RFC3 (YNL290W)


Gene profile

Gene name: RFC3
Reference locus (S288C): YNL290W
Gene biotype: protein_coding

Description: Subunit of heteropentameric Replication factor C (RF-C); which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon; relocalizes to the cytosol in response to hypoxia

Top 10 interactors (score): RFC4 (0.999); RFC1 (0.999); RFC2 (0.999); RFC5 (0.999); POL30 (0.999); ELG1 (0.999); CTF18 (0.999); RAD24 (0.999); DCC1 (0.995); POL12 (0.99); MCM3 (0.989); POL1 (0.986); PRI2 (0.983); MCM6 (0.982); MCM7 (0.982); MCM4 (0.982); RFA1 (0.978); MCM2 (0.978); PRI1 (0.978); POL3 (0.976)

Homologues (species, bitscore): RFC5 (Homo sapiens, 345.5); Rfc5 (Mus musculus, 338.2); rfc5 (Danio rerio, 342.4); rfc5 (Xenopus tropicalis, 342.0); RfC3 (Drosophila melanogaster, 309.7); F44B9.8 (Caenorhabditis elegans, 297.4); EMB2810 (Arabidopsis thaliana, 312.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:80036-81058:+ gene-YNL290W_AKU4011 rna-NM_001183128.1_AKU4011 cds-NP_014109.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000074.1:9591-10613:- gene-YNL290W_BG1 rna-NM_001183128.1_BG1 cds-NP_014109.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:89379-90401:+ gene-YNL290W_Bruggeman rna-NM_001183128.1_Bruggeman cds-NP_014109.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:91984-93006:+ gene-YNL290W_CAT1 rna-NM_001183128.1_CAT1 cds-NP_014109.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:80366-81388:+ gene-YNL290W_CBS1585 rna-NM_001183128.1_CBS1585 cds-NP_014109.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:80852-81874:+ gene-YNL290W_CBS436 rna-NM_001183128.1_CBS436 cds-NP_014109.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:77023-78045:+ gene-YNL290W_CBS6412 rna-NM_001183128.1_CBS6412 cds-NP_014109.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:77214-78236:+ gene-YNL290W_CBS6413 rna-NM_001183128.1_CBS6413 cds-NP_014109.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:80051-81073:+ gene-YNL290W_CENPK1137D rna-NM_001183128.1_CENPK1137D cds-NP_014109.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:77052-78074:+ gene-YNL290W_EthanolRed rna-NM_001183128.1_EthanolRed cds-NP_014109.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:77951-78973:+ gene-YNL290W_FaliES1 rna-NM_001183128.1_FaliES1 cds-NP_014109.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000171.1:9245-10267:- gene-YNL290W_JAY291 rna-NM_001183128.1_JAY291 cds-NP_014109.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:89877-90899:+ gene-YNL290W_MUCL30387 rna-NM_001183128.1_MUCL30387 cds-NP_014109.1_MUCL30387 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:82659-83681:+ gene-YNL290W_MUCL30388 rna-NM_001183128.1_MUCL30388 cds-NP_014109.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:78000-79022:+ gene-YNL290W_MUCL39482 rna-NM_001183128.1_MUCL39482 cds-NP_014109.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:79688-80710:+ gene-YNL290W_MUCL42920 rna-NM_001183128.1_MUCL42920 cds-NP_014109.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:86187-87209:+ gene-YNL290W_NCIM3186 rna-NM_001183128.1_NCIM3186 cds-NP_014109.1_NCIM3186 99.9 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:79332-80354:+ gene-YNL290W_NCYC1407 rna-NM_001183128.1_NCYC1407 cds-NP_014109.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:76528-77550:+ gene-YNL290W_PE2H3 rna-NM_001183128.1_PE2H3 cds-NP_014109.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:75916-76938:+ gene-YNL290W_PE2H4 rna-NM_001183128.1_PE2H4 cds-NP_014109.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:86218-87240:+ gene-YNL290W_S288C rna-NM_001183128.1_S288C cds-NP_014109.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000052.1:9977-10999:- gene-YNL290W_SA1 rna-NM_001183128.1_SA1 cds-NP_014109.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:78808-79830:+ gene-YNL290W_ThermosaccDry rna-NM_001183128.1_ThermosaccDry cds-NP_014109.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:91347-92369:+ gene-YNL290W_VR1 rna-NM_001183128.1_VR1 cds-NP_014109.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000029.1:70019-71041:+ gene-YNL290W_ZTW1 rna-NM_001183128.1_ZTW1 cds-NP_014109.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:88088-89110:+ gene-YNL290W_Sparadoxus rna-NM_001183128.1_Sparadoxus cds-NP_014109.1_Sparadoxus 90.3 99.9 Verified 1 1 1 False True False False False

Additional files