RAS2 (YNL098C)


Gene profile

Gene name: RAS2
Reference locus (S288C): YNL098C
Gene biotype: protein_coding

Description: Ras-like protein 2; GTP-binding protein; regulates nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes; RAS2 has a paralog, RAS1, that arose from the whole genome duplication; Belongs to the small GTPase superfamily. Ras family

Top 10 interactors (score): CDC25 (0.999); CYR1 (0.999); STE11 (0.998); TPK1 (0.998); TPK2 (0.997); TPK3 (0.996); IRA2 (0.996); STE7 (0.996); GPA2 (0.994); IRA1 (0.994); BCY1 (0.992); GPR1 (0.986); SCH9 (0.984); RAS1 (0.983); LTE1 (0.976); PDE2 (0.975); TOR1 (0.964); CDC24 (0.954); RIM15 (0.942); STE20 (0.94)

Homologues (species, bitscore): RRAS2 (Homo sapiens, 221.5); Rras2 (Mus musculus, 221.5); zgc:55558 (Danio rerio, 223.4); kras (Xenopus tropicalis, 217.6); Ras85D (Drosophila melanogaster, 221.1); rap-1 (Caenorhabditis elegans, 214.2); RA-5 (Arabidopsis thaliana, 107.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:433272-434240:- gene-YNL098C_AKU4011 rna-NM_001182936.1_AKU4011 cds-NP_014301.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:337267-338235:- gene-YNL098C_BG1 rna-NM_001182936.1_BG1 cds-NP_014301.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:443988-444956:- gene-YNL098C_Bruggeman rna-NM_001182936.1_Bruggeman cds-NP_014301.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:487021-487989:- gene-YNL098C_CAT1 rna-NM_001182936.1_CAT1 cds-NP_014301.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:433875-434843:- gene-YNL098C_CBS1585 rna-NM_001182936.1_CBS1585 cds-NP_014301.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:502286-503254:- gene-YNL098C_CBS436 rna-NM_001182936.1_CBS436 cds-NP_014301.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:429038-430006:- gene-YNL098C_CBS6412 rna-NM_001182936.1_CBS6412 cds-NP_014301.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:430356-431324:- gene-YNL098C_CBS6413 rna-NM_001182936.1_CBS6413 cds-NP_014301.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:433454-434422:- gene-YNL098C_CENPK1137D rna-NM_001182936.1_CENPK1137D cds-NP_014301.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:430280-431248:- gene-YNL098C_EthanolRed rna-NM_001182936.1_EthanolRed cds-NP_014301.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:426178-427146:- gene-YNL098C_FaliES1 rna-NM_001182936.1_FaliES1 cds-NP_014301.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000140.1:13788-14756:- gene-YNL098C_JAY291 rna-NM_001182936.1_JAY291 cds-NP_014301.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:440162-441130:- gene-YNL098C_MUCL30387 rna-NM_001182936.1_MUCL30387 cds-NP_014301.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:475539-476507:- gene-YNL098C_MUCL30388 rna-NM_001182936.1_MUCL30388 cds-NP_014301.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:431279-432247:- gene-YNL098C_MUCL39482 rna-NM_001182936.1_MUCL39482 cds-NP_014301.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:435286-436254:- gene-YNL098C_MUCL42920 rna-NM_001182936.1_MUCL42920 cds-NP_014301.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:439571-440539:- gene-YNL098C_NCIM3186 rna-NM_001182936.1_NCIM3186 cds-NP_014301.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:433394-434362:- gene-YNL098C_NCYC1407 rna-NM_001182936.1_NCYC1407 cds-NP_014301.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:432299-433267:- gene-YNL098C_PE2H3 rna-NM_001182936.1_PE2H3 cds-NP_014301.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:431705-432673:- gene-YNL098C_PE2H4 rna-NM_001182936.1_PE2H4 cds-NP_014301.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:439602-440570:- gene-YNL098C_S288C rna-NM_001182936.1_S288C cds-NP_014301.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000024.1:24566-25534:- gene-YNL098C_SA1 rna-NM_001182936.1_SA1 cds-NP_014301.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:427053-428021:- gene-YNL098C_ThermosaccDry rna-NM_001182936.1_ThermosaccDry cds-NP_014301.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:445746-446714:- gene-YNL098C_VR1 rna-NM_001182936.1_VR1 cds-NP_014301.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:336851-337819:- gene-YNL098C_ZTW1 rna-NM_001182936.1_ZTW1 cds-NP_014301.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:437915-438883:- gene-YNL098C_Sparadoxus rna-NM_001182936.1_Sparadoxus cds-NP_014301.1_Sparadoxus 91.8 100.0 Verified 1 1 1 False True False False False

Additional files