PUF2 (YPR042C)


Gene profile

Gene name: PUF2
Reference locus (S288C): YPR042C
Gene biotype: protein_coding

Description: PUF family mRNA-binding protein; Pumilio homology domain confers RNA binding activity; preferentially binds mRNAs encoding membrane-associated proteins; binding site composed of two UAAU tetranucleotides, separated by a 3-nt linker; PUF2 has a paralog, JSN1, that arose from the whole genome duplication

Top 10 interactors (score): WHI3 (0.914); MRN1 (0.91); PUF6 (0.874); PUB1 (0.847); YLL032C (0.842); HEK2 (0.828); YBL081W (0.82); SHE2 (0.81); NSP1 (0.792); NAM8 (0.783); YBR016W (0.783); SCP160 (0.781); SDD4 (0.769); MUD1 (0.764); NOT3 (0.751); NRP1 (0.729); POP2 (0.723); COX17 (0.715); CDC33 (0.712); SUP35 (0.698)

Homologues (species, bitscore): PUM1 (Homo sapiens, 61.6); Pum1 (Mus musculus, 63.5); pum1 (Danio rerio, 59.7); pum2 (Xenopus tropicalis, 58.9); pum (Drosophila melanogaster, 53.9); puf-9 (Caenorhabditis elegans, 64.7); PUM9 (Arabidopsis thaliana, 72.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:622118-625321:- gene-YPR042C_AKU4011 rna-NM_001184139.1_AKU4011 cds-NP_015367.1_AKU4011 98.8 99.2 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:272339-275567:+ gene-YPR042C_BG1 rna-NM_001184139.1_BG1 cds-NP_015367.1_BG1 99.3 99.9 Unannotated 1 1 0 False False False True False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:699757-702987:- gene-YPR042C_Bruggeman rna-NM_001184139.1_Bruggeman cds-NP_015367.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:743191-746443:- gene-YPR042C_CAT1 rna-NM_001184139.1_CAT1 cds-NP_015367.1_CAT1 99.1 100.0 Unannotated 1 1 0 False False False True False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:625802-629005:- gene-YPR042C_CBS1585 rna-NM_001184139.1_CBS1585 cds-NP_015367.1_CBS1585 98.8 99.2 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:640168-643392:- gene-YPR042C_CBS436 rna-NM_001184139.1_CBS436 cds-NP_015367.1_CBS436 99.7 99.9 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:629550-632753:- gene-YPR042C_CBS6412 rna-NM_001184139.1_CBS6412 cds-NP_015367.1_CBS6412 98.8 99.2 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:622751-625954:- gene-YPR042C_CBS6413 rna-NM_001184139.1_CBS6413 cds-NP_015367.1_CBS6413 98.8 99.2 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:650407-653634:- gene-YPR042C_CENPK1137D rna-NM_001184139.1_CENPK1137D cds-NP_015367.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:949296-952508:- gene-YPR042C_EthanolRed rna-NM_001184139.1_EthanolRed cds-NP_015367.1_EthanolRed 98.5 99.4 Verified 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:627842-631147:- gene-YPR042C_FaliES1 rna-NM_001184139.1_FaliES1 cds-NP_015367.1_FaliES1 97.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000446.1:1-3114:- gene-YPR042C_JAY291 rna-NM_001184139.1_JAY291 cds-NP_015367.1_JAY291 96.4 96.4 Verified 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:640969-644249:- gene-YPR042C_MUCL30387 rna-NM_001184139.1_MUCL30387 cds-NP_015367.1_MUCL30387 98.3 100.0 Verified 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:639664-642953:- gene-YPR042C_MUCL30388 rna-NM_001184139.1_MUCL30388 cds-NP_015367.1_MUCL30388 98.1 100.0 Verified 1 1 0 False False False True False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:619059-622262:- gene-YPR042C_MUCL39482 rna-NM_001184139.1_MUCL39482 cds-NP_015367.1_MUCL39482 98.8 99.2 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:681860-685090:- gene-YPR042C_MUCL42920 rna-NM_001184139.1_MUCL42920 cds-NP_015367.1_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:650418-653645:- gene-YPR042C_NCIM3186 rna-NM_001184139.1_NCIM3186 cds-NP_015367.1_NCIM3186 99.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:626991-630194:- gene-YPR042C_NCYC1407 rna-NM_001184139.1_NCYC1407 cds-NP_015367.1_NCYC1407 98.7 99.2 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:633199-636417:- gene-YPR042C_PE2H3 rna-NM_001184139.1_PE2H3 cds-NP_015367.1_PE2H3 99.6 99.7 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:632847-636065:- gene-YPR042C_PE2H4 rna-NM_001184139.1_PE2H4 cds-NP_015367.1_PE2H4 99.6 99.7 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:650435-653662:- gene-YPR042C_S288C rna-NM_001184139.1_S288C cds-NP_015367.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000026.1:47113-50334:+ gene-YPR042C_SA1 rna-NM_001184139.1_SA1 cds-NP_015367.1_SA1 99.8 99.8 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:627642-630922:- gene-YPR042C_ThermosaccDry rna-NM_001184139.1_ThermosaccDry cds-NP_015367.1_ThermosaccDry 98.0 100.0 Verified 1 1 0 False False False True False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:643861-647088:- gene-YPR042C_VR1 rna-NM_001184139.1_VR1 cds-NP_015367.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:626959-630162:- gene-YPR042C_ZTW1 rna-NM_001184139.1_ZTW1 cds-NP_015367.1_ZTW1 98.8 99.2 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:627744-630953:- gene-YPR042C_Sparadoxus rna-NM_001184139.1_Sparadoxus cds-NP_015367.1_Sparadoxus 88.0 98.8 Verified 1 1 1 False True False False False

Additional files