Gene name: PYK2
Reference locus (S288C): YOR347C
Gene biotype: protein_coding
Description: Pyruvate kinase; appears to be modulated by phosphorylation; transcription repressed by glucose, and Pyk2p may be active under low glycolytic flux; PYK2 has a paralog, CDC19, that arose from the whole genome duplication
Top 10 interactors (score): PGI1 (0.997); MAE1 (0.997); ERR3 (0.995); ERR2 (0.995); ENO2 (0.994); ENO1 (0.994); TPI1 (0.99); ERR1 (0.985); FBA1 (0.985); GPM1 (0.979); CDC19 (0.978); PDC6 (0.976); ZWF1 (0.976); PDB1 (0.974); PYC1 (0.972); PDC1 (0.971); PGK1 (0.97); PDC5 (0.969); PDA1 (0.968); PFK1 (0.967)
Homologues (species, bitscore): PKLR (Homo sapiens, 498.4); Pklr (Mus musculus, 486.5); pkmb (Danio rerio, 471.9); pkm (Xenopus tropicalis, 489.2); PyK (Drosophila melanogaster, 478.8); pyk-2 (Caenorhabditis elegans, 478.8); AT5G08570 (Arabidopsis thaliana, 355.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:971519-973039:- | gene-YOR347C_AKU4011 | rna-NM_001183767.3_AKU4011 | cds-NP_014992.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000078.1:8630-10150:- | gene-YOR347C_BG1 | rna-NM_001183767.3_BG1 | cds-NP_014992.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:956362-957882:- | gene-YOR347C_Bruggeman | rna-NM_001183767.3_Bruggeman | cds-NP_014992.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:956176-957696:- | gene-YOR347C_CAT1 | rna-NM_001183767.3_CAT1 | cds-NP_014992.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:955931-957451:- | gene-YOR347C_CBS1585 | rna-NM_001183767.3_CBS1585 | cds-NP_014992.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:950752-952272:- | gene-YOR347C_CBS436 | rna-NM_001183767.3_CBS436 | cds-NP_014992.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:185230-186750:- | gene-YOR347C_CBS6412 | rna-NM_001183767.3_CBS6412 | cds-NP_014992.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:960201-961721:- | gene-YOR347C_CBS6413 | rna-NM_001183767.3_CBS6413 | cds-NP_014992.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:984730-986250:- | gene-YOR347C_CENPK1137D | rna-NM_001183767.3_CENPK1137D | cds-NP_014992.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:200227-201747:- | gene-YOR347C_EthanolRed | rna-NM_001183767.3_EthanolRed | cds-NP_014992.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:953056-954576:- | gene-YOR347C_FaliES1 | rna-NM_001183767.3_FaliES1 | cds-NP_014992.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000078.1:51083-52603:+ | gene-YOR347C_JAY291 | rna-NM_001183767.3_JAY291 | cds-NP_014992.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:965674-967194:- | gene-YOR347C_MUCL30387 | rna-NM_001183767.3_MUCL30387 | cds-NP_014992.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:973688-975208:- | gene-YOR347C_MUCL30388 | rna-NM_001183767.3_MUCL30388 | cds-NP_014992.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:962466-963986:- | gene-YOR347C_MUCL39482 | rna-NM_001183767.3_MUCL39482 | cds-NP_014992.3_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:970076-971596:- | gene-YOR347C_MUCL42920 | rna-NM_001183767.3_MUCL42920 | cds-NP_014992.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:984831-986351:- | gene-YOR347C_NCIM3186 | rna-NM_001183767.3_NCIM3186 | cds-NP_014992.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:963475-964995:- | gene-YOR347C_NCYC1407 | rna-NM_001183767.3_NCYC1407 | cds-NP_014992.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:958737-960257:- | gene-YOR347C_PE2H3 | rna-NM_001183767.3_PE2H3 | cds-NP_014992.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:975089-976609:- | gene-YOR347C_PE2H4 | rna-NM_001183767.3_PE2H4 | cds-NP_014992.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:984942-986462:- | gene-YOR347C_S288C | rna-NM_001183767.3_S288C | cds-NP_014992.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000016.1:89393-90913:- | gene-YOR347C_SA1 | rna-NM_001183767.3_SA1 | cds-NP_014992.3_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:952226-953746:- | gene-YOR347C_ThermosaccDry | rna-NM_001183767.3_ThermosaccDry | cds-NP_014992.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:1013100-1015011:- | gene-YOR347C_VR1 | rna-NM_001183767.3_VR1 | cds-NP_014992.3_VR1 | 79.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:684960-686480:- | gene-YOR347C_ZTW1 | rna-NM_001183767.3_ZTW1 | cds-NP_014992.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:958458-959978:- | gene-YOR347C_Sparadoxus | rna-NM_001183767.3_Sparadoxus | cds-NP_014992.3_Sparadoxus | 90.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |