RAS1 (YOR101W)


Gene profile

Gene name: RAS1
Reference locus (S288C): YOR101W
Gene biotype: protein_coding

Description: Ras-like protein 1; GTPase involved in G-protein signaling in adenylate cyclase activation; plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes; relative distribution to the nucleus increases upon DNA replication stress; RAS1 has a paralog, RAS2, that arose from the whole genome duplication

Top 10 interactors (score): CYR1 (0.999); CDC25 (0.999); STE11 (0.997); TPK1 (0.997); TPK2 (0.994); IRA2 (0.991); STE7 (0.99); IRA1 (0.989); TPK3 (0.987); BCY1 (0.987); RAS2 (0.983); GPA2 (0.974); GPR1 (0.961); CDC24 (0.927); GPA1 (0.92); HOG1 (0.904); PDE2 (0.898); HSP82 (0.896); TOR1 (0.896); HSC82 (0.883)

Homologues (species, bitscore): RRAS2 (Homo sapiens, 236.1); Rras2 (Mus musculus, 236.1); rras2 (Danio rerio, 235.3); rras (Xenopus tropicalis, 222.2); Ras85D (Drosophila melanogaster, 225.7); ras-1 (Caenorhabditis elegans, 221.1); RABC2A (Arabidopsis thaliana, 114.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:499320-500249:+ gene-YOR101W_AKU4011 rna-NM_001183520.1_AKU4011 cds-NP_014744.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000171.1:78805-79734:- gene-YOR101W_BG1 rna-NM_001183520.1_BG1 cds-NP_014744.1_BG1 96.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:502906-503835:+ gene-YOR101W_Bruggeman rna-NM_001183520.1_Bruggeman cds-NP_014744.1_Bruggeman 96.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:502880-503809:+ gene-YOR101W_CAT1 rna-NM_001183520.1_CAT1 cds-NP_014744.1_CAT1 96.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:494612-495541:+ gene-YOR101W_CBS1585 rna-NM_001183520.1_CBS1585 cds-NP_014744.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:499641-500570:+ gene-YOR101W_CBS436 rna-NM_001183520.1_CBS436 cds-NP_014744.1_CBS436 96.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:493353-494282:+ gene-YOR101W_CBS6412 rna-NM_001183520.1_CBS6412 cds-NP_014744.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:500648-501577:+ gene-YOR101W_CBS6413 rna-NM_001183520.1_CBS6413 cds-NP_014744.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:515306-516235:+ gene-YOR101W_CENPK1137D rna-NM_001183520.1_CENPK1137D cds-NP_014744.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:495852-496781:+ gene-YOR101W_EthanolRed rna-NM_001183520.1_EthanolRed cds-NP_014744.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:499361-500290:+ gene-YOR101W_FaliES1 rna-NM_001183520.1_FaliES1 cds-NP_014744.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000063.1:58951-59880:- gene-YOR101W_JAY291 rna-NM_001183520.1_JAY291 cds-NP_014744.1_JAY291 96.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:507442-508371:+ gene-YOR101W_MUCL30387 rna-NM_001183520.1_MUCL30387 cds-NP_014744.1_MUCL30387 96.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:512630-513559:+ gene-YOR101W_MUCL30388 rna-NM_001183520.1_MUCL30388 cds-NP_014744.1_MUCL30388 96.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:502257-503186:+ gene-YOR101W_MUCL39482 rna-NM_001183520.1_MUCL39482 cds-NP_014744.1_MUCL39482 99.6 100.0 Verified 1 1 0 False False True False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:518350-519279:+ gene-YOR101W_MUCL42920 rna-NM_001183520.1_MUCL42920 cds-NP_014744.1_MUCL42920 97.0 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:515133-516062:+ gene-YOR101W_NCIM3186 rna-NM_001183520.1_NCIM3186 cds-NP_014744.1_NCIM3186 96.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:508709-509638:+ gene-YOR101W_NCYC1407 rna-NM_001183520.1_NCYC1407 cds-NP_014744.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:507713-508642:+ gene-YOR101W_PE2H3 rna-NM_001183520.1_PE2H3 cds-NP_014744.1_PE2H3 96.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:518089-519018:+ gene-YOR101W_PE2H4 rna-NM_001183520.1_PE2H4 cds-NP_014744.1_PE2H4 96.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:515244-516173:+ gene-YOR101W_S288C rna-NM_001183520.1_S288C cds-NP_014744.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000098.1:6636-7565:- gene-YOR101W_SA1 rna-NM_001183520.1_SA1 cds-NP_014744.1_SA1 96.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:498515-499444:+ gene-YOR101W_ThermosaccDry rna-NM_001183520.1_ThermosaccDry cds-NP_014744.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:500640-501569:+ gene-YOR101W_VR1 rna-NM_001183520.1_VR1 cds-NP_014744.1_VR1 96.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:232503-233431:+ gene-YOR101W_ZTW1 rna-NM_001183520.1_ZTW1 cds-NP_014744.1_ZTW1 99.1 99.8 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:504459-505400:+ gene-YOR101W_Sparadoxus rna-NM_001183520.1_Sparadoxus cds-NP_014744.1_Sparadoxus 87.0 100.0 Verified 1 1 1 False True False False False

Additional files