Gene name: RAD27
Reference locus (S288C): YKL113C
Gene biotype: protein_coding
Description: Flap endonuclease 1; 5' to 3' exonuclease, 5' flap endonuclease; required for Okazaki fragment processing and maturation, for long-patch base-excision repair and large loop repair (LLR), ribonucleotide excision repair; member of the S. pombe RAD2/FEN1 family; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): CDC9 (0.999); DNA2 (0.999); MSH6 (0.999); POL30 (0.999); POL3 (0.999); POL31 (0.999); POL1 (0.998); SGS1 (0.998); RAD1 (0.997); POL12 (0.997); MSH2 (0.996); PRI2 (0.995); TOP3 (0.995); RAD51 (0.994); RNH201 (0.994); CTF4 (0.994); PRI1 (0.993); MUS81 (0.993); RAD52 (0.99); RFA1 (0.989)
Homologues (species, bitscore): FEN1 (Homo sapiens, 434.9); Fen1 (Mus musculus, 436.8); fen1 (Danio rerio, 426.8); fen1 (Xenopus tropicalis, 419.9); Fen1 (Drosophila melanogaster, 422.2); crn-1 (Caenorhabditis elegans, 409.5); AT5G26680 (Arabidopsis thaliana, 360.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:211304-212452:- | gene-YKL113C_AKU4011 | rna-NM_001179679.1_AKU4011 | cds-NP_012809.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:188428-189576:- | gene-YKL113C_BG1 | rna-NM_001179679.1_BG1 | cds-NP_012809.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:229219-230367:- | gene-YKL113C_Bruggeman | rna-NM_001179679.1_Bruggeman | cds-NP_012809.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:224274-225422:- | gene-YKL113C_CAT1 | rna-NM_001179679.1_CAT1 | cds-NP_012809.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:223535-224683:- | gene-YKL113C_CBS1585 | rna-NM_001179679.1_CBS1585 | cds-NP_012809.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:222124-223272:- | gene-YKL113C_CBS436 | rna-NM_001179679.1_CBS436 | cds-NP_012809.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:208166-209314:- | gene-YKL113C_CBS6412 | rna-NM_001179679.1_CBS6412 | cds-NP_012809.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:224000-225148:- | gene-YKL113C_CBS6413 | rna-NM_001179679.1_CBS6413 | cds-NP_012809.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:224369-225517:- | gene-YKL113C_CENPK1137D | rna-NM_001179679.1_CENPK1137D | cds-NP_012809.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:221981-223129:- | gene-YKL113C_EthanolRed | rna-NM_001179679.1_EthanolRed | cds-NP_012809.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:222794-223942:- | gene-YKL113C_FaliES1 | rna-NM_001179679.1_FaliES1 | cds-NP_012809.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000357.1:45142-46290:- | gene-YKL113C_JAY291 | rna-NM_001179679.1_JAY291 | cds-NP_012809.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:231031-232179:- | gene-YKL113C_MUCL30387 | rna-NM_001179679.1_MUCL30387 | cds-NP_012809.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:225410-226558:- | gene-YKL113C_MUCL30388 | rna-NM_001179679.1_MUCL30388 | cds-NP_012809.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:223331-224479:- | gene-YKL113C_MUCL39482 | rna-NM_001179679.1_MUCL39482 | cds-NP_012809.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:227706-228854:- | gene-YKL113C_MUCL42920 | rna-NM_001179679.1_MUCL42920 | cds-NP_012809.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:224716-225864:- | gene-YKL113C_NCIM3186 | rna-NM_001179679.1_NCIM3186 | cds-NP_012809.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:223512-224660:- | gene-YKL113C_NCYC1407 | rna-NM_001179679.1_NCYC1407 | cds-NP_012809.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:230614-231762:- | gene-YKL113C_PE2H3 | rna-NM_001179679.1_PE2H3 | cds-NP_012809.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:226894-228042:- | gene-YKL113C_PE2H4 | rna-NM_001179679.1_PE2H4 | cds-NP_012809.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:224727-225875:- | gene-YKL113C_S288C | rna-NM_001179679.1_S288C | cds-NP_012809.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:140853-142001:- | gene-YKL113C_SA1 | rna-NM_001179679.1_SA1 | cds-NP_012809.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:223494-224642:- | gene-YKL113C_ThermosaccDry | rna-NM_001179679.1_ThermosaccDry | cds-NP_012809.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:222865-224013:- | gene-YKL113C_VR1 | rna-NM_001179679.1_VR1 | cds-NP_012809.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:222068-223216:- | gene-YKL113C_ZTW1 | rna-NM_001179679.1_ZTW1 | cds-NP_012809.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:239049-240197:- | gene-YKL113C_Sparadoxus | rna-NM_001179679.1_Sparadoxus | cds-NP_012809.1_Sparadoxus | 92.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |