Gene name: RFC1
Reference locus (S288C): YOR217W
Gene biotype: protein_coding
Description: Subunit of heteropentameric Replication factor C (RF-C); RF-C is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon; Belongs to the activator 1 large subunit family
Top 10 interactors (score): RFC3 (0.999); POL30 (0.999); RFC5 (0.999); RFC2 (0.999); RFC4 (0.999); POL1 (0.992); RAD24 (0.989); POL2 (0.981); ELG1 (0.974); TOP1 (0.972); POL12 (0.949); CTF18 (0.949); POL3 (0.942); CDC9 (0.911); SMC1 (0.904); MCM4 (0.904); MCM5 (0.899); MCM2 (0.852); PRI1 (0.848); CTF4 (0.84)
Homologues (species, bitscore): RFC1 (Homo sapiens, 427.6); Rfc1 (Mus musculus, 426.4); rfc1 (Danio rerio, 386.3); rfc1 (Xenopus tropicalis, 424.1); Gnf1 (Drosophila melanogaster, 410.2); rfc-1 (Caenorhabditis elegans, 296.6); RFC1 (Arabidopsis thaliana, 339.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:740089-742671:+ | gene-YOR217W_AKU4011 | rna-NM_001183636.1_AKU4011 | cds-NP_014860.1_AKU4011 | 99.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:142118-144703:+ | gene-YOR217W_BG1 | rna-NM_001183636.1_BG1 | cds-NP_014860.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:724920-727446:+ | gene-YOR217W_Bruggeman | rna-NM_001183636.1_Bruggeman | cds-NP_014860.1_Bruggeman | 95.5 | 97.2 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:726195-728780:+ | gene-YOR217W_CAT1 | rna-NM_001183636.1_CAT1 | cds-NP_014860.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:723076-725658:+ | gene-YOR217W_CBS1585 | rna-NM_001183636.1_CBS1585 | cds-NP_014860.1_CBS1585 | 99.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:721760-724345:+ | gene-YOR217W_CBS436 | rna-NM_001183636.1_CBS436 | cds-NP_014860.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:720195-722777:+ | gene-YOR217W_CBS6412 | rna-NM_001183636.1_CBS6412 | cds-NP_014860.1_CBS6412 | 99.3 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:728834-731416:+ | gene-YOR217W_CBS6413 | rna-NM_001183636.1_CBS6413 | cds-NP_014860.1_CBS6413 | 99.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:749067-751652:+ | gene-YOR217W_CENPK1137D | rna-NM_001183636.1_CENPK1137D | cds-NP_014860.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:716227-718809:+ | gene-YOR217W_EthanolRed | rna-NM_001183636.1_EthanolRed | cds-NP_014860.1_EthanolRed | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:721624-724206:+ | gene-YOR217W_FaliES1 | rna-NM_001183636.1_FaliES1 | cds-NP_014860.1_FaliES1 | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:102558-105143:- | gene-YOR217W_JAY291 | rna-NM_001183636.1_JAY291 | cds-NP_014860.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:728883-731468:+ | gene-YOR217W_MUCL30387 | rna-NM_001183636.1_MUCL30387 | cds-NP_014860.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:736300-738885:+ | gene-YOR217W_MUCL30388 | rna-NM_001183636.1_MUCL30388 | cds-NP_014860.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:730405-732987:+ | gene-YOR217W_MUCL39482 | rna-NM_001183636.1_MUCL39482 | cds-NP_014860.1_MUCL39482 | 99.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:739982-742567:+ | gene-YOR217W_MUCL42920 | rna-NM_001183636.1_MUCL42920 | cds-NP_014860.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:749190-751775:+ | gene-YOR217W_NCIM3186 | rna-NM_001183636.1_NCIM3186 | cds-NP_014860.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:730507-733089:+ | gene-YOR217W_NCYC1407 | rna-NM_001183636.1_NCYC1407 | cds-NP_014860.1_NCYC1407 | 99.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:729893-732478:+ | gene-YOR217W_PE2H3 | rna-NM_001183636.1_PE2H3 | cds-NP_014860.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:740270-742855:+ | gene-YOR217W_PE2H4 | rna-NM_001183636.1_PE2H4 | cds-NP_014860.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:749301-751886:+ | gene-YOR217W_S288C | rna-NM_001183636.1_S288C | cds-NP_014860.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:159300-161885:+ | gene-YOR217W_SA1 | rna-NM_001183636.1_SA1 | cds-NP_014860.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:720809-723391:+ | gene-YOR217W_ThermosaccDry | rna-NM_001183636.1_ThermosaccDry | cds-NP_014860.1_ThermosaccDry | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:784334-786919:+ | gene-YOR217W_VR1 | rna-NM_001183636.1_VR1 | cds-NP_014860.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:453711-456293:+ | gene-YOR217W_ZTW1 | rna-NM_001183636.1_ZTW1 | cds-NP_014860.1_ZTW1 | 99.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:726697-729282:+ | gene-YOR217W_Sparadoxus | rna-NM_001183636.1_Sparadoxus | cds-NP_014860.1_Sparadoxus | 90.4 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |