+ gene-YDL138W_MUCL39482 rna-NM_001180198.1_MUCL39482 cds-NP_010143.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe MBVV01000205.1:2655-4946:- gene-YDL138W_MUCL42920 rna-NM_001180198.1_MUCL42920 cds-NP_010143.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:213274-215565:+ gene-YDL138W_NCIM3186 rna-NM_001180198.1_NCIM3186 cds-NP_010143.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:196892-199183:+ gene-YDL138W_NCYC1407 rna-NM_001180198.1_NCYC1407 cds-NP_010143.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:204170-206461:+ gene-YDL138W_PE2H3 rna-NM_001180198.1_PE2H3 cds-NP_010143.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:204174-206465:+ gene-YDL138W_PE2H4 rna-NM_001180198.1_PE2H4 cds-NP_010143.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:213351-215642:+ gene-YDL138W_S288C rna-NM_001180198.1_S288C cds-NP_010143.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000043.1:78916-81207:+ gene-YDL138W_SA1 rna-NM_001180198.1_SA1 cds-NP_010143.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:214317-216608:+ gene-YDL138W_ThermosaccDry rna-NM_001180198.1_ThermosaccDry cds-NP_010143.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:215128-217419:+ gene-YDL138W_VR1 rna-NM_001180198.1_VR1 cds-NP_010143.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:212436-214727:+ gene-YDL138W_ZTW1 rna-NM_001180198.1_ZTW1 cds-NP_010143.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:214483-216771:+ gene-YDL138W_Sparadoxus rna-NM_001180198.1_Sparadoxus cds-NP_010143.1_Sparadoxus 87.9 99.8 Verified 1 1 0 False False False True False

Additional files