Gene name: QDR3
Reference locus (S288C): YBR043C
Gene biotype: protein_coding
Description: Quinidine resistance protein 3; Multidrug transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; has a role in polyamine homeostasis; involved in spore wall asembly; sequence similarity to DTR1 and QDR1, and the triple mutant dtr1 qdr1 qdr3 exhibits reduced dityrosine fluorescence relative to the single mutants; expression is upregulated under polyamine stress; required for resistance to quinidine, barban, cisplatin, and bleomycin
Top 10 interactors (score): AZR1 (0.717); NPP1 (0.71); VBA4 (0.695); IRC18 (0.691); OSW2 (0.676); PDR12 (0.652); PDR18 (0.617); YMR279C (0.617); YER084W (0.615); SNQ2 (0.593); PDR11 (0.591); PDR10 (0.591); BSC6 (0.574); YJR124C (0.574); PDR3 (0.568); YFL040W (0.565); RRT8 (0.561); YGR017W (0.552); TPO5 (0.54); HAA1 (0.528)
Homologues (species, bitscore): B0361.11 (Caenorhabditis elegans, 50.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:304307-306376:- | gene-YBR043C_AKU4011 | rna-NM_001178391.2_AKU4011 | cds-NP_009599.2_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:294470-296539:- | gene-YBR043C_BG1 | rna-NM_001178391.2_BG1 | cds-NP_009599.2_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:305039-307108:- | gene-YBR043C_Bruggeman | rna-NM_001178391.2_Bruggeman | cds-NP_009599.2_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:308730-310799:- | gene-YBR043C_CAT1 | rna-NM_001178391.2_CAT1 | cds-NP_009599.2_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:296604-298673:- | gene-YBR043C_CBS1585 | rna-NM_001178391.2_CBS1585 | cds-NP_009599.2_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:304610-306679:- | gene-YBR043C_CBS436 | rna-NM_001178391.2_CBS436 | cds-NP_009599.2_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:394487-396556:- | gene-YBR043C_CBS6412 | rna-NM_001178391.2_CBS6412 | cds-NP_009599.2_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:301721-303790:- | gene-YBR043C_CBS6413 | rna-NM_001178391.2_CBS6413 | cds-NP_009599.2_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:315636-317705:- | gene-YBR043C_CENPK1137D | rna-NM_001178391.2_CENPK1137D | cds-NP_009599.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:431081-433150:- | gene-YBR043C_EthanolRed | rna-NM_001178391.2_EthanolRed | cds-NP_009599.2_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:319934-322003:- | gene-YBR043C_FaliES1 | rna-NM_001178391.2_FaliES1 | cds-NP_009599.2_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000441.1:9718-11787:+ | gene-YBR043C_JAY291 | rna-NM_001178391.2_JAY291 | cds-NP_009599.2_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:306667-308736:- | gene-YBR043C_MUCL30387 | rna-NM_001178391.2_MUCL30387 | cds-NP_009599.2_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:306449-308518:- | gene-YBR043C_MUCL30388 | rna-NM_001178391.2_MUCL30388 | cds-NP_009599.2_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:296592-298661:- | gene-YBR043C_MUCL39482 | rna-NM_001178391.2_MUCL39482 | cds-NP_009599.2_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:303790-305859:- | gene-YBR043C_MUCL42920 | rna-NM_001178391.2_MUCL42920 | cds-NP_009599.2_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:321673-323742:- | gene-YBR043C_NCIM3186 | rna-NM_001178391.2_NCIM3186 | cds-NP_009599.2_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:297504-299573:- | gene-YBR043C_NCYC1407 | rna-NM_001178391.2_NCYC1407 | cds-NP_009599.2_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:309676-311745:- | gene-YBR043C_PE2H3 | rna-NM_001178391.2_PE2H3 | cds-NP_009599.2_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:307352-309421:- | gene-YBR043C_PE2H4 | rna-NM_001178391.2_PE2H4 | cds-NP_009599.2_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:321876-323945:- | gene-YBR043C_S288C | rna-NM_001178391.2_S288C | cds-NP_009599.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000017.1:153598-155667:+ | gene-YBR043C_SA1 | rna-NM_001178391.2_SA1 | cds-NP_009599.2_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:319372-321441:- | gene-YBR043C_ThermosaccDry | rna-NM_001178391.2_ThermosaccDry | cds-NP_009599.2_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:301029-303098:- | gene-YBR043C_VR1 | rna-NM_001178391.2_VR1 | cds-NP_009599.2_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:295102-297171:- | gene-YBR043C_ZTW1 | rna-NM_001178391.2_ZTW1 | cds-NP_009599.2_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:331309-333378:- | gene-YBR043C_Sparadoxus | rna-NM_001178391.2_Sparadoxus | cds-NP_009599.2_Sparadoxus | 89.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |