RCF1 (YML030W)


Gene profile

Gene name: RCF1
Reference locus (S288C): YML030W
Gene biotype: protein_coding

Description: Respiratory supercomplex factor 1, mitochondrial; Cytochrome c oxidase subunit; required for assembly of the Complex III-Complex IV supercomplex, and for assembly of Cox13p and Rcf2p into cytochrome c oxidase; similar to Rcf2p, and either Rcf1p or Rcf2p is required for late-stage assembly of the Cox12p and Cox13p subunits and for cytochrome c oxidase activity; required for growth under hypoxic conditions; member of the hypoxia induced gene family; C. elegans and human orthologs are functional in yeast

Top 10 interactors (score): COX12 (0.999); COX13 (0.978); RCF2 (0.967); COR1 (0.946); COX3 (0.942); COX4 (0.931); COX2 (0.93); CYT1 (0.873); RCF3 (0.864); QCR2 (0.849); COX1 (0.84); DBP10 (0.821); COX26 (0.797); AIM36 (0.779); PUF3 (0.763); ADE1 (0.761); PET9 (0.756); COX6 (0.745); MRH4 (0.732); NUF2 (0.716)

Homologues (species, bitscore): CG9921 (Drosophila melanogaster, 54.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:266029-266508:+ gene-YML030W_AKU4011 rna-NM_001182388.1_AKU4011 cds-NP_013682.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:276363-276842:- gene-YML030W_BG1 rna-NM_001182388.1_BG1 cds-NP_013682.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:205983-206462:+ gene-YML030W_Bruggeman rna-NM_001182388.1_Bruggeman cds-NP_013682.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:208496-208975:+ gene-YML030W_CAT1 rna-NM_001182388.1_CAT1 cds-NP_013682.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:198978-199457:+ gene-YML030W_CBS1585 rna-NM_001182388.1_CBS1585 cds-NP_013682.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:204516-204995:+ gene-YML030W_CBS436 rna-NM_001182388.1_CBS436 cds-NP_013682.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:312717-313196:+ gene-YML030W_CBS6412 rna-NM_001182388.1_CBS6412 cds-NP_013682.1_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:198236-198715:+ gene-YML030W_CBS6413 rna-NM_001182388.1_CBS6413 cds-NP_013682.1_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:210958-211437:+ gene-YML030W_CENPK1137D rna-NM_001182388.1_CENPK1137D cds-NP_013682.1_CENPK1137D 99.7 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:199005-199484:+ gene-YML030W_EthanolRed rna-NM_001182388.1_EthanolRed cds-NP_013682.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:201969-202448:+ gene-YML030W_FaliES1 rna-NM_001182388.1_FaliES1 cds-NP_013682.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000237.1:9690-10169:- gene-YML030W_JAY291 rna-NM_001182388.1_JAY291 cds-NP_013682.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:203715-204194:+ gene-YML030W_MUCL30387 rna-NM_001182388.1_MUCL30387 cds-NP_013682.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:207692-208171:+ gene-YML030W_MUCL30388 rna-NM_001182388.1_MUCL30388 cds-NP_013682.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:199264-199743:+ gene-YML030W_MUCL39482 rna-NM_001182388.1_MUCL39482 cds-NP_013682.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:204821-205300:+ gene-YML030W_MUCL42920 rna-NM_001182388.1_MUCL42920 cds-NP_013682.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:216389-216868:+ gene-YML030W_NCIM3186 rna-NM_001182388.1_NCIM3186 cds-NP_013682.1_NCIM3186 100.0 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:199207-199686:+ gene-YML030W_NCYC1407 rna-NM_001182388.1_NCYC1407 cds-NP_013682.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:205107-205586:+ gene-YML030W_PE2H3 rna-NM_001182388.1_PE2H3 cds-NP_013682.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:211202-211681:+ gene-YML030W_PE2H4 rna-NM_001182388.1_PE2H4 cds-NP_013682.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:216435-216914:+ gene-YML030W_S288C rna-NM_001182388.1_S288C cds-NP_013682.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000088.1:21935-22414:- gene-YML030W_SA1 rna-NM_001182388.1_SA1 cds-NP_013682.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:199042-199521:+ gene-YML030W_ThermosaccDry rna-NM_001182388.1_ThermosaccDry cds-NP_013682.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:203048-203527:+ gene-YML030W_VR1 rna-NM_001182388.1_VR1 cds-NP_013682.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:178095-178574:+ gene-YML030W_ZTW1 rna-NM_001182388.1_ZTW1 cds-NP_013682.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:209843-210322:+ gene-YML030W_Sparadoxus rna-NM_001182388.1_Sparadoxus cds-NP_013682.1_Sparadoxus 91.4 100.0 Verified 1 1 1 False True False False False

Additional files