Gene name: RAD30
Reference locus (S288C): YDR419W
Gene biotype: protein_coding
Description: DNA polymerase eta; involved in translesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; involved in formation of post-replicative damage-induced genome-wide cohesion; may also have a role in protection against mitochondrial mutagenesis; mutations in human pol eta are responsible for XPV
Top 10 interactors (score): REV1 (0.999); POL30 (0.999); REV3 (0.999); RAD18 (0.998); PDS5 (0.983); MMS2 (0.978); RAD5 (0.976); OGG1 (0.974); POL3 (0.972); RAD14 (0.963); SMC3 (0.962); RAD6 (0.953); MSH6 (0.941); UBC13 (0.939); RAD51 (0.938); POL31 (0.926); REV7 (0.922); POL4 (0.916); RPS31 (0.913); POL2 (0.909)
Homologues (species, bitscore): POLH (Homo sapiens, 99.4); Polh (Mus musculus, 99.0); polh (Danio rerio, 97.8); poli (Xenopus tropicalis, 61.2); DNApol-eta (Drosophila melanogaster, 83.2); polh-1 (Caenorhabditis elegans, 81.6); POLH (Arabidopsis thaliana, 95.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1243307-1245205:+ | gene-YDR419W_AKU4011 | rna-NM_001180727.3_AKU4011 | cds-NP_010707.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:121813-123711:+ | gene-YDR419W_BG1 | rna-NM_001180727.3_BG1 | cds-NP_010707.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1274209-1276107:+ | gene-YDR419W_Bruggeman | rna-NM_001180727.3_Bruggeman | cds-NP_010707.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1252768-1254666:+ | gene-YDR419W_CAT1 | rna-NM_001180727.3_CAT1 | cds-NP_010707.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1238227-1240125:+ | gene-YDR419W_CBS1585 | rna-NM_001180727.3_CBS1585 | cds-NP_010707.3_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1257106-1259004:+ | gene-YDR419W_CBS436 | rna-NM_001180727.3_CBS436 | cds-NP_010707.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1234281-1236179:+ | gene-YDR419W_CBS6412 | rna-NM_001180727.3_CBS6412 | cds-NP_010707.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1256136-1258034:+ | gene-YDR419W_CBS6413 | rna-NM_001180727.3_CBS6413 | cds-NP_010707.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1301833-1303731:+ | gene-YDR419W_CENPK1137D | rna-NM_001180727.3_CENPK1137D | cds-NP_010707.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1247695-1249593:+ | gene-YDR419W_EthanolRed | rna-NM_001180727.3_EthanolRed | cds-NP_010707.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1251002-1252900:+ | gene-YDR419W_FaliES1 | rna-NM_001180727.3_FaliES1 | cds-NP_010707.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000181.1:2590-4488:- | gene-YDR419W_JAY291 | rna-NM_001180727.3_JAY291 | cds-NP_010707.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1257770-1259668:+ | gene-YDR419W_MUCL30387 | rna-NM_001180727.3_MUCL30387 | cds-NP_010707.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1239877-1241775:+ | gene-YDR419W_MUCL30388 | rna-NM_001180727.3_MUCL30388 | cds-NP_010707.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1229555-1231453:+ | gene-YDR419W_MUCL39482 | rna-NM_001180727.3_MUCL39482 | cds-NP_010707.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1172255-1174153:+ | gene-YDR419W_MUCL42920 | rna-NM_001180727.3_MUCL42920 | cds-NP_010707.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1303097-1304995:+ | gene-YDR419W_NCIM3186 | rna-NM_001180727.3_NCIM3186 | cds-NP_010707.3_NCIM3186 | 98.1 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1243527-1245425:+ | gene-YDR419W_NCYC1407 | rna-NM_001180727.3_NCYC1407 | cds-NP_010707.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1253682-1255580:+ | gene-YDR419W_PE2H3 | rna-NM_001180727.3_PE2H3 | cds-NP_010707.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1259250-1261148:+ | gene-YDR419W_PE2H4 | rna-NM_001180727.3_PE2H4 | cds-NP_010707.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1303174-1305072:+ | gene-YDR419W_S288C | rna-NM_001180727.3_S288C | cds-NP_010707.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000071.1:2715-4613:- | gene-YDR419W_SA1 | rna-NM_001180727.3_SA1 | cds-NP_010707.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1255264-1257162:+ | gene-YDR419W_ThermosaccDry | rna-NM_001180727.3_ThermosaccDry | cds-NP_010707.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1270486-1272384:+ | gene-YDR419W_VR1 | rna-NM_001180727.3_VR1 | cds-NP_010707.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:298076-299974:+ | gene-YDR419W_ZTW1 | rna-NM_001180727.3_ZTW1 | cds-NP_010707.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1250542-1252440:+ | gene-YDR419W_Sparadoxus | rna-NM_001180727.3_Sparadoxus | cds-NP_010707.3_Sparadoxus | 88.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |