RGA2 (YDR379W)


Gene profile

Gene name: RGA2
Reference locus (S288C): YDR379W
Gene biotype: protein_coding

Description: GTPase-activating protein for polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p; RGA2 has a paralog, RGA1, that arose from the whole genome duplication

Top 10 interactors (score): CDC24 (0.998); CDC42 (0.998); YAK1 (0.987); RGA1 (0.927); BEM1 (0.921); RSR1 (0.871); CDC28 (0.858); CLA4 (0.854); RHO1 (0.848); BNI1 (0.823); RHO4 (0.817); PXL1 (0.815); BEM2 (0.803); BUD14 (0.798); ACT1 (0.792); EXO84 (0.766); PSY2 (0.761); KNS1 (0.756); STE20 (0.745); SAC6 (0.744)

Homologues (species, bitscore): ARHGAP15 (Homo sapiens, 101.7); Arhgap15 (Mus musculus, 101.3); arhgap12b (Danio rerio, 109.8); arhgap27 (Xenopus tropicalis, 110.5); CdGAPr (Drosophila melanogaster, 90.9); tag-325 (Caenorhabditis elegans, 97.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:565560-568589:+ gene-YDR379W_AKU4011 rna-NM_001180687.1_AKU4011 cds-NP_010667.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000039.1:48859-51888:+ gene-YDR379W_BG1 rna-NM_001180687.1_BG1 cds-NP_010667.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1200943-1203972:+ gene-YDR379W_Bruggeman rna-NM_001180687.1_Bruggeman cds-NP_010667.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1179551-1182580:+ gene-YDR379W_CAT1 rna-NM_001180687.1_CAT1 cds-NP_010667.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1165052-1168081:+ gene-YDR379W_CBS1585 rna-NM_001180687.1_CBS1585 cds-NP_010667.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1183604-1186633:+ gene-YDR379W_CBS436 rna-NM_001180687.1_CBS436 cds-NP_010667.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1161289-1164318:+ gene-YDR379W_CBS6412 rna-NM_001180687.1_CBS6412 cds-NP_010667.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1183179-1186208:+ gene-YDR379W_CBS6413 rna-NM_001180687.1_CBS6413 cds-NP_010667.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1228819-1231848:+ gene-YDR379W_CENPK1137D rna-NM_001180687.1_CENPK1137D cds-NP_010667.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1174707-1177736:+ gene-YDR379W_EthanolRed rna-NM_001180687.1_EthanolRed cds-NP_010667.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1177994-1181023:+ gene-YDR379W_FaliES1 rna-NM_001180687.1_FaliES1 cds-NP_010667.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000057.1:10057-13086:- gene-YDR379W_JAY291 rna-NM_001180687.1_JAY291 cds-NP_010667.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1184262-1187291:+ gene-YDR379W_MUCL30387 rna-NM_001180687.1_MUCL30387 cds-NP_010667.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1166870-1169899:+ gene-YDR379W_MUCL30388 rna-NM_001180687.1_MUCL30388 cds-NP_010667.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1156603-1159632:+ gene-YDR379W_MUCL39482 rna-NM_001180687.1_MUCL39482 cds-NP_010667.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1098994-1102023:+ gene-YDR379W_MUCL42920 rna-NM_001180687.1_MUCL42920 cds-NP_010667.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1230090-1233119:+ gene-YDR379W_NCIM3186 rna-NM_001180687.1_NCIM3186 cds-NP_010667.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1170574-1173603:+ gene-YDR379W_NCYC1407 rna-NM_001180687.1_NCYC1407 cds-NP_010667.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1180658-1183687:+ gene-YDR379W_PE2H3 rna-NM_001180687.1_PE2H3 cds-NP_010667.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1186239-1189268:+ gene-YDR379W_PE2H4 rna-NM_001180687.1_PE2H4 cds-NP_010667.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1230167-1233196:+ gene-YDR379W_S288C rna-NM_001180687.1_S288C cds-NP_010667.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000072.1:48940-51969:+ gene-YDR379W_SA1 rna-NM_001180687.1_SA1 cds-NP_010667.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1182275-1185304:+ gene-YDR379W_ThermosaccDry rna-NM_001180687.1_ThermosaccDry cds-NP_010667.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:609618-612647:+ gene-YDR379W_VR1 rna-NM_001180687.1_VR1 cds-NP_010667.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:225103-228133:+ gene-YDR379W_ZTW1 rna-NM_001180687.1_ZTW1 cds-NP_010667.1_ZTW1 99.9 100.0 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1176847-1179876:+ gene-YDR379W_Sparadoxus rna-NM_001180687.1_Sparadoxus cds-NP_010667.1_Sparadoxus 88.2 99.9 Verified 1 1 1 False True False False False

Additional files