Gene name: RAI1
Reference locus (S288C): YGL246C
Gene biotype: protein_coding
Description: Nuclear protein with decapping endonuclease activity; targets mRNAs with unmethylated 7-methylguanosine cap structures and 5'-triphosphates; binds to and stabilizes the exoribonuclease Rat1p; required for pre-rRNA processing; relocalizes to the cytosol in response to hypoxia; homologous to human DOM3Z; Belongs to the DXO/Dom3Z family
Top 10 interactors (score): RAT1 (0.999); RTT103 (0.988); XRN1 (0.97); DCP2 (0.923); GRC3 (0.878); RRP17 (0.861); SKI2 (0.792); NPY1 (0.785); RRP6 (0.779); ABD1 (0.719); REX2 (0.718); NOP15 (0.711); MTR4 (0.705); DDP1 (0.684); CDC123 (0.684); LAS1 (0.669); CEG1 (0.628); SER2 (0.622); CDC48 (0.588); IMP3 (0.582)
Homologues (species, bitscore): DXO (Homo sapiens, 75.1); Dxo (Mus musculus, 79.0); DXO (Danio rerio, 54.3); dxo (Xenopus tropicalis, 91.3); CG9125 (Drosophila melanogaster, 72.8); AT4G17620 (Arabidopsis thaliana, 87.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:39142-40305:- | gene-YGL246C_AKU4011 | rna-NM_001181112.1_AKU4011 | cds-NP_011268.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:31181-32344:- | gene-YGL246C_BG1 | rna-NM_001181112.1_BG1 | cds-NP_011268.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:39497-40660:- | gene-YGL246C_Bruggeman | rna-NM_001181112.1_Bruggeman | cds-NP_011268.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:37569-38732:- | gene-YGL246C_CAT1 | rna-NM_001181112.1_CAT1 | cds-NP_011268.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:43430-44593:- | gene-YGL246C_CBS1585 | rna-NM_001181112.1_CBS1585 | cds-NP_011268.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:38158-39321:- | gene-YGL246C_CBS436 | rna-NM_001181112.1_CBS436 | cds-NP_011268.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:30998-32161:- | gene-YGL246C_CBS6412 | rna-NM_001181112.1_CBS6412 | cds-NP_011268.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:37286-38449:- | gene-YGL246C_CBS6413 | rna-NM_001181112.1_CBS6413 | cds-NP_011268.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:37279-38442:- | gene-YGL246C_CENPK1137D | rna-NM_001181112.1_CENPK1137D | cds-NP_011268.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:30419-31582:- | gene-YGL246C_EthanolRed | rna-NM_001181112.1_EthanolRed | cds-NP_011268.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:30780-31943:- | gene-YGL246C_FaliES1 | rna-NM_001181112.1_FaliES1 | cds-NP_011268.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000079.1:35138-36301:+ | gene-YGL246C_JAY291 | rna-NM_001181112.1_JAY291 | cds-NP_011268.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:39434-40597:- | gene-YGL246C_MUCL30387 | rna-NM_001181112.1_MUCL30387 | cds-NP_011268.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:41587-42750:- | gene-YGL246C_MUCL30388 | rna-NM_001181112.1_MUCL30388 | cds-NP_011268.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:40027-41190:- | gene-YGL246C_MUCL39482 | rna-NM_001181112.1_MUCL39482 | cds-NP_011268.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:42920-44083:- | gene-YGL246C_MUCL42920 | rna-NM_001181112.1_MUCL42920 | cds-NP_011268.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:37617-38780:- | gene-YGL246C_NCIM3186 | rna-NM_001181112.1_NCIM3186 | cds-NP_011268.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:31791-32954:- | gene-YGL246C_NCYC1407 | rna-NM_001181112.1_NCYC1407 | cds-NP_011268.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:33647-34810:- | gene-YGL246C_PE2H3 | rna-NM_001181112.1_PE2H3 | cds-NP_011268.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:33195-34358:- | gene-YGL246C_PE2H4 | rna-NM_001181112.1_PE2H4 | cds-NP_011268.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:37617-38780:- | gene-YGL246C_S288C | rna-NM_001181112.1_S288C | cds-NP_011268.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:336554-337717:+ | gene-YGL246C_SA1 | rna-NM_001181112.1_SA1 | cds-NP_011268.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:31095-32258:- | gene-YGL246C_ThermosaccDry | rna-NM_001181112.1_ThermosaccDry | cds-NP_011268.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:38084-39247:- | gene-YGL246C_VR1 | rna-NM_001181112.1_VR1 | cds-NP_011268.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:30168-31331:- | gene-YGL246C_ZTW1 | rna-NM_001181112.1_ZTW1 | cds-NP_011268.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:38864-40027:- | gene-YGL246C_Sparadoxus | rna-NM_001181112.1_Sparadoxus | cds-NP_011268.1_Sparadoxus | 89.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |