PUS7 (YOR243C)


Gene profile

Gene name: PUS7
Reference locus (S288C): YOR243C
Gene biotype: protein_coding

Description: Pseudouridine synthase; catalyzes pseudouridylation at positions 35 and 56 in U2 snRNA, position 50 in 5S rRNA, position 13 in cytoplasmic tRNAs, and position 35 in pre-tRNA(Tyr); also pseudouridylates some mRNAs; relocates from nucleus to cytoplasm during heat shock and differentially modifies some mRNAs during heat shock; conserved in archaea, vertebrates, and some bacteria; Belongs to the pseudouridine synthase TruD family

Top 10 interactors (score): PUS4 (0.993); PUS1 (0.986); PUS9 (0.982); NCL1 (0.979); CBF5 (0.979); DEG1 (0.976); TRM7 (0.974); PUS6 (0.974); BRX1 (0.967); PUS5 (0.967); PUS2 (0.965); RIB2 (0.963); NOP4 (0.959); NHP2 (0.953); YTM1 (0.949); NOP2 (0.948); UTP21 (0.946); NOC3 (0.944); NOC2 (0.943); UTP5 (0.941)

Homologues (species, bitscore): PUS7 (Homo sapiens, 361.3); Pus7 (Mus musculus, 359.8); pus7 (Danio rerio, 364.0); pus7 (Xenopus tropicalis, 377.5); CG6745 (Drosophila melanogaster, 303.5); B0024.11 (Caenorhabditis elegans, 166.0); AT3G04820 (Arabidopsis thaliana, 347.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:780983-783013:- gene-YOR243C_AKU4011 rna-NM_001183662.1_AKU4011 cds-NP_014886.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:183023-185053:- gene-YOR243C_BG1 rna-NM_001183662.1_BG1 cds-NP_014886.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:766450-768480:- gene-YOR243C_Bruggeman rna-NM_001183662.1_Bruggeman cds-NP_014886.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:767101-769131:- gene-YOR243C_CAT1 rna-NM_001183662.1_CAT1 cds-NP_014886.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:763972-766002:- gene-YOR243C_CBS1585 rna-NM_001183662.1_CBS1585 cds-NP_014886.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:762667-764697:- gene-YOR243C_CBS436 rna-NM_001183662.1_CBS436 cds-NP_014886.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:761091-763121:- gene-YOR243C_CBS6412 rna-NM_001183662.1_CBS6412 cds-NP_014886.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:769731-771761:- gene-YOR243C_CBS6413 rna-NM_001183662.1_CBS6413 cds-NP_014886.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:789974-792004:- gene-YOR243C_CENPK1137D rna-NM_001183662.1_CENPK1137D cds-NP_014886.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:757103-759133:- gene-YOR243C_EthanolRed rna-NM_001183662.1_EthanolRed cds-NP_014886.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:762502-764532:- gene-YOR243C_FaliES1 rna-NM_001183662.1_FaliES1 cds-NP_014886.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000381.1:62305-64335:+ gene-YOR243C_JAY291 rna-NM_001183662.1_JAY291 cds-NP_014886.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:770721-772751:- gene-YOR243C_MUCL30387 rna-NM_001183662.1_MUCL30387 cds-NP_014886.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:777839-779869:- gene-YOR243C_MUCL30388 rna-NM_001183662.1_MUCL30388 cds-NP_014886.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:771302-773332:- gene-YOR243C_MUCL39482 rna-NM_001183662.1_MUCL39482 cds-NP_014886.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:780891-782921:- gene-YOR243C_MUCL42920 rna-NM_001183662.1_MUCL42920 cds-NP_014886.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:790100-792130:- gene-YOR243C_NCIM3186 rna-NM_001183662.1_NCIM3186 cds-NP_014886.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:771401-773431:- gene-YOR243C_NCYC1407 rna-NM_001183662.1_NCYC1407 cds-NP_014886.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:770703-772733:- gene-YOR243C_PE2H3 rna-NM_001183662.1_PE2H3 cds-NP_014886.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:781080-783110:- gene-YOR243C_PE2H4 rna-NM_001183662.1_PE2H4 cds-NP_014886.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:790211-792241:- gene-YOR243C_S288C rna-NM_001183662.1_S288C cds-NP_014886.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:200204-202234:- gene-YOR243C_SA1 rna-NM_001183662.1_SA1 cds-NP_014886.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:761685-763715:- gene-YOR243C_ThermosaccDry rna-NM_001183662.1_ThermosaccDry cds-NP_014886.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:825143-827173:- gene-YOR243C_VR1 rna-NM_001183662.1_VR1 cds-NP_014886.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:494601-496631:- gene-YOR243C_ZTW1 rna-NM_001183662.1_ZTW1 cds-NP_014886.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:767590-769620:- gene-YOR243C_Sparadoxus rna-NM_001183662.1_Sparadoxus cds-NP_014886.1_Sparadoxus 90.7 99.8 Verified 1 1 1 False True False False False

Additional files