Gene name: RGA1
Reference locus (S288C): YOR127W
Gene biotype: protein_coding
Description: GTPase-activating protein for polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; RGA1 has a paralog, RGA2, that arose from the whole genome duplication
Top 10 interactors (score): CDC42 (0.999); CDC24 (0.998); YAK1 (0.987); RSR1 (0.95); CLA4 (0.948); RHO1 (0.935); LRG1 (0.933); GIC2 (0.928); RGA2 (0.927); BNI1 (0.894); BEM1 (0.891); BEM2 (0.874); RHO4 (0.863); NBA1 (0.835); STE20 (0.814); PXL1 (0.814); RDI1 (0.812); CLN2 (0.806); ACT1 (0.799); BUD14 (0.798)
Homologues (species, bitscore): ARHGAP32 (Homo sapiens, 97.1); Arhgap32 (Mus musculus, 97.4); LOC562449 (Danio rerio, 98.6); arhgap12 (Xenopus tropicalis, 101.3); CdGAPr (Drosophila melanogaster, 93.2); pac-1 (Caenorhabditis elegans, 90.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:545235-548258:+ | gene-YOR127W_AKU4011 | rna-NM_001183546.1_AKU4011 | cds-NP_014770.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:31014-34037:- | gene-YOR127W_BG1 | rna-NM_001183546.1_BG1 | cds-NP_014770.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:548780-551803:+ | gene-YOR127W_Bruggeman | rna-NM_001183546.1_Bruggeman | cds-NP_014770.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:548788-551811:+ | gene-YOR127W_CAT1 | rna-NM_001183546.1_CAT1 | cds-NP_014770.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:540797-543820:+ | gene-YOR127W_CBS1585 | rna-NM_001183546.1_CBS1585 | cds-NP_014770.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:545505-548528:+ | gene-YOR127W_CBS436 | rna-NM_001183546.1_CBS436 | cds-NP_014770.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:539283-542306:+ | gene-YOR127W_CBS6412 | rna-NM_001183546.1_CBS6412 | cds-NP_014770.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:546579-549602:+ | gene-YOR127W_CBS6413 | rna-NM_001183546.1_CBS6413 | cds-NP_014770.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:561246-564269:+ | gene-YOR127W_CENPK1137D | rna-NM_001183546.1_CENPK1137D | cds-NP_014770.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:541604-544627:+ | gene-YOR127W_EthanolRed | rna-NM_001183546.1_EthanolRed | cds-NP_014770.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:545300-548323:+ | gene-YOR127W_FaliES1 | rna-NM_001183546.1_FaliES1 | cds-NP_014770.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000063.1:10945-13968:- | gene-YOR127W_JAY291 | rna-NM_001183546.1_JAY291 | cds-NP_014770.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:553338-556361:+ | gene-YOR127W_MUCL30387 | rna-NM_001183546.1_MUCL30387 | cds-NP_014770.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:558545-561568:+ | gene-YOR127W_MUCL30388 | rna-NM_001183546.1_MUCL30388 | cds-NP_014770.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:548192-551215:+ | gene-YOR127W_MUCL39482 | rna-NM_001183546.1_MUCL39482 | cds-NP_014770.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:564238-567261:+ | gene-YOR127W_MUCL42920 | rna-NM_001183546.1_MUCL42920 | cds-NP_014770.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:561059-564082:+ | gene-YOR127W_NCIM3186 | rna-NM_001183546.1_NCIM3186 | cds-NP_014770.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:554639-557662:+ | gene-YOR127W_NCYC1407 | rna-NM_001183546.1_NCYC1407 | cds-NP_014770.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:553642-556665:+ | gene-YOR127W_PE2H3 | rna-NM_001183546.1_PE2H3 | cds-NP_014770.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:564019-567042:+ | gene-YOR127W_PE2H4 | rna-NM_001183546.1_PE2H4 | cds-NP_014770.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:561170-564193:+ | gene-YOR127W_S288C | rna-NM_001183546.1_S288C | cds-NP_014770.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000034.1:90710-93733:+ | gene-YOR127W_SA1 | rna-NM_001183546.1_SA1 | cds-NP_014770.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:544483-547506:+ | gene-YOR127W_ThermosaccDry | rna-NM_001183546.1_ThermosaccDry | cds-NP_014770.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:546585-549608:+ | gene-YOR127W_VR1 | rna-NM_001183546.1_VR1 | cds-NP_014770.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:278419-281442:+ | gene-YOR127W_ZTW1 | rna-NM_001183546.1_ZTW1 | cds-NP_014770.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:550444-553464:+ | gene-YOR127W_Sparadoxus | rna-NM_001183546.1_Sparadoxus | cds-NP_014770.1_Sparadoxus | 86.9 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |