Gene name: RGM1
Reference locus (S288C): YMR182C
Gene biotype: protein_coding
Description: Probable transcription repressor protein RGM1; Putative zinc finger DNA binding transcription factor; contains two N-terminal C2H2 zinc fingers and C-terminal proline rich domain; overproduction impairs cell growth and induces expression of genes involved in monosaccharide catabolism and aldehyde metabolism; regulates expression of of Y' telomeric elements and subtelomeric COS genes; relocalizes to the cytosol in response to hypoxia; RGM1 has a paralog, USV1, that arose from the whole genome duplication
Top 10 interactors (score): PHD1 (0.735); ECM22 (0.692); TEC1 (0.657); CBF1 (0.647); SMP1 (0.638); STE12 (0.636); MDG1 (0.633); SCH9 (0.625); MBP1 (0.625); NDT80 (0.621); NRG1 (0.616); GAT3 (0.603); MAL13 (0.571); YAP5 (0.565); SLT2 (0.556); SOK2 (0.538); NHP6B (0.536); TUP1 (0.523); VPS55 (0.521); GIS1 (0.508)
Homologues (species, bitscore): EGR1 (Homo sapiens, 64.3); Egr1 (Mus musculus, 64.3); znf148 (Danio rerio, 63.5); egr1 (Xenopus tropicalis, 63.9); sr (Drosophila melanogaster, 65.1); egrh-1 (Caenorhabditis elegans, 61.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:664474-665109:- | gene-YMR182C_AKU4011 | rna-NM_001182688.1_AKU4011 | cds-NP_013907.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000068.1:8026-8661:+ | gene-YMR182C_BG1 | rna-NM_001182688.1_BG1 | cds-NP_013907.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:608710-609345:- | gene-YMR182C_Bruggeman | rna-NM_001182688.1_Bruggeman | cds-NP_013907.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:611446-612081:- | gene-YMR182C_CAT1 | rna-NM_001182688.1_CAT1 | cds-NP_013907.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:596742-597377:- | gene-YMR182C_CBS1585 | rna-NM_001182688.1_CBS1585 | cds-NP_013907.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:600985-601620:- | gene-YMR182C_CBS436 | rna-NM_001182688.1_CBS436 | cds-NP_013907.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | MBVQ01000065.1:2361-2996:- | gene-YMR182C_CBS6412 | rna-NM_001182688.1_CBS6412 | cds-NP_013907.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:595882-596517:- | gene-YMR182C_CBS6413 | rna-NM_001182688.1_CBS6413 | cds-NP_013907.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:619078-619713:- | gene-YMR182C_CENPK1137D | rna-NM_001182688.1_CENPK1137D | cds-NP_013907.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:657104-657739:- | gene-YMR182C_EthanolRed | rna-NM_001182688.1_EthanolRed | cds-NP_013907.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:602042-602677:- | gene-YMR182C_FaliES1 | rna-NM_001182688.1_FaliES1 | cds-NP_013907.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000265.1:7852-8487:+ | gene-YMR182C_JAY291 | rna-NM_001182688.1_JAY291 | cds-NP_013907.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:602256-602891:- | gene-YMR182C_MUCL30387 | rna-NM_001182688.1_MUCL30387 | cds-NP_013907.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:609036-609671:- | gene-YMR182C_MUCL30388 | rna-NM_001182688.1_MUCL30388 | cds-NP_013907.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:597792-598427:- | gene-YMR182C_MUCL39482 | rna-NM_001182688.1_MUCL39482 | cds-NP_013907.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:605155-605790:- | gene-YMR182C_MUCL42920 | rna-NM_001182688.1_MUCL42920 | cds-NP_013907.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:624486-625121:- | gene-YMR182C_NCIM3186 | rna-NM_001182688.1_NCIM3186 | cds-NP_013907.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:597448-598083:- | gene-YMR182C_NCYC1407 | rna-NM_001182688.1_NCYC1407 | cds-NP_013907.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:607321-607956:- | gene-YMR182C_PE2H3 | rna-NM_001182688.1_PE2H3 | cds-NP_013907.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:608307-608942:- | gene-YMR182C_PE2H4 | rna-NM_001182688.1_PE2H4 | cds-NP_013907.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:624532-625167:- | gene-YMR182C_S288C | rna-NM_001182688.1_S288C | cds-NP_013907.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:182948-183583:+ | gene-YMR182C_SA1 | rna-NM_001182688.1_SA1 | cds-NP_013907.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:598699-599334:- | gene-YMR182C_ThermosaccDry | rna-NM_001182688.1_ThermosaccDry | cds-NP_013907.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:611871-612506:- | gene-YMR182C_VR1 | rna-NM_001182688.1_VR1 | cds-NP_013907.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:14487-15122:- | gene-YMR182C_ZTW1 | rna-NM_001182688.1_ZTW1 | cds-NP_013907.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:616649-617287:- | gene-YMR182C_Sparadoxus | rna-NM_001182688.1_Sparadoxus | cds-NP_013907.1_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |