Gene name: PXA1
Reference locus (S288C): YPL147W
Gene biotype: protein_coding
Description: Peroxisomal long-chain fatty acid import protein 2; Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p; required for import of long-chain fatty acids into peroxisomes; similar to human adrenoleukodystrophy transporters ABCD1and ABCD2, and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; human ABCD1 and ABCD2 can each partially complement yeast pxa1 pxa2 double null mutant; Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily
Top 10 interactors (score): PEX11 (0.997); PEX13 (0.995); PXA2 (0.994); FOX2 (0.994); FAA2 (0.983); PEX12 (0.974); PEX14 (0.969); POX1 (0.952); HFD1 (0.931); PEX3 (0.915); PEX19 (0.915); FIS1 (0.911); MSP1 (0.91); SYM1 (0.906); PEX5 (0.891); CAT2 (0.877); ADH4 (0.875); ECI1 (0.863); CTA1 (0.857); OSM1 (0.847)
Homologues (species, bitscore): ABCD2 (Homo sapiens, 390.2); Abcd2 (Mus musculus, 382.5); abcd1 (Danio rerio, 394.8); abcd1 (Xenopus tropicalis, 383.3); CG2316 (Drosophila melanogaster, 337.0); pmp-4 (Caenorhabditis elegans, 337.8); ABCD1 (Arabidopsis thaliana, 246.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:250910-253522:+ | gene-YPL147W_AKU4011 | rna-NM_001183961.1_AKU4011 | cds-NP_015178.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:456598-459210:+ | gene-YPL147W_BG1 | rna-NM_001183961.1_BG1 | cds-NP_015178.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:276903-279515:+ | gene-YPL147W_Bruggeman | rna-NM_001183961.1_Bruggeman | cds-NP_015178.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:273587-276199:+ | gene-YPL147W_CAT1 | rna-NM_001183961.1_CAT1 | cds-NP_015178.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:254973-257585:+ | gene-YPL147W_CBS1585 | rna-NM_001183961.1_CBS1585 | cds-NP_015178.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:269650-272262:+ | gene-YPL147W_CBS436 | rna-NM_001183961.1_CBS436 | cds-NP_015178.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:259651-262263:+ | gene-YPL147W_CBS6412 | rna-NM_001183961.1_CBS6412 | cds-NP_015178.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:251613-254225:+ | gene-YPL147W_CBS6413 | rna-NM_001183961.1_CBS6413 | cds-NP_015178.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:273157-275769:+ | gene-YPL147W_CENPK1137D | rna-NM_001183961.1_CENPK1137D | cds-NP_015178.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:249600-252212:+ | gene-YPL147W_EthanolRed | rna-NM_001183961.1_EthanolRed | cds-NP_015178.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:257192-259804:+ | gene-YPL147W_FaliES1 | rna-NM_001183961.1_FaliES1 | cds-NP_015178.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000007.1:106047-108658:- | gene-YPL147W_JAY291 | rna-NM_001183961.1_JAY291 | cds-NP_015178.1_JAY291 | 99.5 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:268146-270758:+ | gene-YPL147W_MUCL30387 | rna-NM_001183961.1_MUCL30387 | cds-NP_015178.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:266163-268775:+ | gene-YPL147W_MUCL30388 | rna-NM_001183961.1_MUCL30388 | cds-NP_015178.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:248302-250914:+ | gene-YPL147W_MUCL39482 | rna-NM_001183961.1_MUCL39482 | cds-NP_015178.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:305543-308155:+ | gene-YPL147W_MUCL42920 | rna-NM_001183961.1_MUCL42920 | cds-NP_015178.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:273238-275850:+ | gene-YPL147W_NCIM3186 | rna-NM_001183961.1_NCIM3186 | cds-NP_015178.1_NCIM3186 | 95.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:254765-257377:+ | gene-YPL147W_NCYC1407 | rna-NM_001183961.1_NCYC1407 | cds-NP_015178.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:262212-264824:+ | gene-YPL147W_PE2H3 | rna-NM_001183961.1_PE2H3 | cds-NP_015178.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:261843-264455:+ | gene-YPL147W_PE2H4 | rna-NM_001183961.1_PE2H4 | cds-NP_015178.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:273255-275867:+ | gene-YPL147W_S288C | rna-NM_001183961.1_S288C | cds-NP_015178.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000012.1:97820-100432:- | gene-YPL147W_SA1 | rna-NM_001183961.1_SA1 | cds-NP_015178.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:256990-259602:+ | gene-YPL147W_ThermosaccDry | rna-NM_001183961.1_ThermosaccDry | cds-NP_015178.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:271971-274583:+ | gene-YPL147W_VR1 | rna-NM_001183961.1_VR1 | cds-NP_015178.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:256318-258930:+ | gene-YPL147W_ZTW1 | rna-NM_001183961.1_ZTW1 | cds-NP_015178.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:257992-260604:+ | gene-YPL147W_Sparadoxus | rna-NM_001183961.1_Sparadoxus | cds-NP_015178.1_Sparadoxus | 90.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |