Gene name: RER2
Reference locus (S288C): YBR002C
Gene biotype: protein_coding
Description: Forms the dehydrodolichyl diphosphate syntase (DDS) complex with NUS1; major enzyme of polyprenol synthesis in both the endoplasmic reticulum (ER) and in lipid droplets; participates in ER protein sorting; human ortholog DHDDS functionally complements the heat sensitive growth defect of a ts allele, and is associated with retinitis pigmentosa
Top 10 interactors (score): NUS1 (0.999); ERG20 (0.993); DPM1 (0.979); BTS1 (0.976); RAM2 (0.975); RAM1 (0.962); COQ1 (0.957); SRT1 (0.952); DFG10 (0.947); CAX4 (0.946); SEC59 (0.934); ERG9 (0.928); ALG7 (0.864); LPP1 (0.816); ALG14 (0.733); RIB5 (0.729); CAB5 (0.728); ALG1 (0.721); IDI1 (0.691); MVD1 (0.683)
Homologues (species, bitscore): DHDDS (Homo sapiens, 191.4); Dhdds (Mus musculus, 186.0); dhdds (Danio rerio, 181.4); dhdds (Xenopus tropicalis, 185.7); CG10778 (Drosophila melanogaster, 196.4); T01G1.4 (Caenorhabditis elegans, 172.9); cPT1 (Arabidopsis thaliana, 167.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:230094-230954:- | gene-YBR002C_AKU4011 | rna-NM_001178350.1_AKU4011 | cds-NP_009556.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:220203-221063:- | gene-YBR002C_BG1 | rna-NM_001178350.1_BG1 | cds-NP_009556.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:230794-231654:- | gene-YBR002C_Bruggeman | rna-NM_001178350.1_Bruggeman | cds-NP_009556.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:233085-233945:- | gene-YBR002C_CAT1 | rna-NM_001178350.1_CAT1 | cds-NP_009556.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:222132-222992:- | gene-YBR002C_CBS1585 | rna-NM_001178350.1_CBS1585 | cds-NP_009556.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:230375-231235:- | gene-YBR002C_CBS436 | rna-NM_001178350.1_CBS436 | cds-NP_009556.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:320634-321494:- | gene-YBR002C_CBS6412 | rna-NM_001178350.1_CBS6412 | cds-NP_009556.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:227497-228357:- | gene-YBR002C_CBS6413 | rna-NM_001178350.1_CBS6413 | cds-NP_009556.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:241394-242254:- | gene-YBR002C_CENPK1137D | rna-NM_001178350.1_CENPK1137D | cds-NP_009556.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:357092-357952:- | gene-YBR002C_EthanolRed | rna-NM_001178350.1_EthanolRed | cds-NP_009556.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:245188-246048:- | gene-YBR002C_FaliES1 | rna-NM_001178350.1_FaliES1 | cds-NP_009556.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000048.1:51549-52409:+ | gene-YBR002C_JAY291 | rna-NM_001178350.1_JAY291 | cds-NP_009556.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:231151-232011:- | gene-YBR002C_MUCL30387 | rna-NM_001178350.1_MUCL30387 | cds-NP_009556.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:231091-231951:- | gene-YBR002C_MUCL30388 | rna-NM_001178350.1_MUCL30388 | cds-NP_009556.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:222113-222973:- | gene-YBR002C_MUCL39482 | rna-NM_001178350.1_MUCL39482 | cds-NP_009556.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:229554-230414:- | gene-YBR002C_MUCL42920 | rna-NM_001178350.1_MUCL42920 | cds-NP_009556.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:241505-242365:- | gene-YBR002C_NCIM3186 | rna-NM_001178350.1_NCIM3186 | cds-NP_009556.1_NCIM3186 | 98.0 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:223288-224148:- | gene-YBR002C_NCYC1407 | rna-NM_001178350.1_NCYC1407 | cds-NP_009556.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:235450-236310:- | gene-YBR002C_PE2H3 | rna-NM_001178350.1_PE2H3 | cds-NP_009556.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:233115-233975:- | gene-YBR002C_PE2H4 | rna-NM_001178350.1_PE2H4 | cds-NP_009556.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:241708-242568:- | gene-YBR002C_S288C | rna-NM_001178350.1_S288C | cds-NP_009556.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000037.1:60205-61065:+ | gene-YBR002C_SA1 | rna-NM_001178350.1_SA1 | cds-NP_009556.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:244897-245757:- | gene-YBR002C_ThermosaccDry | rna-NM_001178350.1_ThermosaccDry | cds-NP_009556.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:226791-227651:- | gene-YBR002C_VR1 | rna-NM_001178350.1_VR1 | cds-NP_009556.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:220880-221740:- | gene-YBR002C_ZTW1 | rna-NM_001178350.1_ZTW1 | cds-NP_009556.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:256583-257443:- | gene-YBR002C_Sparadoxus | rna-NM_001178350.1_Sparadoxus | cds-NP_009556.1_Sparadoxus | 93.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |