Gene name: PUB1
Reference locus (S288C): YNL016W
Gene biotype: protein_coding
Description: Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1; Poly (A)+ RNA-binding protein; abundant mRNP-component protein that binds mRNA and is required for stability of many mRNAs; component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly; implicated in regulation of translation; carries Q/N-rich domain at C- terminus, identified as candidate prion; human homolog Tia1 is critical for normal synaptic plasticity; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): TIF4632 (0.974); TIF4631 (0.958); NPL3 (0.923); SUP35 (0.916); NAM7 (0.881); CDC33 (0.875); PUF4 (0.866); HEK2 (0.865); PUF3 (0.861); PUF2 (0.847); EDC3 (0.846); PBP1 (0.837); PAB1 (0.835); DHH1 (0.832); SGN1 (0.826); NRP1 (0.823); NRD1 (0.818); MRN1 (0.817); NAB3 (0.815); WHI3 (0.815)
Homologues (species, bitscore): TIA1 (Homo sapiens, 159.1); Tia1 (Mus musculus, 159.8); tia1l (Danio rerio, 158.3); tial1 (Xenopus tropicalis, 157.5); Rox8 (Drosophila melanogaster, 135.6); tiar-1 (Caenorhabditis elegans, 145.6); UBP1A (Arabidopsis thaliana, 154.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:585839-587200:+ | gene-YNL016W_AKU4011 | rna-NM_001182855.1_AKU4011 | cds-NP_014382.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:488342-489703:+ | gene-YNL016W_BG1 | rna-NM_001182855.1_BG1 | cds-NP_014382.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:602794-604158:+ | gene-YNL016W_Bruggeman | rna-NM_001182855.1_Bruggeman | cds-NP_014382.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:638167-639528:+ | gene-YNL016W_CAT1 | rna-NM_001182855.1_CAT1 | cds-NP_014382.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:591525-592886:+ | gene-YNL016W_CBS1585 | rna-NM_001182855.1_CBS1585 | cds-NP_014382.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:653667-655028:+ | gene-YNL016W_CBS436 | rna-NM_001182855.1_CBS436 | cds-NP_014382.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:581329-582690:+ | gene-YNL016W_CBS6412 | rna-NM_001182855.1_CBS6412 | cds-NP_014382.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:582548-583909:+ | gene-YNL016W_CBS6413 | rna-NM_001182855.1_CBS6413 | cds-NP_014382.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:596554-597915:+ | gene-YNL016W_CENPK1137D | rna-NM_001182855.1_CENPK1137D | cds-NP_014382.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:587948-589309:+ | gene-YNL016W_EthanolRed | rna-NM_001182855.1_EthanolRed | cds-NP_014382.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:578719-580080:+ | gene-YNL016W_FaliES1 | rna-NM_001182855.1_FaliES1 | cds-NP_014382.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000008.1:27848-29209:- | gene-YNL016W_JAY291 | rna-NM_001182855.1_JAY291 | cds-NP_014382.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:600883-602247:+ | gene-YNL016W_MUCL30387 | rna-NM_001182855.1_MUCL30387 | cds-NP_014382.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:606536-607897:- | gene-YNL016W_MUCL30388 | rna-NM_001182855.1_MUCL30388 | cds-NP_014382.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:583080-584441:+ | gene-YNL016W_MUCL39482 | rna-NM_001182855.1_MUCL39482 | cds-NP_014382.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:586976-588340:+ | gene-YNL016W_MUCL42920 | rna-NM_001182855.1_MUCL42920 | cds-NP_014382.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:602876-604237:+ | gene-YNL016W_NCIM3186 | rna-NM_001182855.1_NCIM3186 | cds-NP_014382.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:585325-586686:+ | gene-YNL016W_NCYC1407 | rna-NM_001182855.1_NCYC1407 | cds-NP_014382.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:587365-588726:+ | gene-YNL016W_PE2H3 | rna-NM_001182855.1_PE2H3 | cds-NP_014382.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:588683-590044:+ | gene-YNL016W_PE2H4 | rna-NM_001182855.1_PE2H4 | cds-NP_014382.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:602907-604268:+ | gene-YNL016W_S288C | rna-NM_001182855.1_S288C | cds-NP_014382.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000068.1:579-1940:+ | gene-YNL016W_SA1 | rna-NM_001182855.1_SA1 | cds-NP_014382.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:579061-580422:+ | gene-YNL016W_ThermosaccDry | rna-NM_001182855.1_ThermosaccDry | cds-NP_014382.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:621711-623072:+ | gene-YNL016W_VR1 | rna-NM_001182855.1_VR1 | cds-NP_014382.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:487942-489306:+ | gene-YNL016W_ZTW1 | rna-NM_001182855.1_ZTW1 | cds-NP_014382.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:594196-595560:+ | gene-YNL016W_Sparadoxus | rna-NM_001182855.1_Sparadoxus | cds-NP_014382.1_Sparadoxus | 92.8 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |