Gene name: RAD59
Reference locus (S288C): YDL059C
Gene biotype: protein_coding
Description: Protein involved DNA double-strand break repair; repairs breaks in DNA during vegetative growth via recombination and single-strand annealing; anneals complementary single-stranded DNA; forms nuclear foci upon DNA replication stress; required for loading of Rad52p to DSBs; regulates replication fork progression in DNA ligase I-deficient cells; paralog of Rad52p; Belongs to the RAD52 family
Top 10 interactors (score): RAD52 (0.998); RAD51 (0.998); RFA1 (0.994); RAD57 (0.989); SRS2 (0.98); RAD54 (0.979); SGS1 (0.97); RDH54 (0.962); RAD55 (0.955); MEC1 (0.949); MUS81 (0.934); DNL4 (0.93); RAD1 (0.926); DNA2 (0.925); MSH2 (0.925); YKU70 (0.919); RAD27 (0.914); UBC9 (0.908); MSH3 (0.907); EXO1 (0.906)
Homologues (species, bitscore): RAD52 (Homo sapiens, 57.4); Rad52 (Mus musculus, 58.2); rad52 (Danio rerio, 54.7); rad52 (Xenopus tropicalis, 54.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:328816-329532:- | gene-YDL059C_AKU4011 | rna-NM_001180118.1_AKU4011 | cds-NP_010224.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:220496-221212:+ | gene-YDL059C_BG1 | rna-NM_001180118.1_BG1 | cds-NP_010224.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:346605-347321:- | gene-YDL059C_Bruggeman | rna-NM_001180118.1_Bruggeman | cds-NP_010224.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:342976-343692:- | gene-YDL059C_CAT1 | rna-NM_001180118.1_CAT1 | cds-NP_010224.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:327067-327783:- | gene-YDL059C_CBS1585 | rna-NM_001180118.1_CBS1585 | cds-NP_010224.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:343789-344505:- | gene-YDL059C_CBS436 | rna-NM_001180118.1_CBS436 | cds-NP_010224.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:325164-325880:- | gene-YDL059C_CBS6412 | rna-NM_001180118.1_CBS6412 | cds-NP_010224.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:345153-345869:- | gene-YDL059C_CBS6413 | rna-NM_001180118.1_CBS6413 | cds-NP_010224.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:343059-343775:- | gene-YDL059C_CENPK1137D | rna-NM_001180118.1_CENPK1137D | cds-NP_010224.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:339619-340335:- | gene-YDL059C_EthanolRed | rna-NM_001180118.1_EthanolRed | cds-NP_010224.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:345866-346582:- | gene-YDL059C_FaliES1 | rna-NM_001180118.1_FaliES1 | cds-NP_010224.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000240.1:233-950:- | gene-YDL059C_JAY291 | rna-NM_001180118.1_JAY291 | cds-NP_010224.1_JAY291 | 99.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:343996-344712:- | gene-YDL059C_MUCL30387 | rna-NM_001180118.1_MUCL30387 | cds-NP_010224.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:335122-335838:- | gene-YDL059C_MUCL30388 | rna-NM_001180118.1_MUCL30388 | cds-NP_010224.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:328178-328894:- | gene-YDL059C_MUCL39482 | rna-NM_001180118.1_MUCL39482 | cds-NP_010224.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:250192-250908:- | gene-YDL059C_MUCL42920 | rna-NM_001180118.1_MUCL42920 | cds-NP_010224.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:344160-344876:- | gene-YDL059C_NCIM3186 | rna-NM_001180118.1_NCIM3186 | cds-NP_010224.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:328202-328918:- | gene-YDL059C_NCYC1407 | rna-NM_001180118.1_NCYC1407 | cds-NP_010224.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:335019-335735:- | gene-YDL059C_PE2H3 | rna-NM_001180118.1_PE2H3 | cds-NP_010224.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:335019-335735:- | gene-YDL059C_PE2H4 | rna-NM_001180118.1_PE2H4 | cds-NP_010224.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:344237-344953:- | gene-YDL059C_S288C | rna-NM_001180118.1_S288C | cds-NP_010224.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:89981-90697:+ | gene-YDL059C_SA1 | rna-NM_001180118.1_SA1 | cds-NP_010224.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:345318-346034:- | gene-YDL059C_ThermosaccDry | rna-NM_001180118.1_ThermosaccDry | cds-NP_010224.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:347907-348623:- | gene-YDL059C_VR1 | rna-NM_001180118.1_VR1 | cds-NP_010224.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:343253-343969:- | gene-YDL059C_ZTW1 | rna-NM_001180118.1_ZTW1 | cds-NP_010224.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:345384-346100:- | gene-YDL059C_Sparadoxus | rna-NM_001180118.1_Sparadoxus | cds-NP_010224.1_Sparadoxus | 90.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |