Gene name: RAD4
Reference locus (S288C): YER162C
Gene biotype: protein_coding
Description: Xeroderma pigmentosum group c-complementing protein; Protein that recognizes and binds damaged DNA (with Rad23p) during NER; subunit of Nuclear Excision Repair Factor 2 (NEF2); also involved, with Rad23p, in turnover of ubiquitylated proteins; Rad4p-Rad23p heterodimer binds to promoters of DNA damage response genes to repress their transcription in the absence of DNA damage; NER stands for nucleotide excision repair; Belongs to the XPC family
Top 10 interactors (score): RAD14 (0.999); RAD2 (0.999); TFB1 (0.999); RAD7 (0.999); RAD23 (0.999); RAD16 (0.995); RAD10 (0.995); CDC31 (0.994); RAD1 (0.994); RAD3 (0.993); SSL2 (0.988); RAD26 (0.985); SSL1 (0.972); SNF5 (0.952); ABF1 (0.924); PNG1 (0.915); SHU2 (0.914); SHU1 (0.913); PSY3 (0.912); CSM2 (0.912)
Homologues (species, bitscore): XPC (Homo sapiens, 115.2); Xpc (Mus musculus, 127.9); xpc (Danio rerio, 104.0); XPC (Xenopus tropicalis, 101.7); mus210 (Drosophila melanogaster, 125.9); xpc-1 (Caenorhabditis elegans, 122.5); RAD4 (Arabidopsis thaliana, 104.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:482184-484448:- | gene-YER162C_AKU4011 | rna-NM_001179052.4_AKU4011 | cds-NP_011089.4_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000176.1:48925-51189:+ | gene-YER162C_BG1 | rna-NM_001179052.4_BG1 | cds-NP_011089.4_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:494893-497157:- | gene-YER162C_Bruggeman | rna-NM_001179052.4_Bruggeman | cds-NP_011089.4_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:481490-483754:- | gene-YER162C_CAT1 | rna-NM_001179052.4_CAT1 | cds-NP_011089.4_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:481993-484257:- | gene-YER162C_CBS1585 | rna-NM_001179052.4_CBS1585 | cds-NP_011089.4_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:491876-494140:- | gene-YER162C_CBS436 | rna-NM_001179052.4_CBS436 | cds-NP_011089.4_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:479969-482233:- | gene-YER162C_CBS6412 | rna-NM_001179052.4_CBS6412 | cds-NP_011089.4_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:488539-490803:- | gene-YER162C_CBS6413 | rna-NM_001179052.4_CBS6413 | cds-NP_011089.4_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:498402-500666:- | gene-YER162C_CENPK1137D | rna-NM_001179052.4_CENPK1137D | cds-NP_011089.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:488132-490396:- | gene-YER162C_EthanolRed | rna-NM_001179052.4_EthanolRed | cds-NP_011089.4_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:489068-491332:- | gene-YER162C_FaliES1 | rna-NM_001179052.4_FaliES1 | cds-NP_011089.4_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000169.1:48576-50840:+ | gene-YER162C_JAY291 | rna-NM_001179052.4_JAY291 | cds-NP_011089.4_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:482233-484497:- | gene-YER162C_MUCL30387 | rna-NM_001179052.4_MUCL30387 | cds-NP_011089.4_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:485141-487405:- | gene-YER162C_MUCL30388 | rna-NM_001179052.4_MUCL30388 | cds-NP_011089.4_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:477950-480214:- | gene-YER162C_MUCL39482 | rna-NM_001179052.4_MUCL39482 | cds-NP_011089.4_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:492456-494720:- | gene-YER162C_MUCL42920 | rna-NM_001179052.4_MUCL42920 | cds-NP_011089.4_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:500629-502893:- | gene-YER162C_NCIM3186 | rna-NM_001179052.4_NCIM3186 | cds-NP_011089.4_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:487407-489671:- | gene-YER162C_NCYC1407 | rna-NM_001179052.4_NCYC1407 | cds-NP_011089.4_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:503309-505573:- | gene-YER162C_PE2H3 | rna-NM_001179052.4_PE2H3 | cds-NP_011089.4_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:493250-495514:- | gene-YER162C_PE2H4 | rna-NM_001179052.4_PE2H4 | cds-NP_011089.4_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:500630-502894:- | gene-YER162C_S288C | rna-NM_001179052.4_S288C | cds-NP_011089.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000030.1:52795-55059:- | gene-YER162C_SA1 | rna-NM_001179052.4_SA1 | cds-NP_011089.4_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:489868-492132:- | gene-YER162C_ThermosaccDry | rna-NM_001179052.4_ThermosaccDry | cds-NP_011089.4_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:483155-485419:- | gene-YER162C_VR1 | rna-NM_001179052.4_VR1 | cds-NP_011089.4_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000011.1:2721-4985:- | gene-YER162C_ZTW1 | rna-NM_001179052.4_ZTW1 | cds-NP_011089.4_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:491075-493345:- | gene-YER162C_Sparadoxus | rna-NM_001179052.4_Sparadoxus | cds-NP_011089.4_Sparadoxus | 88.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |