Gene name: RAD3
Reference locus (S288C): YER171W
Gene biotype: protein_coding
Description: 5' to 3' DNA helicase; involved in nucleotide excision repair and transcription; subunit of RNA polII initiation factor TFIIH and of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPD protein; mutant has aneuploidy tolerance; protein abundance increases in response to DNA replication stress; Belongs to the helicase family. RAD3/XPD subfamily
Top 10 interactors (score): TFA1 (0.999); TFB2 (0.999); TFB5 (0.999); TFB1 (0.999); CCL1 (0.999); RAD2 (0.999); TFB3 (0.999); SSL1 (0.999); KIN28 (0.999); CIA2 (0.999); MET18 (0.999); SSL2 (0.999); TFB4 (0.999); RAD14 (0.998); TFA2 (0.998); TFG1 (0.998); RAD10 (0.996); RAD4 (0.993); RPO21 (0.992); RAD1 (0.991)
Homologues (species, bitscore): ERCC2 (Homo sapiens, 835.9); Ercc2 (Mus musculus, 836.6); ercc2 (Danio rerio, 853.6); ercc2 (Xenopus tropicalis, 716.1); Xpd (Drosophila melanogaster, 859.0); Y50D7A.2 (Caenorhabditis elegans, 615.1); UVH6 (Arabidopsis thaliana, 785.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:508604-510940:+ | gene-YER171W_AKU4011 | rna-NM_001179061.3_AKU4011 | cds-NP_011098.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000176.1:22424-24760:- | gene-YER171W_BG1 | rna-NM_001179061.3_BG1 | cds-NP_011098.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:521346-523682:+ | gene-YER171W_Bruggeman | rna-NM_001179061.3_Bruggeman | cds-NP_011098.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:507938-510274:+ | gene-YER171W_CAT1 | rna-NM_001179061.3_CAT1 | cds-NP_011098.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:508411-510747:+ | gene-YER171W_CBS1585 | rna-NM_001179061.3_CBS1585 | cds-NP_011098.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:518306-520642:+ | gene-YER171W_CBS436 | rna-NM_001179061.3_CBS436 | cds-NP_011098.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:506388-508724:+ | gene-YER171W_CBS6412 | rna-NM_001179061.3_CBS6412 | cds-NP_011098.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:514957-517293:+ | gene-YER171W_CBS6413 | rna-NM_001179061.3_CBS6413 | cds-NP_011098.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:524851-527187:+ | gene-YER171W_CENPK1137D | rna-NM_001179061.3_CENPK1137D | cds-NP_011098.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:514578-516914:+ | gene-YER171W_EthanolRed | rna-NM_001179061.3_EthanolRed | cds-NP_011098.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:515514-517850:+ | gene-YER171W_FaliES1 | rna-NM_001179061.3_FaliES1 | cds-NP_011098.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000169.1:22056-24392:- | gene-YER171W_JAY291 | rna-NM_001179061.3_JAY291 | cds-NP_011098.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:508663-510999:+ | gene-YER171W_MUCL30387 | rna-NM_001179061.3_MUCL30387 | cds-NP_011098.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:511579-513915:+ | gene-YER171W_MUCL30388 | rna-NM_001179061.3_MUCL30388 | cds-NP_011098.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:504369-506705:+ | gene-YER171W_MUCL39482 | rna-NM_001179061.3_MUCL39482 | cds-NP_011098.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:518895-521231:+ | gene-YER171W_MUCL42920 | rna-NM_001179061.3_MUCL42920 | cds-NP_011098.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:527081-529417:+ | gene-YER171W_NCIM3186 | rna-NM_001179061.3_NCIM3186 | cds-NP_011098.3_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:513824-516160:+ | gene-YER171W_NCYC1407 | rna-NM_001179061.3_NCYC1407 | cds-NP_011098.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:529757-532093:+ | gene-YER171W_PE2H3 | rna-NM_001179061.3_PE2H3 | cds-NP_011098.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:519698-522034:+ | gene-YER171W_PE2H4 | rna-NM_001179061.3_PE2H4 | cds-NP_011098.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:527082-529418:+ | gene-YER171W_S288C | rna-NM_001179061.3_S288C | cds-NP_011098.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000030.1:79235-81571:+ | gene-YER171W_SA1 | rna-NM_001179061.3_SA1 | cds-NP_011098.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:516314-518650:+ | gene-YER171W_ThermosaccDry | rna-NM_001179061.3_ThermosaccDry | cds-NP_011098.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:509603-511939:+ | gene-YER171W_VR1 | rna-NM_001179061.3_VR1 | cds-NP_011098.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000011.1:29161-31497:+ | gene-YER171W_ZTW1 | rna-NM_001179061.3_ZTW1 | cds-NP_011098.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:517539-519869:+ | gene-YER171W_Sparadoxus | rna-NM_001179061.3_Sparadoxus | cds-NP_011098.3_Sparadoxus | 92.6 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |