Gene name: PUF6
Reference locus (S288C): YDR496C
Gene biotype: protein_coding
Description: Pumilio-homology domain protein; binds the 3' UTR of ASH1 mRNA and represses its translation, resulting in proper asymmetric localization of ASH1 mRNA; required at post-transcriptional step for efficient retrotransposition; absence results in decreased Ty1 Gag:GFP protein levels; co-sediments with the 60S ribosomal subunit and is required for its biogenesis; Belongs to the PUF6 family
Top 10 interactors (score): NOP2 (0.999); FUN12 (0.999); NOP15 (0.999); HAS1 (0.999); NOG2 (0.999); NSA2 (0.999); NOP12 (0.999); DRS1 (0.999); RLP24 (0.999); NMD3 (0.999); NOP9 (0.999); DBP10 (0.999); MAK21 (0.999); CIC1 (0.999); NOG1 (0.999); NOP4 (0.999); DBP3 (0.999); BRX1 (0.999); NOC2 (0.999); MAK16 (0.999)
Homologues (species, bitscore): KIAA0020 (Homo sapiens, 173.7); Pum3 (Mus musculus, 178.3); im:7148292 (Danio rerio, 175.6); kiaa0020 (Xenopus tropicalis, 181.4); pen (Drosophila melanogaster, 142.5); puf-12 (Caenorhabditis elegans, 168.3); PUM24 (Arabidopsis thaliana, 164.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1381418-1383388:- | gene-YDR496C_AKU4011 | rna-NM_001180804.1_AKU4011 | cds-NP_010784.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000073.1:22972-24942:- | gene-YDR496C_BG1 | rna-NM_001180804.1_BG1 | cds-NP_010784.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1412764-1414734:- | gene-YDR496C_Bruggeman | rna-NM_001180804.1_Bruggeman | cds-NP_010784.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1389918-1391888:- | gene-YDR496C_CAT1 | rna-NM_001180804.1_CAT1 | cds-NP_010784.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1375660-1377630:- | gene-YDR496C_CBS1585 | rna-NM_001180804.1_CBS1585 | cds-NP_010784.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1395013-1396983:- | gene-YDR496C_CBS436 | rna-NM_001180804.1_CBS436 | cds-NP_010784.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1371302-1373272:- | gene-YDR496C_CBS6412 | rna-NM_001180804.1_CBS6412 | cds-NP_010784.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1394317-1396287:- | gene-YDR496C_CBS6413 | rna-NM_001180804.1_CBS6413 | cds-NP_010784.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1440128-1442098:- | gene-YDR496C_CENPK1137D | rna-NM_001180804.1_CENPK1137D | cds-NP_010784.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1384709-1386679:- | gene-YDR496C_EthanolRed | rna-NM_001180804.1_EthanolRed | cds-NP_010784.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1388262-1390232:- | gene-YDR496C_FaliES1 | rna-NM_001180804.1_FaliES1 | cds-NP_010784.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:86507-88477:- | gene-YDR496C_JAY291 | rna-NM_001180804.1_JAY291 | cds-NP_010784.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1395262-1397232:- | gene-YDR496C_MUCL30387 | rna-NM_001180804.1_MUCL30387 | cds-NP_010784.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1377282-1379252:- | gene-YDR496C_MUCL30388 | rna-NM_001180804.1_MUCL30388 | cds-NP_010784.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1367145-1369115:- | gene-YDR496C_MUCL39482 | rna-NM_001180804.1_MUCL39482 | cds-NP_010784.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1309935-1311905:- | gene-YDR496C_MUCL42920 | rna-NM_001180804.1_MUCL42920 | cds-NP_010784.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1441356-1443326:- | gene-YDR496C_NCIM3186 | rna-NM_001180804.1_NCIM3186 | cds-NP_010784.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1380931-1382901:- | gene-YDR496C_NCYC1407 | rna-NM_001180804.1_NCYC1407 | cds-NP_010784.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1391776-1393746:- | gene-YDR496C_PE2H3 | rna-NM_001180804.1_PE2H3 | cds-NP_010784.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1397348-1399318:- | gene-YDR496C_PE2H4 | rna-NM_001180804.1_PE2H4 | cds-NP_010784.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1441433-1443403:- | gene-YDR496C_S288C | rna-NM_001180804.1_S288C | cds-NP_010784.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:173734-175704:+ | gene-YDR496C_SA1 | rna-NM_001180804.1_SA1 | cds-NP_010784.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1392484-1394454:- | gene-YDR496C_ThermosaccDry | rna-NM_001180804.1_ThermosaccDry | cds-NP_010784.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1408219-1410189:- | gene-YDR496C_VR1 | rna-NM_001180804.1_VR1 | cds-NP_010784.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:435150-437120:- | gene-YDR496C_ZTW1 | rna-NM_001180804.1_ZTW1 | cds-NP_010784.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1395289-1397259:- | gene-YDR496C_Sparadoxus | rna-NM_001180804.1_Sparadoxus | cds-NP_010784.1_Sparadoxus | 90.8 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |