RAP1 (YNL216W)


Gene profile

Gene name: RAP1
Reference locus (S288C): YNL216W
Gene biotype: protein_coding

Description: DNA-binding protein RAP1; Essential DNA-binding transcription regulator that binds many loci; involved in transcription activation, repression, chromatin silencing, telomere length maintenance; relocalizes to cytosol under hypoxia; conserved protein with N-terminal BRCT domain, central region with homology to Myb DNA binding domain, and C-terminal Rap1-specific protein-interaction domain (RCT domain); recruits Sir complex to telomeric DNA; present in quiescent cell telomere hyperclusters

Top 10 interactors (score): RIF2 (0.999); SIR3 (0.999); RIF1 (0.999); SIR4 (0.998); GCR1 (0.991); FHL1 (0.979); IFH1 (0.971); ABF1 (0.968); CDC13 (0.959); TBF1 (0.928); TEN1 (0.926); STN1 (0.916); GCN4 (0.907); REB1 (0.902); GCR2 (0.894); SIR2 (0.875); SIR1 (0.874); SFP1 (0.868); ESA1 (0.861); YKU70 (0.832)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:235471-237954:+ gene-YNL216W_AKU4011 rna-NM_001183054.1_AKU4011 cds-NP_014183.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:139414-141897:+ gene-YNL216W_BG1 rna-NM_001183054.1_BG1 cds-NP_014183.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:245514-247997:+ gene-YNL216W_Bruggeman rna-NM_001183054.1_Bruggeman cds-NP_014183.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:252668-255151:+ gene-YNL216W_CAT1 rna-NM_001183054.1_CAT1 cds-NP_014183.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:235866-238349:+ gene-YNL216W_CBS1585 rna-NM_001183054.1_CBS1585 cds-NP_014183.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:230945-233428:+ gene-YNL216W_CBS436 rna-NM_001183054.1_CBS436 cds-NP_014183.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:231904-234387:+ gene-YNL216W_CBS6412 rna-NM_001183054.1_CBS6412 cds-NP_014183.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:232550-235033:+ gene-YNL216W_CBS6413 rna-NM_001183054.1_CBS6413 cds-NP_014183.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:235490-237973:+ gene-YNL216W_CENPK1137D rna-NM_001183054.1_CENPK1137D cds-NP_014183.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:233108-235591:+ gene-YNL216W_EthanolRed rna-NM_001183054.1_EthanolRed cds-NP_014183.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:227850-230333:+ gene-YNL216W_FaliES1 rna-NM_001183054.1_FaliES1 cds-NP_014183.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000082.1:139007-141490:+ gene-YNL216W_JAY291 rna-NM_001183054.1_JAY291 cds-NP_014183.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:241050-243533:+ gene-YNL216W_MUCL30387 rna-NM_001183054.1_MUCL30387 cds-NP_014183.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:239631-242114:+ gene-YNL216W_MUCL30388 rna-NM_001183054.1_MUCL30388 cds-NP_014183.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:233356-235839:+ gene-YNL216W_MUCL39482 rna-NM_001183054.1_MUCL39482 cds-NP_014183.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:235612-238095:+ gene-YNL216W_MUCL42920 rna-NM_001183054.1_MUCL42920 cds-NP_014183.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:241658-244141:+ gene-YNL216W_NCIM3186 rna-NM_001183054.1_NCIM3186 cds-NP_014183.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:235446-237929:+ gene-YNL216W_NCYC1407 rna-NM_001183054.1_NCYC1407 cds-NP_014183.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:232352-234835:+ gene-YNL216W_PE2H3 rna-NM_001183054.1_PE2H3 cds-NP_014183.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:231740-234223:+ gene-YNL216W_PE2H4 rna-NM_001183054.1_PE2H4 cds-NP_014183.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:241689-244172:+ gene-YNL216W_S288C rna-NM_001183054.1_S288C cds-NP_014183.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000040.1:8137-10620:- gene-YNL216W_SA1 rna-NM_001183054.1_SA1 cds-NP_014183.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:228706-231189:+ gene-YNL216W_ThermosaccDry rna-NM_001183054.1_ThermosaccDry cds-NP_014183.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:247708-250191:+ gene-YNL216W_VR1 rna-NM_001183054.1_VR1 cds-NP_014183.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:139035-141518:+ gene-YNL216W_ZTW1 rna-NM_001183054.1_ZTW1 cds-NP_014183.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:239117-241615:+ gene-YNL216W_Sparadoxus rna-NM_001183054.1_Sparadoxus cds-NP_014183.1_Sparadoxus 89.3 99.5 Verified 1 1 1 False True False False False

Additional files