Gene name: REF2
Reference locus (S288C): YDR195W
Gene biotype: protein_coding
Description: RNA end formation protein 2; RNA-binding protein; involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation, and in snoRNA maturation; part of holo-CPF subcomplex APT, which associates with 3'-ends of snoRNA- and mRNA-encoding genes; putative regulatory subunit of type 1 protein phosphatase Glc7p, required for actomyosin ring formation, and for timely dephosphorylation and release of Bnr1p from the division site; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): MPE1 (0.999); YSH1 (0.999); SYC1 (0.999); YTH1 (0.999); PFS2 (0.999); SSU72 (0.999); RNA14 (0.999); SWD2 (0.999); GLC7 (0.999); CFT2 (0.999); PAP1 (0.999); PTA1 (0.999); CFT1 (0.999); PTI1 (0.999); FIP1 (0.999); RNA15 (0.935); PCF11 (0.925); CLP1 (0.91); HRP1 (0.851); PPQ1 (0.81)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:817131-818735:+ | gene-YDR195W_AKU4011 | rna-NM_001180503.3_AKU4011 | cds-NP_010481.3_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:307085-308686:- | gene-YDR195W_BG1 | rna-NM_001180503.3_BG1 | cds-NP_010481.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:849543-851147:+ | gene-YDR195W_Bruggeman | rna-NM_001180503.3_Bruggeman | cds-NP_010481.3_Bruggeman | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:836813-838414:+ | gene-YDR195W_CAT1 | rna-NM_001180503.3_CAT1 | cds-NP_010481.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:807491-809095:+ | gene-YDR195W_CBS1585 | rna-NM_001180503.3_CBS1585 | cds-NP_010481.3_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:836497-838098:+ | gene-YDR195W_CBS436 | rna-NM_001180503.3_CBS436 | cds-NP_010481.3_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:804298-805902:+ | gene-YDR195W_CBS6412 | rna-NM_001180503.3_CBS6412 | cds-NP_010481.3_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:834842-836446:+ | gene-YDR195W_CBS6413 | rna-NM_001180503.3_CBS6413 | cds-NP_010481.3_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:847431-849032:+ | gene-YDR195W_CENPK1137D | rna-NM_001180503.3_CENPK1137D | cds-NP_010481.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:817883-819487:+ | gene-YDR195W_EthanolRed | rna-NM_001180503.3_EthanolRed | cds-NP_010481.3_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:826095-827699:+ | gene-YDR195W_FaliES1 | rna-NM_001180503.3_FaliES1 | cds-NP_010481.3_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000068.1:21655-23256:- | gene-YDR195W_JAY291 | rna-NM_001180503.3_JAY291 | cds-NP_010481.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:835196-836800:+ | gene-YDR195W_MUCL30387 | rna-NM_001180503.3_MUCL30387 | cds-NP_010481.3_MUCL30387 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:823445-825049:+ | gene-YDR195W_MUCL30388 | rna-NM_001180503.3_MUCL30388 | cds-NP_010481.3_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:808938-810542:+ | gene-YDR195W_MUCL39482 | rna-NM_001180503.3_MUCL39482 | cds-NP_010481.3_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:747638-749239:+ | gene-YDR195W_MUCL42920 | rna-NM_001180503.3_MUCL42920 | cds-NP_010481.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:848522-850123:+ | gene-YDR195W_NCIM3186 | rna-NM_001180503.3_NCIM3186 | cds-NP_010481.3_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:812072-813676:+ | gene-YDR195W_NCYC1407 | rna-NM_001180503.3_NCYC1407 | cds-NP_010481.3_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:828824-830428:+ | gene-YDR195W_PE2H3 | rna-NM_001180503.3_PE2H3 | cds-NP_010481.3_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:828129-829733:+ | gene-YDR195W_PE2H4 | rna-NM_001180503.3_PE2H4 | cds-NP_010481.3_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:848599-850200:+ | gene-YDR195W_S288C | rna-NM_001180503.3_S288C | cds-NP_010481.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:194308-195912:+ | gene-YDR195W_SA1 | rna-NM_001180503.3_SA1 | cds-NP_010481.3_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:824250-825854:+ | gene-YDR195W_ThermosaccDry | rna-NM_001180503.3_ThermosaccDry | cds-NP_010481.3_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:839477-841081:+ | gene-YDR195W_VR1 | rna-NM_001180503.3_VR1 | cds-NP_010481.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:86968-88572:+ | gene-YDR195W_ZTW1 | rna-NM_001180503.3_ZTW1 | cds-NP_010481.3_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:829117-830715:+ | gene-YDR195W_Sparadoxus | rna-NM_001180503.3_Sparadoxus | cds-NP_010481.3_Sparadoxus | 90.6 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |