Gene name: RAM2
Reference locus (S288C): YKL019W
Gene biotype: protein_coding
Description: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I; farnesyltransferase (Ram2p-Ram1p heterodimer) catalyzes the addition of 15-carbon isoprenoid farnesyl to substrate proteins containing a CAAX consensus motif; type I geranylgeranyltransferase (Ram2p-Cdc43p heterodimer) catalyzes the addition of the 20-carbon isoprenoid geranylgeranyl to substrate proteins containing a CaaL consensus motif; required for membrane localization of Ras proteins and a-factor
Top 10 interactors (score): CDC43 (0.999); RAM1 (0.999); STE24 (0.998); RCE1 (0.997); STE14 (0.99); RER2 (0.975); BET2 (0.974); SRT1 (0.962); BTS1 (0.929); AXL1 (0.919); ERG20 (0.917); NUS1 (0.914); STE6 (0.913); COQ1 (0.908); ERG9 (0.839); MF(ALPHA)1 (0.782); MCM4 (0.773); STE23 (0.761); STE2 (0.723); MFA1 (0.699)
Homologues (species, bitscore): FNTA (Homo sapiens, 136.3); Fnta (Mus musculus, 138.7); fnta (Danio rerio, 133.7); fnta (Xenopus tropicalis, 135.6); Fnta (Drosophila melanogaster, 145.6); fnta-1 (Caenorhabditis elegans, 109.4); FTA (Arabidopsis thaliana, 119.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:388585-389535:+ | gene-YKL019W_AKU4011 | rna-NM_001179585.3_AKU4011 | cds-NP_012906.3_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:254369-255319:- | gene-YKL019W_BG1 | rna-NM_001179585.3_BG1 | cds-NP_012906.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:410288-411238:+ | gene-YKL019W_Bruggeman | rna-NM_001179585.3_Bruggeman | cds-NP_012906.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:405396-406346:+ | gene-YKL019W_CAT1 | rna-NM_001179585.3_CAT1 | cds-NP_012906.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:401305-402255:+ | gene-YKL019W_CBS1585 | rna-NM_001179585.3_CBS1585 | cds-NP_012906.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:400166-401116:+ | gene-YKL019W_CBS436 | rna-NM_001179585.3_CBS436 | cds-NP_012906.3_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:385461-386411:+ | gene-YKL019W_CBS6412 | rna-NM_001179585.3_CBS6412 | cds-NP_012906.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:401160-402110:+ | gene-YKL019W_CBS6413 | rna-NM_001179585.3_CBS6413 | cds-NP_012906.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:402245-403195:+ | gene-YKL019W_CENPK1137D | rna-NM_001179585.3_CENPK1137D | cds-NP_012906.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:399082-400032:+ | gene-YKL019W_EthanolRed | rna-NM_001179585.3_EthanolRed | cds-NP_012906.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:401172-402122:+ | gene-YKL019W_FaliES1 | rna-NM_001179585.3_FaliES1 | cds-NP_012906.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000142.1:28928-29878:- | gene-YKL019W_JAY291 | rna-NM_001179585.3_JAY291 | cds-NP_012906.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:409603-410553:+ | gene-YKL019W_MUCL30387 | rna-NM_001179585.3_MUCL30387 | cds-NP_012906.3_MUCL30387 | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:405212-406162:+ | gene-YKL019W_MUCL30388 | rna-NM_001179585.3_MUCL30388 | cds-NP_012906.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:400622-401572:+ | gene-YKL019W_MUCL39482 | rna-NM_001179585.3_MUCL39482 | cds-NP_012906.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:406449-407399:+ | gene-YKL019W_MUCL42920 | rna-NM_001179585.3_MUCL42920 | cds-NP_012906.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:402557-403507:+ | gene-YKL019W_NCIM3186 | rna-NM_001179585.3_NCIM3186 | cds-NP_012906.3_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:400814-401764:+ | gene-YKL019W_NCYC1407 | rna-NM_001179585.3_NCYC1407 | cds-NP_012906.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:425504-426454:+ | gene-YKL019W_PE2H3 | rna-NM_001179585.3_PE2H3 | cds-NP_012906.3_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:410248-411198:+ | gene-YKL019W_PE2H4 | rna-NM_001179585.3_PE2H4 | cds-NP_012906.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:402568-403518:+ | gene-YKL019W_S288C | rna-NM_001179585.3_S288C | cds-NP_012906.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000027.1:80846-81796:+ | gene-YKL019W_SA1 | rna-NM_001179585.3_SA1 | cds-NP_012906.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:401271-402221:+ | gene-YKL019W_ThermosaccDry | rna-NM_001179585.3_ThermosaccDry | cds-NP_012906.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:400526-401476:+ | gene-YKL019W_VR1 | rna-NM_001179585.3_VR1 | cds-NP_012906.3_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:399299-400249:+ | gene-YKL019W_ZTW1 | rna-NM_001179585.3_ZTW1 | cds-NP_012906.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:424303-425253:+ | gene-YKL019W_Sparadoxus | rna-NM_001179585.3_Sparadoxus | cds-NP_012906.3_Sparadoxus | 89.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |