Gene name: RFC4
Reference locus (S288C): YOL094C
Gene biotype: protein_coding
Description: Subunit of heteropentameric Replication factor C (RF-C); which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): RFC2 (0.999); POL30 (0.999); RFC5 (0.999); ELG1 (0.999); RAD24 (0.999); RFC3 (0.999); RFC1 (0.999); CTF18 (0.995); RAD17 (0.991); RFA2 (0.989); MCM7 (0.988); POL12 (0.986); RFA1 (0.986); PRI1 (0.985); PRI2 (0.98); MCM5 (0.98); POL31 (0.973); MCM2 (0.973); POL3 (0.972); MCM4 (0.965)
Homologues (species, bitscore): RFC2 (Homo sapiens, 408.3); Rfc2 (Mus musculus, 406.0); rfc2 (Danio rerio, 407.5); rfc2 (Xenopus tropicalis, 360.5); RfC4 (Drosophila melanogaster, 387.1); rfc-2 (Caenorhabditis elegans, 365.5); RFC2 (Arabidopsis thaliana, 408.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:124903-125874:- | gene-YOL094C_AKU4011 | rna-NM_001183348.1_AKU4011 | cds-NP_014547.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:90012-90983:- | gene-YOL094C_BG1 | rna-NM_001183348.1_BG1 | cds-NP_014547.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:126479-127450:- | gene-YOL094C_Bruggeman | rna-NM_001183348.1_Bruggeman | cds-NP_014547.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:125360-126331:- | gene-YOL094C_CAT1 | rna-NM_001183348.1_CAT1 | cds-NP_014547.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:119342-120313:- | gene-YOL094C_CBS1585 | rna-NM_001183348.1_CBS1585 | cds-NP_014547.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:124618-125589:- | gene-YOL094C_CBS436 | rna-NM_001183348.1_CBS436 | cds-NP_014547.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:119504-120475:- | gene-YOL094C_CBS6412 | rna-NM_001183348.1_CBS6412 | cds-NP_014547.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:126205-127176:- | gene-YOL094C_CBS6413 | rna-NM_001183348.1_CBS6413 | cds-NP_014547.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:135550-136521:- | gene-YOL094C_CENPK1137D | rna-NM_001183348.1_CENPK1137D | cds-NP_014547.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:122503-123474:- | gene-YOL094C_EthanolRed | rna-NM_001183348.1_EthanolRed | cds-NP_014547.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:124830-125801:- | gene-YOL094C_FaliES1 | rna-NM_001183348.1_FaliES1 | cds-NP_014547.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000160.1:17668-18639:+ | gene-YOL094C_JAY291 | rna-NM_001183348.1_JAY291 | cds-NP_014547.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:130682-131653:- | gene-YOL094C_MUCL30387 | rna-NM_001183348.1_MUCL30387 | cds-NP_014547.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:133864-134835:- | gene-YOL094C_MUCL30388 | rna-NM_001183348.1_MUCL30388 | cds-NP_014547.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:127263-128234:- | gene-YOL094C_MUCL39482 | rna-NM_001183348.1_MUCL39482 | cds-NP_014547.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:143033-144004:- | gene-YOL094C_MUCL42920 | rna-NM_001183348.1_MUCL42920 | cds-NP_014547.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:141473-142444:- | gene-YOL094C_NCIM3186 | rna-NM_001183348.1_NCIM3186 | cds-NP_014547.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:133860-134831:- | gene-YOL094C_NCYC1407 | rna-NM_001183348.1_NCYC1407 | cds-NP_014547.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:117157-118128:- | gene-YOL094C_PE2H3 | rna-NM_001183348.1_PE2H3 | cds-NP_014547.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:128137-129108:- | gene-YOL094C_PE2H4 | rna-NM_001183348.1_PE2H4 | cds-NP_014547.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:141584-142555:- | gene-YOL094C_S288C | rna-NM_001183348.1_S288C | cds-NP_014547.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:109465-110436:- | gene-YOL094C_SA1 | rna-NM_001183348.1_SA1 | cds-NP_014547.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:123838-124809:- | gene-YOL094C_ThermosaccDry | rna-NM_001183348.1_ThermosaccDry | cds-NP_014547.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:124406-125377:- | gene-YOL094C_VR1 | rna-NM_001183348.1_VR1 | cds-NP_014547.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:123537-124508:- | gene-YOL094C_ZTW1 | rna-NM_001183348.1_ZTW1 | cds-NP_014547.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:126984-127955:- | gene-YOL094C_Sparadoxus | rna-NM_001183348.1_Sparadoxus | cds-NP_014547.1_Sparadoxus | 92.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |