PUP1 (YOR157C)


Gene profile

Gene name: PUP1
Reference locus (S288C): YOR157C
Gene biotype: protein_coding

Description: Beta 2 subunit of the 20S proteasome; endopeptidase with trypsin-like activity that cleaves after basic residues; synthesized as a proprotein before being proteolytically processed for assembly into 20S particle; human homolog is subunit Z

Top 10 interactors (score): PRE8 (0.999); RPN13 (0.999); PRE7 (0.999); PRE1 (0.999); PUP3 (0.999); RPT4 (0.999); PRE4 (0.999); RPT3 (0.999); RPN3 (0.999); RPT6 (0.999); PRE10 (0.999); RPT1 (0.999); PRE9 (0.999); SCL1 (0.999); RPT2 (0.999); PRE5 (0.999); RPN1 (0.999); RPN6 (0.999); RPN2 (0.999); UMP1 (0.999)

Homologues (species, bitscore): PSMB7 (Homo sapiens, 289.3); Psmb7 (Mus musculus, 290.0); psmb7 (Danio rerio, 280.4); psmb7 (Xenopus tropicalis, 284.3); Prosbeta2 (Drosophila melanogaster, 288.9); pbs-2 (Caenorhabditis elegans, 207.2); PBB2 (Arabidopsis thaliana, 276.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:628602-629387:- gene-YOR157C_AKU4011 rna-NM_001183576.3_AKU4011 cds-NP_014800.3_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:30359-31144:- gene-YOR157C_BG1 rna-NM_001183576.3_BG1 cds-NP_014800.3_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:612676-613461:- gene-YOR157C_Bruggeman rna-NM_001183576.3_Bruggeman cds-NP_014800.3_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:612694-613479:- gene-YOR157C_CAT1 rna-NM_001183576.3_CAT1 cds-NP_014800.3_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:611097-611882:- gene-YOR157C_CBS1585 rna-NM_001183576.3_CBS1585 cds-NP_014800.3_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:609392-610177:- gene-YOR157C_CBS436 rna-NM_001183576.3_CBS436 cds-NP_014800.3_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:608709-609494:- gene-YOR157C_CBS6412 rna-NM_001183576.3_CBS6412 cds-NP_014800.3_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:617390-618175:- gene-YOR157C_CBS6413 rna-NM_001183576.3_CBS6413 cds-NP_014800.3_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:630725-631510:- gene-YOR157C_CENPK1137D rna-NM_001183576.3_CENPK1137D cds-NP_014800.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:604805-605590:- gene-YOR157C_EthanolRed rna-NM_001183576.3_EthanolRed cds-NP_014800.3_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:609658-610443:- gene-YOR157C_FaliES1 rna-NM_001183576.3_FaliES1 cds-NP_014800.3_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000070.1:33095-33880:+ gene-YOR157C_JAY291 rna-NM_001183576.3_JAY291 cds-NP_014800.3_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:617483-618268:- gene-YOR157C_MUCL30387 rna-NM_001183576.3_MUCL30387 cds-NP_014800.3_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:624246-625031:- gene-YOR157C_MUCL30388 rna-NM_001183576.3_MUCL30388 cds-NP_014800.3_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:618938-619723:- gene-YOR157C_MUCL39482 rna-NM_001183576.3_MUCL39482 cds-NP_014800.3_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:628360-629145:- gene-YOR157C_MUCL42920 rna-NM_001183576.3_MUCL42920 cds-NP_014800.3_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:630855-631640:- gene-YOR157C_NCIM3186 rna-NM_001183576.3_NCIM3186 cds-NP_014800.3_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:619024-619809:- gene-YOR157C_NCYC1407 rna-NM_001183576.3_NCYC1407 cds-NP_014800.3_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:617536-618321:- gene-YOR157C_PE2H3 rna-NM_001183576.3_PE2H3 cds-NP_014800.3_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:627913-628698:- gene-YOR157C_PE2H4 rna-NM_001183576.3_PE2H4 cds-NP_014800.3_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:630966-631751:- gene-YOR157C_S288C rna-NM_001183576.3_S288C cds-NP_014800.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:47522-48307:- gene-YOR157C_SA1 rna-NM_001183576.3_SA1 cds-NP_014800.3_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:608841-609626:- gene-YOR157C_ThermosaccDry rna-NM_001183576.3_ThermosaccDry cds-NP_014800.3_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:672539-673324:- gene-YOR157C_VR1 rna-NM_001183576.3_VR1 cds-NP_014800.3_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:342291-343076:- gene-YOR157C_ZTW1 rna-NM_001183576.3_ZTW1 cds-NP_014800.3_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:613978-614763:- gene-YOR157C_Sparadoxus rna-NM_001183576.3_Sparadoxus cds-NP_014800.3_Sparadoxus 93.3 100.0 Verified 1 1 1 False True False False False

Additional files