PWP2 (YCR057C)


Gene profile

Gene name: PWP2
Reference locus (S288C): YCR057C
Gene biotype: protein_coding

Description: Periodic tryptophan protein 2; Conserved 90S pre-ribosomal component; essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis

Top 10 interactors (score): MPP10 (0.999); KRE33 (0.999); SOF1 (0.999); NOC4 (0.999); UTP14 (0.999); NOP14 (0.999); UTP9 (0.999); HCA4 (0.999); UTP10 (0.999); UTP7 (0.999); ECM16 (0.999); UTP22 (0.999); EMG1 (0.999); MAK21 (0.999); NOP9 (0.999); UTP21 (0.999); BUD21 (0.999); RRP7 (0.999); KRR1 (0.999); UTP20 (0.999)

Homologues (species, bitscore): PWP2 (Homo sapiens, 768.1); Pwp2 (Mus musculus, 775.0); pwp2h (Danio rerio, 736.9); pwp2 (Xenopus tropicalis, 251.5); CG12325 (Drosophila melanogaster, 684.9); F55F8.3 (Caenorhabditis elegans, 554.7); PWP2 (Arabidopsis thaliana, 691.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:214917-217688:- gene-YCR057C_AKU4011 rna-NM_001178769.1_AKU4011 cds-NP_009984.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000067.1:69118-71889:- gene-YCR057C_BG1 rna-NM_001178769.1_BG1 cds-NP_009984.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:210875-213646:- gene-YCR057C_Bruggeman rna-NM_001178769.1_Bruggeman cds-NP_009984.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:222248-225019:- gene-YCR057C_CAT1 rna-NM_001178769.1_CAT1 cds-NP_009984.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:209695-212466:- gene-YCR057C_CBS1585 rna-NM_001178769.1_CBS1585 cds-NP_009984.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:221590-224361:- gene-YCR057C_CBS436 rna-NM_001178769.1_CBS436 cds-NP_009984.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:201435-204206:- gene-YCR057C_CBS6412 rna-NM_001178769.1_CBS6412 cds-NP_009984.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:215812-218583:- gene-YCR057C_CBS6413 rna-NM_001178769.1_CBS6413 cds-NP_009984.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:219641-222412:- gene-YCR057C_CENPK1137D rna-NM_001178769.1_CENPK1137D cds-NP_009984.1_CENPK1137D 99.5 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:210880-213651:- gene-YCR057C_EthanolRed rna-NM_001178769.1_EthanolRed cds-NP_009984.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:216045-218816:- gene-YCR057C_FaliES1 rna-NM_001178769.1_FaliES1 cds-NP_009984.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000014.1:4366-7137:+ gene-YCR057C_JAY291 rna-NM_001178769.1_JAY291 cds-NP_009984.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:207859-210630:- gene-YCR057C_MUCL30387 rna-NM_001178769.1_MUCL30387 cds-NP_009984.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:207233-210004:- gene-YCR057C_MUCL30388 rna-NM_001178769.1_MUCL30388 cds-NP_009984.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:216268-219039:- gene-YCR057C_MUCL39482 rna-NM_001178769.1_MUCL39482 cds-NP_009984.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:212709-215480:- gene-YCR057C_MUCL42920 rna-NM_001178769.1_MUCL42920 cds-NP_009984.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:220089-222860:- gene-YCR057C_NCIM3186 rna-NM_001178769.1_NCIM3186 cds-NP_009984.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:217127-219898:- gene-YCR057C_NCYC1407 rna-NM_001178769.1_NCYC1407 cds-NP_009984.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:225803-228574:- gene-YCR057C_PE2H3 rna-NM_001178769.1_PE2H3 cds-NP_009984.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:220329-223100:- gene-YCR057C_PE2H4 rna-NM_001178769.1_PE2H4 cds-NP_009984.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:220457-223228:- gene-YCR057C_S288C rna-NM_001178769.1_S288C cds-NP_009984.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000044.1:20343-23114:- gene-YCR057C_SA1 rna-NM_001178769.1_SA1 cds-NP_009984.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:216028-218799:- gene-YCR057C_ThermosaccDry rna-NM_001178769.1_ThermosaccDry cds-NP_009984.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:227301-230072:- gene-YCR057C_VR1 rna-NM_001178769.1_VR1 cds-NP_009984.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:213850-216621:- gene-YCR057C_ZTW1 rna-NM_001178769.1_ZTW1 cds-NP_009984.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:248007-250769:- gene-YCR057C_Sparadoxus rna-NM_001178769.1_Sparadoxus cds-NP_009984.1_Sparadoxus 91.8 99.6 Verified 1 1 1 False True False False False

Additional files