Gene name: PUT2
Reference locus (S288C): YHR037W
Gene biotype: protein_coding
Description: Delta-1-pyrroline-5-carboxylate dehydrogenase; nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of human homolog ALDH4A1 causes type II hyperprolinemia (HPII), an autosomal recessive inborn error of metabolism; human homolog ALDH4A1 can complement yeast null mutant
Top 10 interactors (score): PUT1 (0.999); PRO2 (0.994); CAR2 (0.991); PRO3 (0.991); PRO1 (0.989); GDH2 (0.986); GDH3 (0.977); GLN1 (0.973); GDH1 (0.971); YHR033W (0.958); AAT2 (0.952); PUT3 (0.943); GAD1 (0.941); GLT1 (0.932); AAT1 (0.927); CAR1 (0.907); GCV2 (0.905); FMP32 (0.889); PUT4 (0.882); GCV1 (0.862)
Homologues (species, bitscore): ALDH4A1 (Homo sapiens, 444.1); Aldh4a1 (Mus musculus, 443.7); aldh4a1 (Danio rerio, 454.9); aldh4a1 (Xenopus tropicalis, 313.9); P5CDh1 (Drosophila melanogaster, 434.9); alh-6 (Caenorhabditis elegans, 415.2); ALDH2B7 (Arabidopsis thaliana, 153.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:170247-171974:+ | gene-YHR037W_AKU4011 | rna-NM_001179167.1_AKU4011 | cds-NP_011902.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:90452-92179:+ | gene-YHR037W_BG1 | rna-NM_001179167.1_BG1 | cds-NP_011902.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:177686-179413:+ | gene-YHR037W_Bruggeman | rna-NM_001179167.1_Bruggeman | cds-NP_011902.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:172071-173798:+ | gene-YHR037W_CAT1 | rna-NM_001179167.1_CAT1 | cds-NP_011902.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:170619-172346:+ | gene-YHR037W_CBS1585 | rna-NM_001179167.1_CBS1585 | cds-NP_011902.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:164854-166581:+ | gene-YHR037W_CBS436 | rna-NM_001179167.1_CBS436 | cds-NP_011902.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:169581-171308:+ | gene-YHR037W_CBS6412 | rna-NM_001179167.1_CBS6412 | cds-NP_011902.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:170426-172153:+ | gene-YHR037W_CBS6413 | rna-NM_001179167.1_CBS6413 | cds-NP_011902.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:175238-176965:+ | gene-YHR037W_CENPK1137D | rna-NM_001179167.1_CENPK1137D | cds-NP_011902.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:169751-171478:+ | gene-YHR037W_EthanolRed | rna-NM_001179167.1_EthanolRed | cds-NP_011902.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:170730-172457:+ | gene-YHR037W_FaliES1 | rna-NM_001179167.1_FaliES1 | cds-NP_011902.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000273.1:9191-10918:- | gene-YHR037W_JAY291 | rna-NM_001179167.1_JAY291 | cds-NP_011902.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:176755-178482:+ | gene-YHR037W_MUCL30387 | rna-NM_001179167.1_MUCL30387 | cds-NP_011902.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:177225-178952:+ | gene-YHR037W_MUCL30388 | rna-NM_001179167.1_MUCL30388 | cds-NP_011902.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:169656-171383:+ | gene-YHR037W_MUCL39482 | rna-NM_001179167.1_MUCL39482 | cds-NP_011902.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:176315-178042:+ | gene-YHR037W_MUCL42920 | rna-NM_001179167.1_MUCL42920 | cds-NP_011902.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:181859-183586:+ | gene-YHR037W_NCIM3186 | rna-NM_001179167.1_NCIM3186 | cds-NP_011902.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:169519-171246:+ | gene-YHR037W_NCYC1407 | rna-NM_001179167.1_NCYC1407 | cds-NP_011902.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:171849-173576:+ | gene-YHR037W_PE2H3 | rna-NM_001179167.1_PE2H3 | cds-NP_011902.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:179290-181017:+ | gene-YHR037W_PE2H4 | rna-NM_001179167.1_PE2H4 | cds-NP_011902.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:181977-183704:+ | gene-YHR037W_S288C | rna-NM_001179167.1_S288C | cds-NP_011902.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000014.1:174866-176593:- | gene-YHR037W_SA1 | rna-NM_001179167.1_SA1 | cds-NP_011902.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:171819-173546:+ | gene-YHR037W_ThermosaccDry | rna-NM_001179167.1_ThermosaccDry | cds-NP_011902.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:178340-180067:+ | gene-YHR037W_VR1 | rna-NM_001179167.1_VR1 | cds-NP_011902.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:163370-165097:+ | gene-YHR037W_ZTW1 | rna-NM_001179167.1_ZTW1 | cds-NP_011902.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:169441-171168:+ | gene-YHR037W_Sparadoxus | rna-NM_001179167.1_Sparadoxus | cds-NP_011902.1_Sparadoxus | 90.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |