Gene name: PUS2
Reference locus (S288C): YGL063W
Gene biotype: protein_coding
Description: Mitochondrial tRNA:pseudouridine synthase; acts at positions 27 and 28, but not at position 72; efficiently and rapidly targeted to mitochondria, specifically dedicated to mitochondrial tRNA modification; mutation also affects pseudouridylation of some nuclear-encoded mRNAs; PUS2 has a paralog, PUS1, that arose from the whole genome duplication
Top 10 interactors (score): PUS4 (0.978); PUS5 (0.969); PUS6 (0.966); PUS7 (0.965); DEG1 (0.964); PUS9 (0.964); RIB2 (0.941); MRM2 (0.86); CBF5 (0.858); TRP5 (0.781); PUS1 (0.775); YMR147W (0.75); YFL064C (0.75); NCL1 (0.733); TRM1 (0.719); TRP3 (0.716); YBL111C (0.711); YRF1-8 (0.71); TRM7 (0.707); TRM82 (0.705)
Homologues (species, bitscore): PUS1 (Homo sapiens, 150.6); Pus1 (Mus musculus, 136.3); pus1 (Danio rerio, 155.2); pus1 (Xenopus tropicalis, 151.4); CG4159 (Drosophila melanogaster, 144.8); pus-1 (Caenorhabditis elegans, 120.9); AT1G20370 (Arabidopsis thaliana, 159.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:386647-387759:+ | gene-YGL063W_AKU4011 | rna-NM_001180928.4_AKU4011 | cds-NP_011452.4_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:17634-18746:- | gene-YGL063W_BG1 | rna-NM_001180928.4_BG1 | cds-NP_011452.4_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:389124-390236:+ | gene-YGL063W_Bruggeman | rna-NM_001180928.4_Bruggeman | cds-NP_011452.4_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:386119-387231:+ | gene-YGL063W_CAT1 | rna-NM_001180928.4_CAT1 | cds-NP_011452.4_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:390192-391304:+ | gene-YGL063W_CBS1585 | rna-NM_001180928.4_CBS1585 | cds-NP_011452.4_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:384329-385441:+ | gene-YGL063W_CBS436 | rna-NM_001180928.4_CBS436 | cds-NP_011452.4_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:374351-375463:+ | gene-YGL063W_CBS6412 | rna-NM_001180928.4_CBS6412 | cds-NP_011452.4_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:384277-385389:+ | gene-YGL063W_CBS6413 | rna-NM_001180928.4_CBS6413 | cds-NP_011452.4_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:383841-384953:+ | gene-YGL063W_CENPK1137D | rna-NM_001180928.4_CENPK1137D | cds-NP_011452.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:375717-376829:+ | gene-YGL063W_EthanolRed | rna-NM_001180928.4_EthanolRed | cds-NP_011452.4_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:378279-379391:+ | gene-YGL063W_FaliES1 | rna-NM_001180928.4_FaliES1 | cds-NP_011452.4_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000369.1:63986-65098:+ | gene-YGL063W_JAY291 | rna-NM_001180928.4_JAY291 | cds-NP_011452.4_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:386320-387432:+ | gene-YGL063W_MUCL30387 | rna-NM_001180928.4_MUCL30387 | cds-NP_011452.4_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:389367-390479:+ | gene-YGL063W_MUCL30388 | rna-NM_001180928.4_MUCL30388 | cds-NP_011452.4_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:386500-387612:+ | gene-YGL063W_MUCL39482 | rna-NM_001180928.4_MUCL39482 | cds-NP_011452.4_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:186497-187609:- | gene-YGL063W_MUCL42920 | rna-NM_001180928.4_MUCL42920 | cds-NP_011452.4_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:383654-384766:+ | gene-YGL063W_NCIM3186 | rna-NM_001180928.4_NCIM3186 | cds-NP_011452.4_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:378033-379145:+ | gene-YGL063W_NCYC1407 | rna-NM_001180928.4_NCYC1407 | cds-NP_011452.4_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:379687-380799:+ | gene-YGL063W_PE2H3 | rna-NM_001180928.4_PE2H3 | cds-NP_011452.4_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:384737-385849:+ | gene-YGL063W_PE2H4 | rna-NM_001180928.4_PE2H4 | cds-NP_011452.4_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:383654-384766:+ | gene-YGL063W_S288C | rna-NM_001180928.4_S288C | cds-NP_011452.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000096.1:18822-19934:+ | gene-YGL063W_SA1 | rna-NM_001180928.4_SA1 | cds-NP_011452.4_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:378530-379642:+ | gene-YGL063W_ThermosaccDry | rna-NM_001180928.4_ThermosaccDry | cds-NP_011452.4_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:488914-490026:+ | gene-YGL063W_VR1 | rna-NM_001180928.4_VR1 | cds-NP_011452.4_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:375894-377006:+ | gene-YGL063W_ZTW1 | rna-NM_001180928.4_ZTW1 | cds-NP_011452.4_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:381520-382631:+ | gene-YGL063W_Sparadoxus | rna-NM_001180928.4_Sparadoxus | cds-NP_011452.4_Sparadoxus | 90.1 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |