Gene name: RAD18
Reference locus (S288C): YCR066W
Gene biotype: protein_coding
Description: Postreplication repair E3 ubiquitin-protein ligase RAD18; E3 ubiquitin ligase; forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair; SUMO-targeted ubiquitin ligase (STUbl) that contains a SUMO-interacting motif (SIM) which stimulates its ubiquitin ligase activity towards the sumoylated form of PCNA
Top 10 interactors (score): RAD5 (0.999); POL30 (0.999); RAD6 (0.999); RAD30 (0.998); RAD51 (0.997); REV3 (0.996); RAD52 (0.995); UBC13 (0.994); SRS2 (0.992); MMS2 (0.991); RAD9 (0.983); SIZ1 (0.983); REV1 (0.982); SGS1 (0.977); UBI4 (0.972); RAD1 (0.964); UBC9 (0.964); MGS1 (0.956); ULS1 (0.951); IRC20 (0.925)
Homologues (species, bitscore): RAD18 (Homo sapiens, 95.5); Rad18 (Mus musculus, 98.2); rad18 (Danio rerio, 84.7); RAD18 (Xenopus tropicalis, 89.4); T02C1.1 (Caenorhabditis elegans, 52.4); COP1 (Arabidopsis thaliana, 62.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:225969-227432:+ | gene-YCR066W_AKU4011 | rna-NM_001178777.1_AKU4011 | cds-NP_009992.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000067.1:84690-86153:+ | gene-YCR066W_BG1 | rna-NM_001178777.1_BG1 | cds-NP_009992.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:221927-223390:+ | gene-YCR066W_Bruggeman | rna-NM_001178777.1_Bruggeman | cds-NP_009992.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:233295-234758:+ | gene-YCR066W_CAT1 | rna-NM_001178777.1_CAT1 | cds-NP_009992.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:220748-222211:+ | gene-YCR066W_CBS1585 | rna-NM_001178777.1_CBS1585 | cds-NP_009992.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:232632-234095:+ | gene-YCR066W_CBS436 | rna-NM_001178777.1_CBS436 | cds-NP_009992.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:212488-213951:+ | gene-YCR066W_CBS6412 | rna-NM_001178777.1_CBS6412 | cds-NP_009992.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:226866-228329:+ | gene-YCR066W_CBS6413 | rna-NM_001178777.1_CBS6413 | cds-NP_009992.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:230691-232154:+ | gene-YCR066W_CENPK1137D | rna-NM_001178777.1_CENPK1137D | cds-NP_009992.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:221933-223396:+ | gene-YCR066W_EthanolRed | rna-NM_001178777.1_EthanolRed | cds-NP_009992.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:227098-228561:+ | gene-YCR066W_FaliES1 | rna-NM_001178777.1_FaliES1 | cds-NP_009992.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000323.1:60108-61571:- | gene-YCR066W_JAY291 | rna-NM_001178777.1_JAY291 | cds-NP_009992.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:218899-220362:+ | gene-YCR066W_MUCL30387 | rna-NM_001178777.1_MUCL30387 | cds-NP_009992.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:219223-220686:+ | gene-YCR066W_MUCL30388 | rna-NM_001178777.1_MUCL30388 | cds-NP_009992.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:227321-228784:+ | gene-YCR066W_MUCL39482 | rna-NM_001178777.1_MUCL39482 | cds-NP_009992.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:223758-225221:+ | gene-YCR066W_MUCL42920 | rna-NM_001178777.1_MUCL42920 | cds-NP_009992.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:231132-232595:+ | gene-YCR066W_NCIM3186 | rna-NM_001178777.1_NCIM3186 | cds-NP_009992.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:228180-229643:+ | gene-YCR066W_NCYC1407 | rna-NM_001178777.1_NCYC1407 | cds-NP_009992.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:242815-244278:+ | gene-YCR066W_PE2H3 | rna-NM_001178777.1_PE2H3 | cds-NP_009992.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:231366-232829:+ | gene-YCR066W_PE2H4 | rna-NM_001178777.1_PE2H4 | cds-NP_009992.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:231500-232963:+ | gene-YCR066W_S288C | rna-NM_001178777.1_S288C | cds-NP_009992.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000044.1:31393-32856:+ | gene-YCR066W_SA1 | rna-NM_001178777.1_SA1 | cds-NP_009992.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:227082-228545:+ | gene-YCR066W_ThermosaccDry | rna-NM_001178777.1_ThermosaccDry | cds-NP_009992.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:238351-239814:+ | gene-YCR066W_VR1 | rna-NM_001178777.1_VR1 | cds-NP_009992.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:224896-226359:+ | gene-YCR066W_ZTW1 | rna-NM_001178777.1_ZTW1 | cds-NP_009992.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:259092-260555:+ | gene-YCR066W_Sparadoxus | rna-NM_001178777.1_Sparadoxus | cds-NP_009992.1_Sparadoxus | 87.4 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |