Gene name: RAD50
Reference locus (S288C): YNL250W
Gene biotype: protein_coding
Description: DNA repair protein RAD50; Subunit of MRX complex with Mre11p and Xrs2p; complex is involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining; forms nuclear foci upon DNA replication stress; Belongs to the SMC family. RAD50 subfamily
Top 10 interactors (score): MRE11 (0.999); TEL1 (0.997); XRS2 (0.992); RTT107 (0.992); YKU70 (0.987); SMC3 (0.986); SPO11 (0.982); RAD52 (0.978); MEC1 (0.974); SGS1 (0.973); RAD51 (0.971); SMC1 (0.963); EXO1 (0.959); SAE2 (0.94); RAD27 (0.908); SRS2 (0.895); YKU80 (0.894); RAD9 (0.891); SNU66 (0.886); RRM3 (0.87)
Homologues (species, bitscore): RAD50 (Homo sapiens, 452.2); Rad50 (Mus musculus, 454.5); rad50 (Danio rerio, 466.8); rad50 (Xenopus tropicalis, 473.0); rad50 (Drosophila melanogaster, 429.9); rad-50 (Caenorhabditis elegans, 302.8); RAD50 (Arabidopsis thaliana, 446.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:169194-173132:+ | gene-YNL250W_AKU4011 | rna-NM_001183088.1_AKU4011 | cds-NP_014149.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:73138-77076:+ | gene-YNL250W_BG1 | rna-NM_001183088.1_BG1 | cds-NP_014149.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:179002-182940:+ | gene-YNL250W_Bruggeman | rna-NM_001183088.1_Bruggeman | cds-NP_014149.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:186297-190235:+ | gene-YNL250W_CAT1 | rna-NM_001183088.1_CAT1 | cds-NP_014149.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:169591-173529:+ | gene-YNL250W_CBS1585 | rna-NM_001183088.1_CBS1585 | cds-NP_014149.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:164682-168620:+ | gene-YNL250W_CBS436 | rna-NM_001183088.1_CBS436 | cds-NP_014149.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:166005-169943:+ | gene-YNL250W_CBS6412 | rna-NM_001183088.1_CBS6412 | cds-NP_014149.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:166273-170211:+ | gene-YNL250W_CBS6413 | rna-NM_001183088.1_CBS6413 | cds-NP_014149.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:169221-173159:+ | gene-YNL250W_CENPK1137D | rna-NM_001183088.1_CENPK1137D | cds-NP_014149.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:166851-170789:+ | gene-YNL250W_EthanolRed | rna-NM_001183088.1_EthanolRed | cds-NP_014149.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:161586-165524:+ | gene-YNL250W_FaliES1 | rna-NM_001183088.1_FaliES1 | cds-NP_014149.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:72733-76671:+ | gene-YNL250W_JAY291 | rna-NM_001183088.1_JAY291 | cds-NP_014149.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:174784-178722:+ | gene-YNL250W_MUCL30387 | rna-NM_001183088.1_MUCL30387 | cds-NP_014149.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:173368-177306:+ | gene-YNL250W_MUCL30388 | rna-NM_001183088.1_MUCL30388 | cds-NP_014149.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:167081-171019:+ | gene-YNL250W_MUCL39482 | rna-NM_001183088.1_MUCL39482 | cds-NP_014149.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:169339-173277:+ | gene-YNL250W_MUCL42920 | rna-NM_001183088.1_MUCL42920 | cds-NP_014149.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:175379-179317:+ | gene-YNL250W_NCIM3186 | rna-NM_001183088.1_NCIM3186 | cds-NP_014149.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:169173-173111:+ | gene-YNL250W_NCYC1407 | rna-NM_001183088.1_NCYC1407 | cds-NP_014149.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:166076-170014:+ | gene-YNL250W_PE2H3 | rna-NM_001183088.1_PE2H3 | cds-NP_014149.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:165464-169402:+ | gene-YNL250W_PE2H4 | rna-NM_001183088.1_PE2H4 | cds-NP_014149.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:175410-179348:+ | gene-YNL250W_S288C | rna-NM_001183088.1_S288C | cds-NP_014149.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:72945-76883:- | gene-YNL250W_SA1 | rna-NM_001183088.1_SA1 | cds-NP_014149.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:162442-166380:+ | gene-YNL250W_ThermosaccDry | rna-NM_001183088.1_ThermosaccDry | cds-NP_014149.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:181333-185271:+ | gene-YNL250W_VR1 | rna-NM_001183088.1_VR1 | cds-NP_014149.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:72764-76702:+ | gene-YNL250W_ZTW1 | rna-NM_001183088.1_ZTW1 | cds-NP_014149.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:172698-176636:+ | gene-YNL250W_Sparadoxus | rna-NM_001183088.1_Sparadoxus | cds-NP_014149.1_Sparadoxus | 90.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |