Gene name: PUS6
Reference locus (S288C): YGR169C
Gene biotype: protein_coding
Description: tRNA:pseudouridine synthase; catalyzes the conversion of uridine to pseudouridine at position 31 in cytoplasmic and mitochondrial tRNAs; mutation of Asp168 to Ala abolishes enzyme activity; not essential for viability
Top 10 interactors (score): PUS7 (0.974); PUS2 (0.966); PUS1 (0.945); PUS4 (0.944); PUS5 (0.944); DEG1 (0.898); CBF5 (0.665); NHP2 (0.59); NOP10 (0.588); TBS1 (0.568); RPL11A (0.567); MSS1 (0.536); GAR1 (0.505); DED81 (0.499); YLL054C (0.497); TRM3 (0.47); IFM1 (0.457); MRM1 (0.434); MTG2 (0.434); DIM1 (0.432)
Homologues (species, bitscore): RPUSD2 (Homo sapiens, 193.4); Rpusd2 (Mus musculus, 193.4); LOC565088 (Danio rerio, 178.3); rpusd2 (Xenopus tropicalis, 195.3); RluA-2 (Drosophila melanogaster, 170.6); K07E8.7 (Caenorhabditis elegans, 136.7); AT5G51140 (Arabidopsis thaliana, 167.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:802445-803659:- | gene-YGR169C_AKU4011 | rna-NM_001181298.3_AKU4011 | cds-NP_011685.3_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:80568-81782:- | gene-YGR169C_BG1 | rna-NM_001181298.3_BG1 | cds-NP_011685.3_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:808376-809590:- | gene-YGR169C_Bruggeman | rna-NM_001181298.3_Bruggeman | cds-NP_011685.3_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:804227-805441:- | gene-YGR169C_CAT1 | rna-NM_001181298.3_CAT1 | cds-NP_011685.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:803161-804375:- | gene-YGR169C_CBS1585 | rna-NM_001181298.3_CBS1585 | cds-NP_011685.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:807051-808265:- | gene-YGR169C_CBS436 | rna-NM_001181298.3_CBS436 | cds-NP_011685.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:794530-795744:- | gene-YGR169C_CBS6412 | rna-NM_001181298.3_CBS6412 | cds-NP_011685.3_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:800025-801239:- | gene-YGR169C_CBS6413 | rna-NM_001181298.3_CBS6413 | cds-NP_011685.3_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:834424-835638:- | gene-YGR169C_CENPK1137D | rna-NM_001181298.3_CENPK1137D | cds-NP_011685.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:789035-790249:- | gene-YGR169C_EthanolRed | rna-NM_001181298.3_EthanolRed | cds-NP_011685.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:793426-794640:- | gene-YGR169C_FaliES1 | rna-NM_001181298.3_FaliES1 | cds-NP_011685.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000112.1:35343-36557:- | gene-YGR169C_JAY291 | rna-NM_001181298.3_JAY291 | cds-NP_011685.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:805866-807080:- | gene-YGR169C_MUCL30387 | rna-NM_001181298.3_MUCL30387 | cds-NP_011685.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:805565-806779:- | gene-YGR169C_MUCL30388 | rna-NM_001181298.3_MUCL30388 | cds-NP_011685.3_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:798736-799950:- | gene-YGR169C_MUCL39482 | rna-NM_001181298.3_MUCL39482 | cds-NP_011685.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:813689-814903:- | gene-YGR169C_MUCL42920 | rna-NM_001181298.3_MUCL42920 | cds-NP_011685.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:834689-835903:- | gene-YGR169C_NCIM3186 | rna-NM_001181298.3_NCIM3186 | cds-NP_011685.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:793844-795058:- | gene-YGR169C_NCYC1407 | rna-NM_001181298.3_NCYC1407 | cds-NP_011685.3_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:813037-814251:- | gene-YGR169C_PE2H3 | rna-NM_001181298.3_PE2H3 | cds-NP_011685.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:818147-819361:- | gene-YGR169C_PE2H4 | rna-NM_001181298.3_PE2H4 | cds-NP_011685.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:834689-835903:- | gene-YGR169C_S288C | rna-NM_001181298.3_S288C | cds-NP_011685.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000035.1:58345-59559:- | gene-YGR169C_SA1 | rna-NM_001181298.3_SA1 | cds-NP_011685.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:813937-815151:- | gene-YGR169C_ThermosaccDry | rna-NM_001181298.3_ThermosaccDry | cds-NP_011685.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:918187-919401:- | gene-YGR169C_VR1 | rna-NM_001181298.3_VR1 | cds-NP_011685.3_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:115381-116595:- | gene-YGR169C_ZTW1 | rna-NM_001181298.3_ZTW1 | cds-NP_011685.3_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:804829-806043:- | gene-YGR169C_Sparadoxus | rna-NM_001181298.3_Sparadoxus | cds-NP_011685.3_Sparadoxus | 90.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |