Gene name: RAD5
Reference locus (S288C): YLR032W
Gene biotype: protein_coding
Description: DNA repair protein RAD5; DNA helicase/Ubiquitin ligase; involved in error-free DNA damage tolerance (DDT), replication fork regression during postreplication repair by template switching, error-prone translesion synthesis; promotes synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p; forms nuclear foci upon DNA replication stress; associates with native telomeres, cooperates with homologous recombination in senescent cells; human homolog HLTF can complement yeast null mutant
Top 10 interactors (score): MMS2 (0.999); UBC13 (0.999); RAD18 (0.999); REV1 (0.998); SRS2 (0.997); POL30 (0.997); RAD51 (0.996); REV3 (0.992); RAD52 (0.991); RAD6 (0.991); SGS1 (0.986); MPH1 (0.981); RAD30 (0.976); SIZ1 (0.956); MUS81 (0.953); RAD9 (0.948); RAD1 (0.947); ELG1 (0.935); POL32 (0.934); MGS1 (0.928)
Homologues (species, bitscore): HLTF (Homo sapiens, 293.9); Hltf (Mus musculus, 294.7); hltf (Danio rerio, 284.6); HLTF (Xenopus tropicalis, 297.0); lds (Drosophila melanogaster, 228.8); T23H2.3 (Caenorhabditis elegans, 180.6); AT5G43530 (Arabidopsis thaliana, 411.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:192921-196430:+ | gene-YLR032W_AKU4011 | rna-NM_001181919.1_AKU4011 | cds-NP_013132.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:156197-159709:+ | gene-YLR032W_BG1 | rna-NM_001181919.1_BG1 | cds-NP_013132.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:203314-206823:+ | gene-YLR032W_Bruggeman | rna-NM_001181919.1_Bruggeman | cds-NP_013132.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:203642-207151:+ | gene-YLR032W_CAT1 | rna-NM_001181919.1_CAT1 | cds-NP_013132.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:200547-204056:+ | gene-YLR032W_CBS1585 | rna-NM_001181919.1_CBS1585 | cds-NP_013132.1_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:191182-194691:+ | gene-YLR032W_CBS436 | rna-NM_001181919.1_CBS436 | cds-NP_013132.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:198956-202465:+ | gene-YLR032W_CBS6412 | rna-NM_001181919.1_CBS6412 | cds-NP_013132.1_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:200809-204318:+ | gene-YLR032W_CBS6413 | rna-NM_001181919.1_CBS6413 | cds-NP_013132.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:190223-193729:+ | gene-YLR032W_CENPK1137D | rna-NM_001181919.1_CENPK1137D | cds-NP_013132.1_CENPK1137D | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:192932-196441:+ | gene-YLR032W_EthanolRed | rna-NM_001181919.1_EthanolRed | cds-NP_013132.1_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:192842-196351:+ | gene-YLR032W_FaliES1 | rna-NM_001181919.1_FaliES1 | cds-NP_013132.1_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000431.1:36697-40209:+ | gene-YLR032W_JAY291 | rna-NM_001181919.1_JAY291 | cds-NP_013132.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:200668-204180:+ | gene-YLR032W_MUCL30387 | rna-NM_001181919.1_MUCL30387 | cds-NP_013132.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:207540-211178:+ | gene-YLR032W_MUCL30388 | rna-NM_001181919.1_MUCL30388 | cds-NP_013132.1_MUCL30388 | 96.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:201042-204551:+ | gene-YLR032W_MUCL39482 | rna-NM_001181919.1_MUCL39482 | cds-NP_013132.1_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:200945-204454:+ | gene-YLR032W_MUCL42920 | rna-NM_001181919.1_MUCL42920 | cds-NP_013132.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:204965-208474:+ | gene-YLR032W_NCIM3186 | rna-NM_001181919.1_NCIM3186 | cds-NP_013132.1_NCIM3186 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:193100-196609:+ | gene-YLR032W_NCYC1407 | rna-NM_001181919.1_NCYC1407 | cds-NP_013132.1_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:198980-202489:+ | gene-YLR032W_PE2H3 | rna-NM_001181919.1_PE2H3 | cds-NP_013132.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:198721-202230:+ | gene-YLR032W_PE2H4 | rna-NM_001181919.1_PE2H4 | cds-NP_013132.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:204991-208500:+ | gene-YLR032W_S288C | rna-NM_001181919.1_S288C | cds-NP_013132.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000046.1:36827-40333:+ | gene-YLR032W_SA1 | rna-NM_001181919.1_SA1 | cds-NP_013132.1_SA1 | 98.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:193008-196517:+ | gene-YLR032W_ThermosaccDry | rna-NM_001181919.1_ThermosaccDry | cds-NP_013132.1_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:206430-209939:+ | gene-YLR032W_VR1 | rna-NM_001181919.1_VR1 | cds-NP_013132.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:192373-195882:+ | gene-YLR032W_ZTW1 | rna-NM_001181919.1_ZTW1 | cds-NP_013132.1_ZTW1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:201167-204679:+ | gene-YLR032W_Sparadoxus | rna-NM_001181919.1_Sparadoxus | cds-NP_013132.1_Sparadoxus | 89.1 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |