Gene name: RCM1
Reference locus (S288C): YNL022C
Gene biotype: protein_coding
Description: rRNA m5C methyltransferase; methylates cytosine at position 2278 of 25S rRNA while Nop2p methylates cytosine at position 2870; contains seven beta-strand methyltransferase motif; localized to the nucleolus; interacts with Trm112p; homolog of NSUN5A, a human gene which is deleted in Williams-Beuren Syndrome
Top 10 interactors (score): YGR283C (0.962); EFM2 (0.942); YMR310C (0.937); NOP14 (0.867); BMT5 (0.864); YCR087C-A (0.85); NOP13 (0.839); RPF2 (0.837); DIM1 (0.836); PUF6 (0.836); KRE33 (0.817); BCP1 (0.809); TRM112 (0.796); DIP2 (0.795); NOP7 (0.791); RRP8 (0.784); SFM1 (0.781); YCR016W (0.78); ERB1 (0.768); TRM11 (0.764)
Homologues (species, bitscore): NSUN5 (Homo sapiens, 179.9); Nsun5 (Mus musculus, 184.5); nsun5 (Danio rerio, 170.6); nsun5 (Xenopus tropicalis, 181.4); CG42358 (Drosophila melanogaster, 112.1); nsun-5 (Caenorhabditis elegans, 162.9); AT5G26180 (Arabidopsis thaliana, 170.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:573886-575358:- | gene-YNL022C_AKU4011 | rna-NM_001182861.3_AKU4011 | cds-NP_014376.3_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:464786-466258:+ | gene-YNL022C_BG1 | rna-NM_001182861.3_BG1 | cds-NP_014376.3_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:591306-592778:- | gene-YNL022C_Bruggeman | rna-NM_001182861.3_Bruggeman | cds-NP_014376.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:626755-628227:- | gene-YNL022C_CAT1 | rna-NM_001182861.3_CAT1 | cds-NP_014376.3_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:579570-581042:- | gene-YNL022C_CBS1585 | rna-NM_001182861.3_CBS1585 | cds-NP_014376.3_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:641980-643452:- | gene-YNL022C_CBS436 | rna-NM_001182861.3_CBS436 | cds-NP_014376.3_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:569403-570875:- | gene-YNL022C_CBS6412 | rna-NM_001182861.3_CBS6412 | cds-NP_014376.3_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:570744-572216:- | gene-YNL022C_CBS6413 | rna-NM_001182861.3_CBS6413 | cds-NP_014376.3_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:585034-586506:- | gene-YNL022C_CENPK1137D | rna-NM_001182861.3_CENPK1137D | cds-NP_014376.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:575972-577444:- | gene-YNL022C_EthanolRed | rna-NM_001182861.3_EthanolRed | cds-NP_014376.3_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:566996-568468:- | gene-YNL022C_FaliES1 | rna-NM_001182861.3_FaliES1 | cds-NP_014376.3_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000387.1:5367-6839:+ | gene-YNL022C_JAY291 | rna-NM_001182861.3_JAY291 | cds-NP_014376.3_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:587188-588660:- | gene-YNL022C_MUCL30387 | rna-NM_001182861.3_MUCL30387 | cds-NP_014376.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:629982-631454:- | gene-YNL022C_MUCL30388 | rna-NM_001182861.3_MUCL30388 | cds-NP_014376.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:571165-572637:- | gene-YNL022C_MUCL39482 | rna-NM_001182861.3_MUCL39482 | cds-NP_014376.3_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:574723-576195:- | gene-YNL022C_MUCL42920 | rna-NM_001182861.3_MUCL42920 | cds-NP_014376.3_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:591396-592868:- | gene-YNL022C_NCIM3186 | rna-NM_001182861.3_NCIM3186 | cds-NP_014376.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:573370-574842:- | gene-YNL022C_NCYC1407 | rna-NM_001182861.3_NCYC1407 | cds-NP_014376.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:575893-577365:- | gene-YNL022C_PE2H3 | rna-NM_001182861.3_PE2H3 | cds-NP_014376.3_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:577211-578683:- | gene-YNL022C_PE2H4 | rna-NM_001182861.3_PE2H4 | cds-NP_014376.3_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:591427-592899:- | gene-YNL022C_S288C | rna-NM_001182861.3_S288C | cds-NP_014376.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000109.1:17452-18924:- | gene-YNL022C_SA1 | rna-NM_001182861.3_SA1 | cds-NP_014376.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:567583-569055:- | gene-YNL022C_ThermosaccDry | rna-NM_001182861.3_ThermosaccDry | cds-NP_014376.3_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:573696-575168:+ | gene-YNL022C_VR1 | rna-NM_001182861.3_VR1 | cds-NP_014376.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:464385-465857:+ | gene-YNL022C_ZTW1 | rna-NM_001182861.3_ZTW1 | cds-NP_014376.3_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:582683-584155:- | gene-YNL022C_Sparadoxus | rna-NM_001182861.3_Sparadoxus | cds-NP_014376.3_Sparadoxus | 91.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |