QDR2 (YIL121W)


Gene profile

Gene name: QDR2
Reference locus (S288C): YIL121W
Gene biotype: protein_coding

Description: Quinidine resistance protein 2; Plasma membrane transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; exports copper; has broad substrate specificity and can transport many mono- and divalent cations; transports a variety of drugs and is required for resistance to quinidine, barban, cisplatin, and bleomycin; contributes to potassium homeostasis; expression is regulated by copper

Top 10 interactors (score): TPO1 (0.944); TPO2 (0.914); TPO3 (0.914); YHK8 (0.907); HOL1 (0.906); PDR12 (0.706); SNQ2 (0.703); PDR8 (0.694); YOR1 (0.694); KHA1 (0.677); PDR11 (0.667); PDR1 (0.651); AZR1 (0.622); BSC6 (0.618); TRK1 (0.61); NHA1 (0.6); ATR1 (0.574); TRK2 (0.574); PDR5 (0.572); MDR1 (0.567)

Homologues (species, bitscore): CG3168 (Drosophila melanogaster, 53.1); hmit-1.2 (Caenorhabditis elegans, 51.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:133397-135025:+ gene-YIL121W_AKU4011 rna-NM_001179469.1_AKU4011 cds-NP_012145.1_AKU4011 99.3 100.0 Verified 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000174.1:2679-4307:- gene-YIL121W_BG1 rna-NM_001179469.1_BG1 cds-NP_012145.1_BG1 99.0 100.0 Verified 1 1 0 False False False True False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:136933-138561:+ gene-YIL121W_Bruggeman rna-NM_001179469.1_Bruggeman cds-NP_012145.1_Bruggeman 99.3 100.0 Verified 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:130082-131710:+ gene-YIL121W_CAT1 rna-NM_001179469.1_CAT1 cds-NP_012145.1_CAT1 98.9 100.0 Verified 1 1 0 False False False True False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:133628-135256:+ gene-YIL121W_CBS1585 rna-NM_001179469.1_CBS1585 cds-NP_012145.1_CBS1585 99.3 100.0 Verified 1 1 0 False False False True False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:124817-126444:+ gene-YIL121W_CBS436 rna-NM_001179469.1_CBS436 cds-NP_012145.1_CBS436 99.3 99.9 Unannotated 1 1 0 False False False True False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:131107-132735:+ gene-YIL121W_CBS6412 rna-NM_001179469.1_CBS6412 cds-NP_012145.1_CBS6412 99.3 100.0 Mismatch 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:124876-126504:+ gene-YIL121W_CBS6413 rna-NM_001179469.1_CBS6413 cds-NP_012145.1_CBS6413 99.3 100.0 Verified 1 1 0 False False False True False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:123944-125572:+ gene-YIL121W_CENPK1137D rna-NM_001179469.1_CENPK1137D cds-NP_012145.1_CENPK1137D 99.4 100.0 Verified 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:118726-120354:+ gene-YIL121W_EthanolRed rna-NM_001179469.1_EthanolRed cds-NP_012145.1_EthanolRed 99.3 100.0 Verified 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:134777-136405:+ gene-YIL121W_FaliES1 rna-NM_001179469.1_FaliES1 cds-NP_012145.1_FaliES1 99.3 100.0 Verified 1 1 0 False False False True False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000383.1:12944-14572:- gene-YIL121W_JAY291 rna-NM_001179469.1_JAY291 cds-NP_012145.1_JAY291 99.0 100.0 Verified 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:134045-135673:+ gene-YIL121W_MUCL30387 rna-NM_001179469.1_MUCL30387 cds-NP_012145.1_MUCL30387 99.3 100.0 Verified 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:133627-135255:+ gene-YIL121W_MUCL30388 rna-NM_001179469.1_MUCL30388 cds-NP_012145.1_MUCL30388 99.2 100.0 Verified 1 1 0 False False False True False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:134574-136202:+ gene-YIL121W_MUCL39482 rna-NM_001179469.1_MUCL39482 cds-NP_012145.1_MUCL39482 99.3 100.0 Verified 1 1 0 False False False True False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:137814-139442:+ gene-YIL121W_MUCL42920 rna-NM_001179469.1_MUCL42920 cds-NP_012145.1_MUCL42920 99.3 100.0 Verified 1 1 0 False False False True False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:132244-133872:+ gene-YIL121W_NCIM3186 rna-NM_001179469.1_NCIM3186 cds-NP_012145.1_NCIM3186 98.9 100.0 Verified 1 1 0 False False False True False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:138560-140188:+ gene-YIL121W_NCYC1407 rna-NM_001179469.1_NCYC1407 cds-NP_012145.1_NCYC1407 99.3 100.0 Verified 1 1 0 False False False True False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:133270-134898:+ gene-YIL121W_PE2H3 rna-NM_001179469.1_PE2H3 cds-NP_012145.1_PE2H3 99.0 100.0 Verified 1 1 0 False False False True False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:127270-128898:+ gene-YIL121W_PE2H4 rna-NM_001179469.1_PE2H4 cds-NP_012145.1_PE2H4 98.9 100.0 Verified 1 1 0 False False False True False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:132244-133872:+ gene-YIL121W_S288C rna-NM_001179469.1_S288C cds-NP_012145.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000058.1:49422-51050:- gene-YIL121W_SA1 rna-NM_001179469.1_SA1 cds-NP_012145.1_SA1 99.0 100.0 Verified 1 1 0 False False False True False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:133434-135062:+ gene-YIL121W_ThermosaccDry rna-NM_001179469.1_ThermosaccDry cds-NP_012145.1_ThermosaccDry 99.3 100.0 Verified 1 1 0 False False False True False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:130579-132207:+ gene-YIL121W_VR1 rna-NM_001179469.1_VR1 cds-NP_012145.1_VR1 99.0 100.0 Verified 1 1 0 False False False True False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:108320-109948:+ gene-YIL121W_ZTW1 rna-NM_001179469.1_ZTW1 cds-NP_012145.1_ZTW1 99.3 100.0 Verified 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:126145-127773:+ gene-YIL121W_Sparadoxus rna-NM_001179469.1_Sparadoxus cds-NP_012145.1_Sparadoxus 89.6 100.0 Verified 1 1 0 False False False True False

Additional files