PXL1 (YKR090W)


Gene profile

Gene name: PXL1
Reference locus (S288C): YKR090W
Gene biotype: protein_coding

Description: Paxillin-like protein 1; Protein that localizes to sites of polarized growth; required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; contains LIM domains and has similarity to metazoan paxillin; relocalizes from bud neck to cytoplasm upon DNA replication stress

Top 10 interactors (score): HOF1 (0.915); CYK3 (0.915); RHO1 (0.911); MYO1 (0.846); CDC42 (0.822); RGA2 (0.815); RGA1 (0.814); TEP1 (0.8); ACT1 (0.754); FKS1 (0.75); IQG1 (0.739); SAC6 (0.728); RHO2 (0.714); PFY1 (0.706); TPM1 (0.684); MYO2 (0.682); RGD2 (0.656); AIM44 (0.656); TPM2 (0.65); YGL242C (0.64)

Homologues (species, bitscore): LHX8 (Homo sapiens, 67.4); Lhx8 (Mus musculus, 66.6); lhx8a (Danio rerio, 63.5); lhx8 (Xenopus tropicalis, 63.9); Zasp52 (Drosophila melanogaster, 58.9); pxl-1 (Caenorhabditis elegans, 58.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:594977-597097:+ gene-YKR090W_AKU4011 rna-NM_001179880.4_AKU4011 cds-NP_013016.4_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:47128-49248:- gene-YKR090W_BG1 rna-NM_001179880.4_BG1 cds-NP_013016.4_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:617555-619675:+ gene-YKR090W_Bruggeman rna-NM_001179880.4_Bruggeman cds-NP_013016.4_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:613476-615596:+ gene-YKR090W_CAT1 rna-NM_001179880.4_CAT1 cds-NP_013016.4_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:607464-609584:+ gene-YKR090W_CBS1585 rna-NM_001179880.4_CBS1585 cds-NP_013016.4_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:605849-607969:+ gene-YKR090W_CBS436 rna-NM_001179880.4_CBS436 cds-NP_013016.4_CBS436 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:590752-592872:+ gene-YKR090W_CBS6412 rna-NM_001179880.4_CBS6412 cds-NP_013016.4_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:607282-609402:+ gene-YKR090W_CBS6413 rna-NM_001179880.4_CBS6413 cds-NP_013016.4_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:608601-610721:+ gene-YKR090W_CENPK1137D rna-NM_001179880.4_CENPK1137D cds-NP_013016.4_CENPK1137D 99.2 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:604788-606908:+ gene-YKR090W_EthanolRed rna-NM_001179880.4_EthanolRed cds-NP_013016.4_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:608683-610803:+ gene-YKR090W_FaliES1 rna-NM_001179880.4_FaliES1 cds-NP_013016.4_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000426.1:34130-36250:- gene-YKR090W_JAY291 rna-NM_001179880.4_JAY291 cds-NP_013016.4_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:617050-619170:+ gene-YKR090W_MUCL30387 rna-NM_001179880.4_MUCL30387 cds-NP_013016.4_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:611394-613514:+ gene-YKR090W_MUCL30388 rna-NM_001179880.4_MUCL30388 cds-NP_013016.4_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:606305-608425:+ gene-YKR090W_MUCL39482 rna-NM_001179880.4_MUCL39482 cds-NP_013016.4_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:612328-614448:+ gene-YKR090W_MUCL42920 rna-NM_001179880.4_MUCL42920 cds-NP_013016.4_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:608935-611055:+ gene-YKR090W_NCIM3186 rna-NM_001179880.4_NCIM3186 cds-NP_013016.4_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:606717-608837:+ gene-YKR090W_NCYC1407 rna-NM_001179880.4_NCYC1407 cds-NP_013016.4_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:631922-634042:+ gene-YKR090W_PE2H3 rna-NM_001179880.4_PE2H3 cds-NP_013016.4_PE2H3 99.1 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:616326-618446:+ gene-YKR090W_PE2H4 rna-NM_001179880.4_PE2H4 cds-NP_013016.4_PE2H4 99.1 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:608946-611066:+ gene-YKR090W_S288C rna-NM_001179880.4_S288C cds-NP_013016.4_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000029.1:70783-72903:- gene-YKR090W_SA1 rna-NM_001179880.4_SA1 cds-NP_013016.4_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:607930-610050:+ gene-YKR090W_ThermosaccDry rna-NM_001179880.4_ThermosaccDry cds-NP_013016.4_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:607193-609313:+ gene-YKR090W_VR1 rna-NM_001179880.4_VR1 cds-NP_013016.4_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:604911-607031:+ gene-YKR090W_ZTW1 rna-NM_001179880.4_ZTW1 cds-NP_013016.4_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:630213-632348:+ gene-YKR090W_Sparadoxus rna-NM_001179880.4_Sparadoxus cds-NP_013016.4_Sparadoxus 86.8 99.8 Verified 1 1 1 False True False False False

Additional files