Gene name: RFT1
Reference locus (S288C): YBL020W
Gene biotype: protein_coding
Description: Membrane protein required for translocation of Man5GlcNac2-PP-Dol; required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase; mutation is suppressed by expression of human p53 protein; essential gene
Top 10 interactors (score): ALG11 (0.978); ALG2 (0.936); KRE2 (0.9); ALG13 (0.862); SEC53 (0.726); GPI12 (0.719); URA5 (0.714); ALG7 (0.638); CWH41 (0.577); PMI40 (0.573); YIL067C (0.567); UIP5 (0.567); YIP1 (0.537); OST2 (0.52); ALG1 (0.504); URA10 (0.504); RTG2 (0.502); RTS1 (0.49); COP1 (0.489); DPH2 (0.476)
Homologues (species, bitscore): RFT1 (Homo sapiens, 142.9); Rft1 (Mus musculus, 136.0); rft1 (Danio rerio, 131.7); rft1 (Xenopus tropicalis, 141.0); CG3149 (Drosophila melanogaster, 100.5); ZK180.3 (Caenorhabditis elegans, 71.2); AT5G07630 (Arabidopsis thaliana, 154.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:176011-177735:+ | gene-YBL020W_AKU4011 | rna-NM_001178260.1_AKU4011 | cds-NP_009533.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:166839-168563:+ | gene-YBL020W_BG1 | rna-NM_001178260.1_BG1 | cds-NP_009533.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:176597-178321:+ | gene-YBL020W_Bruggeman | rna-NM_001178260.1_Bruggeman | cds-NP_009533.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:179208-180932:+ | gene-YBL020W_CAT1 | rna-NM_001178260.1_CAT1 | cds-NP_009533.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:168566-170290:+ | gene-YBL020W_CBS1585 | rna-NM_001178260.1_CBS1585 | cds-NP_009533.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:177021-178745:+ | gene-YBL020W_CBS436 | rna-NM_001178260.1_CBS436 | cds-NP_009533.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:267345-269069:+ | gene-YBL020W_CBS6412 | rna-NM_001178260.1_CBS6412 | cds-NP_009533.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:174136-175860:+ | gene-YBL020W_CBS6413 | rna-NM_001178260.1_CBS6413 | cds-NP_009533.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:176166-177890:+ | gene-YBL020W_CENPK1137D | rna-NM_001178260.1_CENPK1137D | cds-NP_009533.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:303553-305277:+ | gene-YBL020W_EthanolRed | rna-NM_001178260.1_EthanolRed | cds-NP_009533.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:190819-192543:+ | gene-YBL020W_FaliES1 | rna-NM_001178260.1_FaliES1 | cds-NP_009533.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000421.1:16490-18214:+ | gene-YBL020W_JAY291 | rna-NM_001178260.1_JAY291 | cds-NP_009533.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:176454-178178:+ | gene-YBL020W_MUCL30387 | rna-NM_001178260.1_MUCL30387 | cds-NP_009533.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:177496-179220:+ | gene-YBL020W_MUCL30388 | rna-NM_001178260.1_MUCL30388 | cds-NP_009533.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:168751-170475:+ | gene-YBL020W_MUCL39482 | rna-NM_001178260.1_MUCL39482 | cds-NP_009533.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:176026-177750:+ | gene-YBL020W_MUCL42920 | rna-NM_001178260.1_MUCL42920 | cds-NP_009533.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:182198-183922:+ | gene-YBL020W_NCIM3186 | rna-NM_001178260.1_NCIM3186 | cds-NP_009533.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:169900-171624:+ | gene-YBL020W_NCYC1407 | rna-NM_001178260.1_NCYC1407 | cds-NP_009533.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:176127-177851:+ | gene-YBL020W_PE2H3 | rna-NM_001178260.1_PE2H3 | cds-NP_009533.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:173771-175495:+ | gene-YBL020W_PE2H4 | rna-NM_001178260.1_PE2H4 | cds-NP_009533.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:182401-184125:+ | gene-YBL020W_S288C | rna-NM_001178260.1_S288C | cds-NP_009533.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000051.1:67122-68846:+ | gene-YBL020W_SA1 | rna-NM_001178260.1_SA1 | cds-NP_009533.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:190774-192498:+ | gene-YBL020W_ThermosaccDry | rna-NM_001178260.1_ThermosaccDry | cds-NP_009533.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:172940-174664:+ | gene-YBL020W_VR1 | rna-NM_001178260.1_VR1 | cds-NP_009533.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:167486-169210:+ | gene-YBL020W_ZTW1 | rna-NM_001178260.1_ZTW1 | cds-NP_009533.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:202425-204149:+ | gene-YBL020W_Sparadoxus | rna-NM_001178260.1_Sparadoxus | cds-NP_009533.1_Sparadoxus | 90.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |