Gene name: RAD9
Reference locus (S288C): YDR217C
Gene biotype: protein_coding
Description: DNA damage-dependent checkpoint protein; required for cell-cycle arrest in G1/S, intra-S, and G2/M, plays a role in postreplication repair (PRR) pathway; transmits checkpoint signal by activating Rad53p and Chk1p; hyperphosphorylated by Mec1p and Tel1p; multiple cyclin dependent kinase consensus sites and the C-terminal BRCT domain contribute to DNA damage checkpoint activation; Rad9p Chk1 Activating Domain (CAD) is phosphorylated at multiple sites by Cdc28p/Clb2p
Top 10 interactors (score): RTT107 (0.999); DPB11 (0.999); TEL1 (0.999); RAD53 (0.999); SGS1 (0.999); CHK1 (0.999); MEC1 (0.999); MRE11 (0.998); HTA1 (0.998); HTA2 (0.998); RFA1 (0.995); MRC1 (0.995); RAD2 (0.993); DUN1 (0.992); RAD24 (0.992); RAD52 (0.989); CDC13 (0.989); RAD1 (0.987); EXO1 (0.985); RAD17 (0.985)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:856251-860180:- | gene-YDR217C_AKU4011 | rna-NM_001180525.1_AKU4011 | cds-NP_010503.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:265653-269582:+ | gene-YDR217C_BG1 | rna-NM_001180525.1_BG1 | cds-NP_010503.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:888584-892513:- | gene-YDR217C_Bruggeman | rna-NM_001180525.1_Bruggeman | cds-NP_010503.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:875845-879774:- | gene-YDR217C_CAT1 | rna-NM_001180525.1_CAT1 | cds-NP_010503.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:846603-850532:- | gene-YDR217C_CBS1585 | rna-NM_001180525.1_CBS1585 | cds-NP_010503.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:875611-879540:- | gene-YDR217C_CBS436 | rna-NM_001180525.1_CBS436 | cds-NP_010503.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:843362-847291:- | gene-YDR217C_CBS6412 | rna-NM_001180525.1_CBS6412 | cds-NP_010503.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:873961-877890:- | gene-YDR217C_CBS6413 | rna-NM_001180525.1_CBS6413 | cds-NP_010503.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:898353-902282:- | gene-YDR217C_CENPK1137D | rna-NM_001180525.1_CENPK1137D | cds-NP_010503.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:856945-860874:- | gene-YDR217C_EthanolRed | rna-NM_001180525.1_EthanolRed | cds-NP_010503.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:865146-869075:- | gene-YDR217C_FaliES1 | rna-NM_001180525.1_FaliES1 | cds-NP_010503.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000348.1:42499-46428:+ | gene-YDR217C_JAY291 | rna-NM_001180525.1_JAY291 | cds-NP_010503.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:874235-878164:- | gene-YDR217C_MUCL30387 | rna-NM_001180525.1_MUCL30387 | cds-NP_010503.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:862489-866418:- | gene-YDR217C_MUCL30388 | rna-NM_001180525.1_MUCL30388 | cds-NP_010503.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:848012-851941:- | gene-YDR217C_MUCL39482 | rna-NM_001180525.1_MUCL39482 | cds-NP_010503.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:787293-791222:- | gene-YDR217C_MUCL42920 | rna-NM_001180525.1_MUCL42920 | cds-NP_010503.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:899474-903403:- | gene-YDR217C_NCIM3186 | rna-NM_001180525.1_NCIM3186 | cds-NP_010503.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:851677-855606:- | gene-YDR217C_NCYC1407 | rna-NM_001180525.1_NCYC1407 | cds-NP_010503.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:867902-871831:- | gene-YDR217C_PE2H3 | rna-NM_001180525.1_PE2H3 | cds-NP_010503.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:873184-877113:- | gene-YDR217C_PE2H4 | rna-NM_001180525.1_PE2H4 | cds-NP_010503.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:899551-903480:- | gene-YDR217C_S288C | rna-NM_001180525.1_S288C | cds-NP_010503.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:105658-109587:- | gene-YDR217C_SA1 | rna-NM_001180525.1_SA1 | cds-NP_010503.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:863302-867231:- | gene-YDR217C_ThermosaccDry | rna-NM_001180525.1_ThermosaccDry | cds-NP_010503.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:878507-882436:- | gene-YDR217C_VR1 | rna-NM_001180525.1_VR1 | cds-NP_010503.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:126019-129948:- | gene-YDR217C_ZTW1 | rna-NM_001180525.1_ZTW1 | cds-NP_010503.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:868454-872391:- | gene-YDR217C_Sparadoxus | rna-NM_001180525.1_Sparadoxus | cds-NP_010503.1_Sparadoxus | 85.2 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |