Gene name: RDH54
Reference locus (S288C): YBR073W
Gene biotype: protein_coding
Description: DNA-dependent ATPase; DNA recombination/repair translocase, supercoils DNA and promotes DNA strand opening; stimulates strand exchange by modifying dsDNA topology; involved in recombinational repair of DNA double-strand breaks (DSBs) during mitosis and meiosis; phosphorylated in Mec1p-, Rad53p-dependent way in response to one DSB; contributes to remodelling of nucleosomes; proposed to be involved in crossover interference; interacts with Dmc1p; stimulates Dmc1p and Rad51p
Top 10 interactors (score): RAD51 (0.999); DMC1 (0.984); RAD52 (0.979); SGS1 (0.979); RAD57 (0.972); RAD54 (0.968); SRS2 (0.964); RAD59 (0.962); MEC1 (0.959); SPO11 (0.938); RAD1 (0.931); DNL4 (0.907); RAD53 (0.906); RFA1 (0.903); EXO1 (0.902); RAD55 (0.899); TOP3 (0.89); MUS81 (0.889); YKU70 (0.888); MND1 (0.88)
Homologues (species, bitscore): RAD54B (Homo sapiens, 461.1); Rad54b (Mus musculus, 440.3); rad54b (Danio rerio, 441.8); rad54l (Xenopus tropicalis, 345.1); okr (Drosophila melanogaster, 395.2); rad-54 (Caenorhabditis elegans, 408.7); RAD54 (Arabidopsis thaliana, 379.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:365496-368373:+ | gene-YBR073W_AKU4011 | rna-NM_001178421.4_AKU4011 | cds-NP_009629.6_AKU4011 | 99.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:356474-359351:+ | gene-YBR073W_BG1 | rna-NM_001178421.4_BG1 | cds-NP_009629.6_BG1 | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:366732-369609:+ | gene-YBR073W_Bruggeman | rna-NM_001178421.4_Bruggeman | cds-NP_009629.6_Bruggeman | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:370019-372896:+ | gene-YBR073W_CAT1 | rna-NM_001178421.4_CAT1 | cds-NP_009629.6_CAT1 | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:357778-360655:+ | gene-YBR073W_CBS1585 | rna-NM_001178421.4_CBS1585 | cds-NP_009629.6_CBS1585 | 99.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:365854-368731:+ | gene-YBR073W_CBS436 | rna-NM_001178421.4_CBS436 | cds-NP_009629.6_CBS436 | 99.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:456009-458886:+ | gene-YBR073W_CBS6412 | rna-NM_001178421.4_CBS6412 | cds-NP_009629.6_CBS6412 | 99.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:362920-365797:+ | gene-YBR073W_CBS6413 | rna-NM_001178421.4_CBS6413 | cds-NP_009629.6_CBS6413 | 99.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:376872-379749:+ | gene-YBR073W_CENPK1137D | rna-NM_001178421.4_CENPK1137D | cds-NP_009629.6_CENPK1137D | 99.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:492282-495159:+ | gene-YBR073W_EthanolRed | rna-NM_001178421.4_EthanolRed | cds-NP_009629.6_EthanolRed | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:381560-384437:+ | gene-YBR073W_FaliES1 | rna-NM_001178421.4_FaliES1 | cds-NP_009629.6_FaliES1 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000124.1:29498-32375:+ | gene-YBR073W_JAY291 | rna-NM_001178421.4_JAY291 | cds-NP_009629.6_JAY291 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:367882-370759:+ | gene-YBR073W_MUCL30387 | rna-NM_001178421.4_MUCL30387 | cds-NP_009629.6_MUCL30387 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:367921-370798:+ | gene-YBR073W_MUCL30388 | rna-NM_001178421.4_MUCL30388 | cds-NP_009629.6_MUCL30388 | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:357766-360643:+ | gene-YBR073W_MUCL39482 | rna-NM_001178421.4_MUCL39482 | cds-NP_009629.6_MUCL39482 | 99.7 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:364984-367861:+ | gene-YBR073W_MUCL42920 | rna-NM_001178421.4_MUCL42920 | cds-NP_009629.6_MUCL42920 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:382909-385785:+ | gene-YBR073W_NCIM3186 | rna-NM_001178421.4_NCIM3186 | cds-NP_009629.6_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:358702-361579:+ | gene-YBR073W_NCYC1407 | rna-NM_001178421.4_NCYC1407 | cds-NP_009629.6_NCYC1407 | 99.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:370947-373824:+ | gene-YBR073W_PE2H3 | rna-NM_001178421.4_PE2H3 | cds-NP_009629.6_PE2H3 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:368623-371500:+ | gene-YBR073W_PE2H4 | rna-NM_001178421.4_PE2H4 | cds-NP_009629.6_PE2H4 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:383112-385988:+ | gene-YBR073W_S288C | rna-NM_001178421.4_S288C | cds-NP_009629.6_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000017.1:91524-94401:- | gene-YBR073W_SA1 | rna-NM_001178421.4_SA1 | cds-NP_009629.6_SA1 | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:380571-383448:+ | gene-YBR073W_ThermosaccDry | rna-NM_001178421.4_ThermosaccDry | cds-NP_009629.6_ThermosaccDry | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:362565-365442:+ | gene-YBR073W_VR1 | rna-NM_001178421.4_VR1 | cds-NP_009629.6_VR1 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:356246-359123:+ | gene-YBR073W_ZTW1 | rna-NM_001178421.4_ZTW1 | cds-NP_009629.6_ZTW1 | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:393270-396148:+ | gene-YBR073W_Sparadoxus | rna-NM_001178421.4_Sparadoxus | cds-NP_009629.6_Sparadoxus | 87.8 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |