Gene name: PUP2
Reference locus (S288C): YGR253C
Gene biotype: protein_coding
Description: Alpha 5 subunit of the 20S proteasome; involved in ubiquitin-dependent catabolism; human homolog is subunit zeta; Belongs to the peptidase T1A family
Top 10 interactors (score): ADD66 (0.999); SCL1 (0.999); RPT2 (0.999); RPN1 (0.999); PRE5 (0.999); RPN11 (0.999); RPN10 (0.999); PRE6 (0.999); PRE9 (0.999); BLM10 (0.999); RPN7 (0.999); PRE3 (0.999); UBP6 (0.999); RPN9 (0.999); RPT5 (0.999); RPN8 (0.999); PUP1 (0.999); RPN5 (0.999); RPN12 (0.999); PRE2 (0.999)
Homologues (species, bitscore): PSMA5 (Homo sapiens, 289.3); Psma5 (Mus musculus, 289.3); psma5 (Danio rerio, 286.6); psma5 (Xenopus tropicalis, 197.2); Prosalpha5 (Drosophila melanogaster, 276.6); pas-5 (Caenorhabditis elegans, 247.3); PAE2 (Arabidopsis thaliana, 303.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:963786-964568:- | gene-YGR253C_AKU4011 | rna-NM_001181382.1_AKU4011 | cds-NP_011769.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:243956-244738:- | gene-YGR253C_BG1 | rna-NM_001181382.1_BG1 | cds-NP_011769.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:972304-973086:- | gene-YGR253C_Bruggeman | rna-NM_001181382.1_Bruggeman | cds-NP_011769.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:971241-972023:- | gene-YGR253C_CAT1 | rna-NM_001181382.1_CAT1 | cds-NP_011769.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:966657-967439:- | gene-YGR253C_CBS1585 | rna-NM_001181382.1_CBS1585 | cds-NP_011769.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:970286-971068:- | gene-YGR253C_CBS436 | rna-NM_001181382.1_CBS436 | cds-NP_011769.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:957546-958328:- | gene-YGR253C_CBS6412 | rna-NM_001181382.1_CBS6412 | cds-NP_011769.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:963601-964383:- | gene-YGR253C_CBS6413 | rna-NM_001181382.1_CBS6413 | cds-NP_011769.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:998040-998822:- | gene-YGR253C_CENPK1137D | rna-NM_001181382.1_CENPK1137D | cds-NP_011769.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:951638-952420:- | gene-YGR253C_EthanolRed | rna-NM_001181382.1_EthanolRed | cds-NP_011769.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:956444-957226:- | gene-YGR253C_FaliES1 | rna-NM_001181382.1_FaliES1 | cds-NP_011769.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:73086-73868:+ | gene-YGR253C_JAY291 | rna-NM_001181382.1_JAY291 | cds-NP_011769.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:970041-970823:- | gene-YGR253C_MUCL30387 | rna-NM_001181382.1_MUCL30387 | cds-NP_011769.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:968173-968955:- | gene-YGR253C_MUCL30388 | rna-NM_001181382.1_MUCL30388 | cds-NP_011769.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:961762-962544:- | gene-YGR253C_MUCL39482 | rna-NM_001181382.1_MUCL39482 | cds-NP_011769.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:979637-980419:- | gene-YGR253C_MUCL42920 | rna-NM_001181382.1_MUCL42920 | cds-NP_011769.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:998358-999140:- | gene-YGR253C_NCIM3186 | rna-NM_001181382.1_NCIM3186 | cds-NP_011769.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:957391-958173:- | gene-YGR253C_NCYC1407 | rna-NM_001181382.1_NCYC1407 | cds-NP_011769.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:982581-983363:- | gene-YGR253C_PE2H3 | rna-NM_001181382.1_PE2H3 | cds-NP_011769.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:987420-988202:- | gene-YGR253C_PE2H4 | rna-NM_001181382.1_PE2H4 | cds-NP_011769.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:998358-999140:- | gene-YGR253C_S288C | rna-NM_001181382.1_S288C | cds-NP_011769.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000045.1:2277-3059:+ | gene-YGR253C_SA1 | rna-NM_001181382.1_SA1 | cds-NP_011769.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:976964-977746:- | gene-YGR253C_ThermosaccDry | rna-NM_001181382.1_ThermosaccDry | cds-NP_011769.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1082742-1083524:- | gene-YGR253C_VR1 | rna-NM_001181382.1_VR1 | cds-NP_011769.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:278376-279158:- | gene-YGR253C_ZTW1 | rna-NM_001181382.1_ZTW1 | cds-NP_011769.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:968979-969761:- | gene-YGR253C_Sparadoxus | rna-NM_001181382.1_Sparadoxus | cds-NP_011769.1_Sparadoxus | 92.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |