Gene name: PUS1
Reference locus (S288C): YPL212C
Gene biotype: protein_coding
Description: tRNA:pseudouridine synthase; introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; also acts on U2 snRNA; also pseudouridylates some mRNAs, and pseudouridylation level varies with growth phase; nuclear protein that appears to be involved in tRNA export; PUS1 has a paralog, PUS2, that arose from the whole genome duplication
Top 10 interactors (score): PUS4 (0.99); PUS7 (0.986); PUS9 (0.952); PUS6 (0.945); CBF5 (0.933); TRM82 (0.931); NCL1 (0.93); PUS5 (0.93); TRM1 (0.927); TRM10 (0.923); TRM7 (0.916); RIB2 (0.904); LOS1 (0.896); NHP2 (0.877); SMM1 (0.87); DUS3 (0.861); TAN1 (0.861); MTO1 (0.836); TRM5 (0.82); MRM2 (0.811)
Homologues (species, bitscore): PUS1 (Homo sapiens, 213.4); Pus1 (Mus musculus, 201.4); pus1 (Danio rerio, 199.5); pus1 (Xenopus tropicalis, 211.5); CG4159 (Drosophila melanogaster, 193.0); pus-1 (Caenorhabditis elegans, 144.1); AT1G20370 (Arabidopsis thaliana, 185.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:129387-131021:- | gene-YPL212C_AKU4011 | rna-NM_001184026.1_AKU4011 | cds-NP_015112.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:335158-336792:- | gene-YPL212C_BG1 | rna-NM_001184026.1_BG1 | cds-NP_015112.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:154852-156486:- | gene-YPL212C_Bruggeman | rna-NM_001184026.1_Bruggeman | cds-NP_015112.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:151460-153094:- | gene-YPL212C_CAT1 | rna-NM_001184026.1_CAT1 | cds-NP_015112.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:133573-135207:- | gene-YPL212C_CBS1585 | rna-NM_001184026.1_CBS1585 | cds-NP_015112.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:147996-149630:- | gene-YPL212C_CBS436 | rna-NM_001184026.1_CBS436 | cds-NP_015112.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:138376-140010:- | gene-YPL212C_CBS6412 | rna-NM_001184026.1_CBS6412 | cds-NP_015112.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:129750-131384:- | gene-YPL212C_CBS6413 | rna-NM_001184026.1_CBS6413 | cds-NP_015112.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:151452-153086:- | gene-YPL212C_CENPK1137D | rna-NM_001184026.1_CENPK1137D | cds-NP_015112.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:128503-130137:- | gene-YPL212C_EthanolRed | rna-NM_001184026.1_EthanolRed | cds-NP_015112.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:135709-137343:- | gene-YPL212C_FaliES1 | rna-NM_001184026.1_FaliES1 | cds-NP_015112.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000069.1:20982-22616:+ | gene-YPL212C_JAY291 | rna-NM_001184026.1_JAY291 | cds-NP_015112.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:146561-148195:- | gene-YPL212C_MUCL30387 | rna-NM_001184026.1_MUCL30387 | cds-NP_015112.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:144752-146386:- | gene-YPL212C_MUCL30388 | rna-NM_001184026.1_MUCL30388 | cds-NP_015112.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:126703-128337:- | gene-YPL212C_MUCL39482 | rna-NM_001184026.1_MUCL39482 | cds-NP_015112.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:145586-147220:- | gene-YPL212C_MUCL42920 | rna-NM_001184026.1_MUCL42920 | cds-NP_015112.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:151498-153132:- | gene-YPL212C_NCIM3186 | rna-NM_001184026.1_NCIM3186 | cds-NP_015112.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:133151-134785:- | gene-YPL212C_NCYC1407 | rna-NM_001184026.1_NCYC1407 | cds-NP_015112.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:140858-142492:- | gene-YPL212C_PE2H3 | rna-NM_001184026.1_PE2H3 | cds-NP_015112.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:140501-142135:- | gene-YPL212C_PE2H4 | rna-NM_001184026.1_PE2H4 | cds-NP_015112.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:151515-153149:- | gene-YPL212C_S288C | rna-NM_001184026.1_S288C | cds-NP_015112.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000095.1:21032-22666:+ | gene-YPL212C_SA1 | rna-NM_001184026.1_SA1 | cds-NP_015112.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:135490-137124:- | gene-YPL212C_ThermosaccDry | rna-NM_001184026.1_ThermosaccDry | cds-NP_015112.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:149539-151173:- | gene-YPL212C_VR1 | rna-NM_001184026.1_VR1 | cds-NP_015112.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:135010-136644:- | gene-YPL212C_ZTW1 | rna-NM_001184026.1_ZTW1 | cds-NP_015112.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:136582-138231:- | gene-YPL212C_Sparadoxus | rna-NM_001184026.1_Sparadoxus | cds-NP_015112.1_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |