QRI7 (YDL104C)


Gene profile

Gene name: QRI7
Reference locus (S288C): YDL104C
Gene biotype: protein_coding

Description: tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Protein involved in threonylcarbamoyl adenosine biosynthesis; Sua5p and Qri7p are necessary and sufficient for RNA t6A modification in vitro; highly conserved mitochondrial protein; essential for t6A modification of mitochondrial tRNAs that decode ANN codons; similar to Kae1p and E. coli YgjD, both of which are also required for tRNA t6A modification; when directed to the cytoplasm, complements the essential function of Kae1p in the KEOPS complex

Top 10 interactors (score): SUA5 (0.996); BUD32 (0.99); CGI121 (0.984); PDS5 (0.97); PCC1 (0.882); THS1 (0.857); MST1 (0.847); GON7 (0.836); KAE1 (0.826); MSW1 (0.822); TRM5 (0.796); AIM2 (0.743); AIM41 (0.742); MTG2 (0.738); MOD5 (0.734); NNR1 (0.719); YNL144C (0.706); PUF3 (0.703); DOT1 (0.691); PET309 (0.69)

Homologues (species, bitscore): OSGEPL1 (Homo sapiens, 134.0); Osgepl1 (Mus musculus, 127.5); osgepl1 (Danio rerio, 141.4); osgepl1 (Xenopus tropicalis, 124.8); CG14231 (Drosophila melanogaster, 127.9); osgl-1 (Caenorhabditis elegans, 115.2); GCP1 (Arabidopsis thaliana, 133.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:258274-259484:- gene-YDL104C_AKU4011 rna-NM_001180163.1_AKU4011 cds-NP_010179.1_AKU4011 98.1 98.9 Verified 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:290457-291680:+ gene-YDL104C_BG1 rna-NM_001180163.1_BG1 cds-NP_010179.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:275693-276910:- gene-YDL104C_Bruggeman rna-NM_001180163.1_Bruggeman cds-NP_010179.1_Bruggeman 98.8 99.5 Verified 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:272424-273647:- gene-YDL104C_CAT1 rna-NM_001180163.1_CAT1 cds-NP_010179.1_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:256538-257755:- gene-YDL104C_CBS1585 rna-NM_001180163.1_CBS1585 cds-NP_010179.1_CBS1585 98.7 99.5 Verified 1 1 0 False False False True False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:273203-274426:- gene-YDL104C_CBS436 rna-NM_001180163.1_CBS436 cds-NP_010179.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:254982-256183:- gene-YDL104C_CBS6412 rna-NM_001180163.1_CBS6412 cds-NP_010179.1_CBS6412 97.2 98.2 Mismatch 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:274585-275808:- gene-YDL104C_CBS6413 rna-NM_001180163.1_CBS6413 cds-NP_010179.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:272459-273682:- gene-YDL104C_CENPK1137D rna-NM_001180163.1_CENPK1137D cds-NP_010179.1_CENPK1137D 98.8 100.0 Verified 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:269294-270517:- gene-YDL104C_EthanolRed rna-NM_001180163.1_EthanolRed cds-NP_010179.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:275266-276489:- gene-YDL104C_FaliES1 rna-NM_001180163.1_FaliES1 cds-NP_010179.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000010.1:45316-46539:- gene-YDL104C_JAY291 rna-NM_001180163.1_JAY291 cds-NP_010179.1_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:273480-274673:- gene-YDL104C_MUCL30387 rna-NM_001180163.1_MUCL30387 cds-NP_010179.1_MUCL30387 96.8 97.5 Verified 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:264225-265448:- gene-YDL104C_MUCL30388 rna-NM_001180163.1_MUCL30388 cds-NP_010179.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:257644-258861:- gene-YDL104C_MUCL39482 rna-NM_001180163.1_MUCL39482 cds-NP_010179.1_MUCL39482 98.7 99.5 Verified 1 1 0 False False False True False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:179406-180629:- gene-YDL104C_MUCL42920 rna-NM_001180163.1_MUCL42920 cds-NP_010179.1_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:273576-274799:- gene-YDL104C_NCIM3186 rna-NM_001180163.1_NCIM3186 cds-NP_010179.1_NCIM3186 98.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:257666-258876:- gene-YDL104C_NCYC1407 rna-NM_001180163.1_NCYC1407 cds-NP_010179.1_NCYC1407 98.0 98.9 Unannotated 1 1 0 False False False True False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:264433-265656:- gene-YDL104C_PE2H3 rna-NM_001180163.1_PE2H3 cds-NP_010179.1_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:264437-265660:- gene-YDL104C_PE2H4 rna-NM_001180163.1_PE2H4 cds-NP_010179.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:273653-274876:- gene-YDL104C_S288C rna-NM_001180163.1_S288C cds-NP_010179.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000010.1:160046-161269:+ gene-YDL104C_SA1 rna-NM_001180163.1_SA1 cds-NP_010179.1_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:274777-276000:- gene-YDL104C_ThermosaccDry rna-NM_001180163.1_ThermosaccDry cds-NP_010179.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:276855-278078:- gene-YDL104C_VR1 rna-NM_001180163.1_VR1 cds-NP_010179.1_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:272702-273925:- gene-YDL104C_ZTW1 rna-NM_001180163.1_ZTW1 cds-NP_010179.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:274829-276052:- gene-YDL104C_Sparadoxus rna-NM_001180163.1_Sparadoxus cds-NP_010179.1_Sparadoxus 88.6 99.9 Verified 1 1 1 False True False False False

Additional files