QDR1 (YIL120W)


Gene profile

Gene name: QDR1
Reference locus (S288C): YIL120W
Gene biotype: protein_coding

Description: Quinidine resistance protein 1; Multidrug transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; involved in spore wall assembly; sequence similarity to DTR1 and QDR3, and the triple mutant dtr1 qdr1 qdr3 exhibits reduced dityrosine fluorescence relative to the single mutants; required for resistance to quinidine, ketoconazole, fluconazole, and barban; QDR1 has a paralog, AQR1, that arose from the whole genome duplication

Top 10 interactors (score): TPO1 (0.907); HOL1 (0.906); PDR5 (0.896); IRC18 (0.749); MDR1 (0.715); SNQ2 (0.713); PDR11 (0.709); PDR3 (0.698); ATR1 (0.691); YOR1 (0.676); LOH1 (0.672); ERG11 (0.618); OSW2 (0.572); PDR1 (0.572); RRT8 (0.564); PDR12 (0.552); PDR15 (0.55); OSW7 (0.522); SEC4 (0.516); STE6 (0.502)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:135570-137261:+ gene-YIL120W_AKU4011 rna-NM_001179468.1_AKU4011 cds-NP_012146.1_AKU4011 98.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000174.1:443-2134:- gene-YIL120W_BG1 rna-NM_001179468.1_BG1 cds-NP_012146.1_BG1 98.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:139106-140797:+ gene-YIL120W_Bruggeman rna-NM_001179468.1_Bruggeman cds-NP_012146.1_Bruggeman 98.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:132254-133945:+ gene-YIL120W_CAT1 rna-NM_001179468.1_CAT1 cds-NP_012146.1_CAT1 98.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:135802-137492:+ gene-YIL120W_CBS1585 rna-NM_001179468.1_CBS1585 cds-NP_012146.1_CBS1585 98.6 99.9 Unannotated 1 1 0 False False False True False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:126988-128679:+ gene-YIL120W_CBS436 rna-NM_001179468.1_CBS436 cds-NP_012146.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:133280-134971:+ gene-YIL120W_CBS6412 rna-NM_001179468.1_CBS6412 cds-NP_012146.1_CBS6412 98.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:127047-128738:+ gene-YIL120W_CBS6413 rna-NM_001179468.1_CBS6413 cds-NP_012146.1_CBS6413 98.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:126113-127804:+ gene-YIL120W_CENPK1137D rna-NM_001179468.1_CENPK1137D cds-NP_012146.1_CENPK1137D 99.7 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:120899-122590:+ gene-YIL120W_EthanolRed rna-NM_001179468.1_EthanolRed cds-NP_012146.1_EthanolRed 98.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:136950-138641:+ gene-YIL120W_FaliES1 rna-NM_001179468.1_FaliES1 cds-NP_012146.1_FaliES1 98.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000383.1:10709-12400:- gene-YIL120W_JAY291 rna-NM_001179468.1_JAY291 cds-NP_012146.1_JAY291 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:136218-137909:+ gene-YIL120W_MUCL30387 rna-NM_001179468.1_MUCL30387 cds-NP_012146.1_MUCL30387 98.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:135800-137491:+ gene-YIL120W_MUCL30388 rna-NM_001179468.1_MUCL30388 cds-NP_012146.1_MUCL30388 98.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:136745-138435:+ gene-YIL120W_MUCL39482 rna-NM_001179468.1_MUCL39482 cds-NP_012146.1_MUCL39482 98.6 99.9 Unannotated 1 1 0 False False False True False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:139983-141674:+ gene-YIL120W_MUCL42920 rna-NM_001179468.1_MUCL42920 cds-NP_012146.1_MUCL42920 98.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:134417-136108:+ gene-YIL120W_NCIM3186 rna-NM_001179468.1_NCIM3186 cds-NP_012146.1_NCIM3186 98.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:140731-142422:+ gene-YIL120W_NCYC1407 rna-NM_001179468.1_NCYC1407 cds-NP_012146.1_NCYC1407 98.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:135442-137133:+ gene-YIL120W_PE2H3 rna-NM_001179468.1_PE2H3 cds-NP_012146.1_PE2H3 98.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:129442-131133:+ gene-YIL120W_PE2H4 rna-NM_001179468.1_PE2H4 cds-NP_012146.1_PE2H4 98.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:134417-136108:+ gene-YIL120W_S288C rna-NM_001179468.1_S288C cds-NP_012146.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000058.1:47187-48878:- gene-YIL120W_SA1 rna-NM_001179468.1_SA1 cds-NP_012146.1_SA1 99.0 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:135607-137298:+ gene-YIL120W_ThermosaccDry rna-NM_001179468.1_ThermosaccDry cds-NP_012146.1_ThermosaccDry 98.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:132751-134442:+ gene-YIL120W_VR1 rna-NM_001179468.1_VR1 cds-NP_012146.1_VR1 98.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:110493-112184:+ gene-YIL120W_ZTW1 rna-NM_001179468.1_ZTW1 cds-NP_012146.1_ZTW1 98.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:128318-130009:+ gene-YIL120W_Sparadoxus rna-NM_001179468.1_Sparadoxus cds-NP_012146.1_Sparadoxus 87.8 99.6 Verified 1 1 1 False True False False False

Additional files