RAD9 (YDR217C)


Gene profile

Gene name: RAD9
Reference locus (S288C): YDR217C
Gene biotype: protein_coding

Description: DNA damage-dependent checkpoint protein; required for cell-cycle arrest in G1/S, intra-S, and G2/M, plays a role in postreplication repair (PRR) pathway; transmits checkpoint signal by activating Rad53p and Chk1p; hyperphosphorylated by Mec1p and Tel1p; multiple cyclin dependent kinase consensus sites and the C-terminal BRCT domain contribute to DNA damage checkpoint activation; Rad9p Chk1 Activating Domain (CAD) is phosphorylated at multiple sites by Cdc28p/Clb2p

Top 10 interactors (score): RTT107 (0.999); DPB11 (0.999); TEL1 (0.999); RAD53 (0.999); SGS1 (0.999); CHK1 (0.999); MEC1 (0.999); MRE11 (0.998); HTA1 (0.998); HTA2 (0.998); RFA1 (0.995); MRC1 (0.995); RAD2 (0.993); DUN1 (0.992); RAD24 (0.992); RAD52 (0.989); CDC13 (0.989); RAD1 (0.987); EXO1 (0.985); RAD17 (0.985)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:856251-860180:- gene-YDR217C_AKU4011 rna-NM_001180525.1_AKU4011 cds-NP_010503.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:265653-269582:+ gene-YDR217C_BG1 rna-NM_001180525.1_BG1 cds-NP_010503.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:888584-892513:- gene-YDR217C_Bruggeman rna-NM_001180525.1_Bruggeman cds-NP_010503.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:875845-879774:- gene-YDR217C_CAT1 rna-NM_001180525.1_CAT1 cds-NP_010503.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:846603-850532:- gene-YDR217C_CBS1585 rna-NM_001180525.1_CBS1585 cds-NP_010503.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:875611-879540:- gene-YDR217C_CBS436 rna-NM_001180525.1_CBS436 cds-NP_010503.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:843362-847291:- gene-YDR217C_CBS6412 rna-NM_001180525.1_CBS6412 cds-NP_010503.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:873961-877890:- gene-YDR217C_CBS6413 rna-NM_001180525.1_CBS6413 cds-NP_010503.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:898353-902282:- gene-YDR217C_CENPK1137D rna-NM_001180525.1_CENPK1137D cds-NP_010503.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:856945-860874:- gene-YDR217C_EthanolRed rna-NM_001180525.1_EthanolRed cds-NP_010503.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:865146-869075:- gene-YDR217C_FaliES1 rna-NM_001180525.1_FaliES1 cds-NP_010503.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000348.1:42499-46428:+ gene-YDR217C_JAY291 rna-NM_001180525.1_JAY291 cds-NP_010503.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:874235-878164:- gene-YDR217C_MUCL30387 rna-NM_001180525.1_MUCL30387 cds-NP_010503.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:862489-866418:- gene-YDR217C_MUCL30388 rna-NM_001180525.1_MUCL30388 cds-NP_010503.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:848012-851941:- gene-YDR217C_MUCL39482 rna-NM_001180525.1_MUCL39482 cds-NP_010503.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:787293-791222:- gene-YDR217C_MUCL42920 rna-NM_001180525.1_MUCL42920 cds-NP_010503.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:899474-903403:- gene-YDR217C_NCIM3186 rna-NM_001180525.1_NCIM3186 cds-NP_010503.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:851677-855606:- gene-YDR217C_NCYC1407 rna-NM_001180525.1_NCYC1407 cds-NP_010503.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:867902-871831:- gene-YDR217C_PE2H3 rna-NM_001180525.1_PE2H3 cds-NP_010503.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:873184-877113:- gene-YDR217C_PE2H4 rna-NM_001180525.1_PE2H4 cds-NP_010503.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:899551-903480:- gene-YDR217C_S288C rna-NM_001180525.1_S288C cds-NP_010503.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000013.1:105658-109587:- gene-YDR217C_SA1 rna-NM_001180525.1_SA1 cds-NP_010503.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:863302-867231:- gene-YDR217C_ThermosaccDry rna-NM_001180525.1_ThermosaccDry cds-NP_010503.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:878507-882436:- gene-YDR217C_VR1 rna-NM_001180525.1_VR1 cds-NP_010503.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000007.1:126019-129948:- gene-YDR217C_ZTW1 rna-NM_001180525.1_ZTW1 cds-NP_010503.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:868454-872391:- gene-YDR217C_Sparadoxus rna-NM_001180525.1_Sparadoxus cds-NP_010503.1_Sparadoxus 85.2 100.0 Unannotated 1 1 0 False False False True False

Additional files