Gene name: PXR1
Reference locus (S288C): YGR280C
Gene biotype: protein_coding
Description: Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in negative regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain
Top 10 interactors (score): PRP43 (0.999); EST2 (0.995); ENP1 (0.994); NOP4 (0.993); SQS1 (0.993); ROK1 (0.992); SDA1 (0.991); UTP23 (0.989); RPF1 (0.989); UTP7 (0.987); MAK16 (0.986); RRP36 (0.985); KRI1 (0.985); DHR2 (0.984); LCP5 (0.983); SSF1 (0.982); DBP10 (0.981); HCA4 (0.981); NOP7 (0.979); RRP14 (0.978)
Homologues (species, bitscore): PINX1 (Homo sapiens, 82.0); Pinx1 (Mus musculus, 80.5); pinx1 (Danio rerio, 84.0); pinx1 (Xenopus tropicalis, 83.6); CG11180 (Drosophila melanogaster, 55.1); T23G7.3 (Caenorhabditis elegans, 56.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:1016327-1017142:- | gene-YGR280C_AKU4011 | rna-NM_001181409.1_AKU4011 | cds-NP_011796.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000020.1:111-914:+ | gene-YGR280C_BG1 | rna-NM_001181409.1_BG1 | cds-NP_011796.1_BG1 | 98.1 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:1024895-1025710:- | gene-YGR280C_Bruggeman | rna-NM_001181409.1_Bruggeman | cds-NP_011796.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:1024366-1025181:- | gene-YGR280C_CAT1 | rna-NM_001181409.1_CAT1 | cds-NP_011796.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:1019195-1020010:- | gene-YGR280C_CBS1585 | rna-NM_001181409.1_CBS1585 | cds-NP_011796.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:1022872-1023687:- | gene-YGR280C_CBS436 | rna-NM_001181409.1_CBS436 | cds-NP_011796.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:1010087-1010902:- | gene-YGR280C_CBS6412 | rna-NM_001181409.1_CBS6412 | cds-NP_011796.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:1016140-1016955:- | gene-YGR280C_CBS6413 | rna-NM_001181409.1_CBS6413 | cds-NP_011796.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:1050635-1051450:- | gene-YGR280C_CENPK1137D | rna-NM_001181409.1_CENPK1137D | cds-NP_011796.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:1004177-1004980:- | gene-YGR280C_EthanolRed | rna-NM_001181409.1_EthanolRed | cds-NP_011796.1_EthanolRed | 98.5 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:1008983-1009786:- | gene-YGR280C_FaliES1 | rna-NM_001181409.1_FaliES1 | cds-NP_011796.1_FaliES1 | 98.5 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:20473-21288:+ | gene-YGR280C_JAY291 | rna-NM_001181409.1_JAY291 | cds-NP_011796.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:1022628-1023443:- | gene-YGR280C_MUCL30387 | rna-NM_001181409.1_MUCL30387 | cds-NP_011796.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:1020761-1021576:- | gene-YGR280C_MUCL30388 | rna-NM_001181409.1_MUCL30388 | cds-NP_011796.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:1014301-1015116:- | gene-YGR280C_MUCL39482 | rna-NM_001181409.1_MUCL39482 | cds-NP_011796.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:1032227-1033042:- | gene-YGR280C_MUCL42920 | rna-NM_001181409.1_MUCL42920 | cds-NP_011796.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:1050910-1051725:- | gene-YGR280C_NCIM3186 | rna-NM_001181409.1_NCIM3186 | cds-NP_011796.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:1009934-1010749:- | gene-YGR280C_NCYC1407 | rna-NM_001181409.1_NCYC1407 | cds-NP_011796.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:1035176-1035991:- | gene-YGR280C_PE2H3 | rna-NM_001181409.1_PE2H3 | cds-NP_011796.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:1040015-1040830:- | gene-YGR280C_PE2H4 | rna-NM_001181409.1_PE2H4 | cds-NP_011796.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:1050910-1051725:- | gene-YGR280C_S288C | rna-NM_001181409.1_S288C | cds-NP_011796.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000063.1:49175-49990:- | gene-YGR280C_SA1 | rna-NM_001181409.1_SA1 | cds-NP_011796.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:1029503-1030306:- | gene-YGR280C_ThermosaccDry | rna-NM_001181409.1_ThermosaccDry | cds-NP_011796.1_ThermosaccDry | 98.5 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1135352-1136167:- | gene-YGR280C_VR1 | rna-NM_001181409.1_VR1 | cds-NP_011796.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:330907-331722:- | gene-YGR280C_ZTW1 | rna-NM_001181409.1_ZTW1 | cds-NP_011796.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:1021607-1022422:- | gene-YGR280C_Sparadoxus | rna-NM_001181409.1_Sparadoxus | cds-NP_011796.1_Sparadoxus | 88.2 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |