Gene name: RFX1
Reference locus (S288C): YLR176C
Gene biotype: protein_coding
Description: RFX-like DNA-binding protein RFX1; Major transcriptional repressor of DNA-damage-regulated genes; recruits repressors Tup1p and Cyc8p to their promoters; involved in DNA damage and replication checkpoint pathway; similar to a family of mammalian DNA binding RFX1-4 proteins
Top 10 interactors (score): DUN1 (0.964); CYC8 (0.952); MEC1 (0.885); TUP1 (0.878); REB1 (0.87); HDA1 (0.809); RSC3 (0.8); RAD53 (0.799); RNR2 (0.797); SKO1 (0.797); RSC2 (0.791); MOT1 (0.769); ISW1 (0.738); ITC1 (0.723); RNR3 (0.713); RNR4 (0.711); RNR1 (0.709); HUG1 (0.699); DIF1 (0.698); FSH3 (0.698)
Homologues (species, bitscore): RFX2 (Homo sapiens, 94.7); Rfx3 (Mus musculus, 89.4); rfx1b (Danio rerio, 89.0); rfx2 (Xenopus tropicalis, 96.3); Rfx (Drosophila melanogaster, 79.7); daf-19 (Caenorhabditis elegans, 85.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:461909-464344:- | gene-YLR176C_AKU4011 | rna-NM_001182063.1_AKU4011 | cds-NP_013277.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000177.1:19141-21575:- | gene-YLR176C_BG1 | rna-NM_001182063.1_BG1 | cds-NP_013277.1_BG1 | 98.8 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:502253-504687:- | gene-YLR176C_Bruggeman | rna-NM_001182063.1_Bruggeman | cds-NP_013277.1_Bruggeman | 99.5 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:501784-504218:- | gene-YLR176C_CAT1 | rna-NM_001182063.1_CAT1 | cds-NP_013277.1_CAT1 | 99.3 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:497406-499841:- | gene-YLR176C_CBS1585 | rna-NM_001182063.1_CBS1585 | cds-NP_013277.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:487549-489983:- | gene-YLR176C_CBS436 | rna-NM_001182063.1_CBS436 | cds-NP_013277.1_CBS436 | 98.8 | 99.9 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:465977-468412:- | gene-YLR176C_CBS6412 | rna-NM_001182063.1_CBS6412 | cds-NP_013277.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:497712-500147:- | gene-YLR176C_CBS6413 | rna-NM_001182063.1_CBS6413 | cds-NP_013277.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:492527-494961:- | gene-YLR176C_CENPK1137D | rna-NM_001182063.1_CENPK1137D | cds-NP_013277.1_CENPK1137D | 99.5 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:461430-463865:- | gene-YLR176C_EthanolRed | rna-NM_001182063.1_EthanolRed | cds-NP_013277.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:490357-492792:- | gene-YLR176C_FaliES1 | rna-NM_001182063.1_FaliES1 | cds-NP_013277.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000004.1:17294-19729:- | gene-YLR176C_JAY291 | rna-NM_001182063.1_JAY291 | cds-NP_013277.1_JAY291 | 98.8 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:502274-504708:- | gene-YLR176C_MUCL30387 | rna-NM_001182063.1_MUCL30387 | cds-NP_013277.1_MUCL30387 | 99.5 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:507206-509640:- | gene-YLR176C_MUCL30388 | rna-NM_001182063.1_MUCL30388 | cds-NP_013277.1_MUCL30388 | 99.5 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:498403-500838:- | gene-YLR176C_MUCL39482 | rna-NM_001182063.1_MUCL39482 | cds-NP_013277.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:498978-501412:- | gene-YLR176C_MUCL42920 | rna-NM_001182063.1_MUCL42920 | cds-NP_013277.1_MUCL42920 | 99.5 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:507771-510206:- | gene-YLR176C_NCIM3186 | rna-NM_001182063.1_NCIM3186 | cds-NP_013277.1_NCIM3186 | 95.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:490827-493262:- | gene-YLR176C_NCYC1407 | rna-NM_001182063.1_NCYC1407 | cds-NP_013277.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:495081-497515:- | gene-YLR176C_PE2H3 | rna-NM_001182063.1_PE2H3 | cds-NP_013277.1_PE2H3 | 98.8 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:494825-497259:- | gene-YLR176C_PE2H4 | rna-NM_001182063.1_PE2H4 | cds-NP_013277.1_PE2H4 | 98.8 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:507797-510232:- | gene-YLR176C_S288C | rna-NM_001182063.1_S288C | cds-NP_013277.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000042.1:17352-19786:- | gene-YLR176C_SA1 | rna-NM_001182063.1_SA1 | cds-NP_013277.1_SA1 | 98.8 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:492881-495316:- | gene-YLR176C_ThermosaccDry | rna-NM_001182063.1_ThermosaccDry | cds-NP_013277.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:504194-506628:- | gene-YLR176C_VR1 | rna-NM_001182063.1_VR1 | cds-NP_013277.1_VR1 | 98.8 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:17251-19685:- | gene-YLR176C_ZTW1 | rna-NM_001182063.1_ZTW1 | cds-NP_013277.1_ZTW1 | 99.5 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:478936-481369:- | gene-YLR176C_Sparadoxus | rna-NM_001182063.1_Sparadoxus | cds-NP_013277.1_Sparadoxus | 88.4 | 99.7 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |