PXP1 (YEL020C)


Gene profile

Gene name: PXP1
Reference locus (S288C): YEL020C
Gene biotype: protein_coding

Description: Putative 2-hydroxyacyl-CoA lyase; Peroxisomal matrix protein; well-conserved in fungi; contains tripartite homology domain of thiamine pyrophosphate (TPP) enzymes; targeted to peroxisomes by Pex5p; contains low sequence identity with Pdc1p; mRNA identified as translated by ribosome profiling data

Top 10 interactors (score): PCS60 (0.964); SPS19 (0.961); STE23 (0.955); POX1 (0.938); CTT1 (0.934); TES1 (0.931); CAT2 (0.924); FOX2 (0.915); FMS1 (0.915); IDP2 (0.912); PEX5 (0.905); PCD1 (0.903); NCP1 (0.901); FAT1 (0.9); DUR1,2 (0.892); YIL089W (0.844); YGR168C (0.844); YBL039W-B (0.844); PEX13 (0.831); ILV6 (0.828)

Homologues (species, bitscore): HACL1 (Homo sapiens, 381.7); Hacl1 (Mus musculus, 370.5); hacl1 (Danio rerio, 359.4); hacl1 (Xenopus tropicalis, 372.1); CG11208 (Drosophila melanogaster, 386.7); B0334.3 (Caenorhabditis elegans, 337.0); AT5G17380 (Arabidopsis thaliana, 355.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:112648-114330:- gene-YEL020C_AKU4011 rna-NM_001178835.1_AKU4011 cds-NP_010895.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:311638-313320:+ gene-YEL020C_BG1 rna-NM_001178835.1_BG1 cds-NP_010895.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:119176-120858:- gene-YEL020C_Bruggeman rna-NM_001178835.1_Bruggeman cds-NP_010895.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:114829-116511:- gene-YEL020C_CAT1 rna-NM_001178835.1_CAT1 cds-NP_010895.1_CAT1 98.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:112590-114272:- gene-YEL020C_CBS1585 rna-NM_001178835.1_CBS1585 cds-NP_010895.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:114223-115905:- gene-YEL020C_CBS436 rna-NM_001178835.1_CBS436 cds-NP_010895.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:112868-114550:- gene-YEL020C_CBS6412 rna-NM_001178835.1_CBS6412 cds-NP_010895.1_CBS6412 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:117475-119157:- gene-YEL020C_CBS6413 rna-NM_001178835.1_CBS6413 cds-NP_010895.1_CBS6413 98.9 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:116475-118157:- gene-YEL020C_CENPK1137D rna-NM_001178835.1_CENPK1137D cds-NP_010895.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:112969-114651:- gene-YEL020C_EthanolRed rna-NM_001178835.1_EthanolRed cds-NP_010895.1_EthanolRed 99.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:113228-114910:- gene-YEL020C_FaliES1 rna-NM_001178835.1_FaliES1 cds-NP_010895.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000398.1:32114-33796:- gene-YEL020C_JAY291 rna-NM_001178835.1_JAY291 cds-NP_010895.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:116896-118578:- gene-YEL020C_MUCL30387 rna-NM_001178835.1_MUCL30387 cds-NP_010895.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:112867-114549:- gene-YEL020C_MUCL30388 rna-NM_001178835.1_MUCL30388 cds-NP_010895.1_MUCL30388 99.0 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:111952-113634:- gene-YEL020C_MUCL39482 rna-NM_001178835.1_MUCL39482 cds-NP_010895.1_MUCL39482 98.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:116582-118264:- gene-YEL020C_MUCL42920 rna-NM_001178835.1_MUCL42920 cds-NP_010895.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:118616-120298:- gene-YEL020C_NCIM3186 rna-NM_001178835.1_NCIM3186 cds-NP_010895.1_NCIM3186 98.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:117057-118739:- gene-YEL020C_NCYC1407 rna-NM_001178835.1_NCYC1407 cds-NP_010895.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:121081-122763:- gene-YEL020C_PE2H3 rna-NM_001178835.1_PE2H3 cds-NP_010895.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:116996-118678:- gene-YEL020C_PE2H4 rna-NM_001178835.1_PE2H4 cds-NP_010895.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:118617-120299:- gene-YEL020C_S288C rna-NM_001178835.1_S288C cds-NP_010895.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:122921-124603:+ gene-YEL020C_SA1 rna-NM_001178835.1_SA1 cds-NP_010895.1_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:113633-115315:- gene-YEL020C_ThermosaccDry rna-NM_001178835.1_ThermosaccDry cds-NP_010895.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:113173-114855:- gene-YEL020C_VR1 rna-NM_001178835.1_VR1 cds-NP_010895.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:111995-113677:- gene-YEL020C_ZTW1 rna-NM_001178835.1_ZTW1 cds-NP_010895.1_ZTW1 99.0 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:115454-117137:- gene-YEL020C_Sparadoxus rna-NM_001178835.1_Sparadoxus cds-NP_010895.1_Sparadoxus 88.4 99.9 Mismatch 1 1 1 False True False False False

Additional files