Gene name: PXA2
Reference locus (S288C): YKL188C
Gene biotype: protein_coding
Description: Peroxisomal long-chain fatty acid import protein 1; Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p; required for import of long-chain fatty acids into peroxisomes; similar to human adrenoleukodystrophy transportesr ABCD1 and ABCD2, and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; human ABCD1 and ABCD2 can each partially complement yeast pxa1 pxa2 double null mutant; Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily
Top 10 interactors (score): PXA1 (0.994); PEX11 (0.987); FAA2 (0.975); PEX13 (0.971); FOX2 (0.962); PEX12 (0.959); PEX14 (0.954); POX1 (0.937); HFD1 (0.928); MSP1 (0.912); FIS1 (0.909); SYM1 (0.906); PEX19 (0.902); PEX3 (0.885); ECI1 (0.837); CTA1 (0.8); PEX5 (0.785); TES1 (0.774); LSM6 (0.772); DCI1 (0.762)
Homologues (species, bitscore): ABCD2 (Homo sapiens, 347.4); Abcd2 (Mus musculus, 352.4); abcd1 (Danio rerio, 328.2); abcd1 (Xenopus tropicalis, 328.6); CG2316 (Drosophila melanogaster, 323.6); pmp-4 (Caenorhabditis elegans, 327.4); ABCD1 (Arabidopsis thaliana, 239.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:73075-75636:- | gene-YKL188C_AKU4011 | rna-NM_001179754.1_AKU4011 | cds-NP_012733.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:49601-52162:- | gene-YKL188C_BG1 | rna-NM_001179754.1_BG1 | cds-NP_012733.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:90460-93021:- | gene-YKL188C_Bruggeman | rna-NM_001179754.1_Bruggeman | cds-NP_012733.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:85420-87981:- | gene-YKL188C_CAT1 | rna-NM_001179754.1_CAT1 | cds-NP_012733.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:85057-87618:- | gene-YKL188C_CBS1585 | rna-NM_001179754.1_CBS1585 | cds-NP_012733.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:83814-86375:- | gene-YKL188C_CBS436 | rna-NM_001179754.1_CBS436 | cds-NP_012733.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:70648-73209:- | gene-YKL188C_CBS6412 | rna-NM_001179754.1_CBS6412 | cds-NP_012733.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:85776-88337:- | gene-YKL188C_CBS6413 | rna-NM_001179754.1_CBS6413 | cds-NP_012733.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:86052-88613:- | gene-YKL188C_CENPK1137D | rna-NM_001179754.1_CENPK1137D | cds-NP_012733.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:83962-86523:- | gene-YKL188C_EthanolRed | rna-NM_001179754.1_EthanolRed | cds-NP_012733.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:84663-87224:- | gene-YKL188C_FaliES1 | rna-NM_001179754.1_FaliES1 | cds-NP_012733.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000006.2:83646-86206:- | gene-YKL188C_JAY291 | rna-NM_001179754.1_JAY291 | cds-NP_012733.1_JAY291 | 99.6 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:92761-95322:- | gene-YKL188C_MUCL30387 | rna-NM_001179754.1_MUCL30387 | cds-NP_012733.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:87105-89666:- | gene-YKL188C_MUCL30388 | rna-NM_001179754.1_MUCL30388 | cds-NP_012733.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:85114-87675:- | gene-YKL188C_MUCL39482 | rna-NM_001179754.1_MUCL39482 | cds-NP_012733.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:89447-92008:- | gene-YKL188C_MUCL42920 | rna-NM_001179754.1_MUCL42920 | cds-NP_012733.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:86214-88775:- | gene-YKL188C_NCIM3186 | rna-NM_001179754.1_NCIM3186 | cds-NP_012733.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:85138-87699:- | gene-YKL188C_NCYC1407 | rna-NM_001179754.1_NCYC1407 | cds-NP_012733.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:92188-94749:- | gene-YKL188C_PE2H3 | rna-NM_001179754.1_PE2H3 | cds-NP_012733.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:88482-91043:- | gene-YKL188C_PE2H4 | rna-NM_001179754.1_PE2H4 | cds-NP_012733.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:86225-88786:- | gene-YKL188C_S288C | rna-NM_001179754.1_S288C | cds-NP_012733.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:2426-4987:- | gene-YKL188C_SA1 | rna-NM_001179754.1_SA1 | cds-NP_012733.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:85363-87924:- | gene-YKL188C_ThermosaccDry | rna-NM_001179754.1_ThermosaccDry | cds-NP_012733.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:83893-86454:- | gene-YKL188C_VR1 | rna-NM_001179754.1_VR1 | cds-NP_012733.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:83766-86327:- | gene-YKL188C_ZTW1 | rna-NM_001179754.1_ZTW1 | cds-NP_012733.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:98348-100909:- | gene-YKL188C_Sparadoxus | rna-NM_001179754.1_Sparadoxus | cds-NP_012733.1_Sparadoxus | 89.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |