PTP3 (YER075C)


Gene profile

Gene name: PTP3
Reference locus (S288C): YER075C
Gene biotype: protein_coding

Description: Tyrosine-protein phosphatase 3; Phosphotyrosine-specific protein phosphatase; involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm

Top 10 interactors (score): HOG1 (0.999); PBS2 (0.992); FUS3 (0.988); SLT2 (0.985); PTP2 (0.975); KSS1 (0.972); PTC1 (0.91); PTC2 (0.893); SSK1 (0.877); SSK2 (0.866); SSK22 (0.864); MSG5 (0.853); PTC3 (0.844); SKO1 (0.835); YVH1 (0.827); PTP1 (0.824); STE7 (0.816); YPD1 (0.814); YCH1 (0.789); STE11 (0.765)

Homologues (species, bitscore): PTPN18 (Homo sapiens, 105.1); Ptprz1 (Mus musculus, 94.7); ptpreb (Danio rerio, 100.5); ptpn21 (Xenopus tropicalis, 96.7); Ptp52F (Drosophila melanogaster, 89.4); Y41D4A.5 (Caenorhabditis elegans, 96.7); PTP1 (Arabidopsis thaliana, 95.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:302196-304985:- gene-YER075C_AKU4011 rna-NM_001178966.2_AKU4011 cds-NP_010998.2_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:120822-123608:+ gene-YER075C_BG1 rna-NM_001178966.2_BG1 cds-NP_010998.2_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:311784-314570:- gene-YER075C_Bruggeman rna-NM_001178966.2_Bruggeman cds-NP_010998.2_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:305637-308432:- gene-YER075C_CAT1 rna-NM_001178966.2_CAT1 cds-NP_010998.2_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:302051-304849:- gene-YER075C_CBS1585 rna-NM_001178966.2_CBS1585 cds-NP_010998.2_CBS1585 98.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:304194-306980:- gene-YER075C_CBS436 rna-NM_001178966.2_CBS436 cds-NP_010998.2_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:301518-304307:- gene-YER075C_CBS6412 rna-NM_001178966.2_CBS6412 cds-NP_010998.2_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:307501-310296:- gene-YER075C_CBS6413 rna-NM_001178966.2_CBS6413 cds-NP_010998.2_CBS6413 98.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:306200-308989:- gene-YER075C_CENPK1137D rna-NM_001178966.2_CENPK1137D cds-NP_010998.2_CENPK1137D 99.3 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:302530-305328:- gene-YER075C_EthanolRed rna-NM_001178966.2_EthanolRed cds-NP_010998.2_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:302975-305773:- gene-YER075C_FaliES1 rna-NM_001178966.2_FaliES1 cds-NP_010998.2_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000153.1:18038-20824:- gene-YER075C_JAY291 rna-NM_001178966.2_JAY291 cds-NP_010998.2_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:307180-309965:- gene-YER075C_MUCL30387 rna-NM_001178966.2_MUCL30387 cds-NP_010998.2_MUCL30387 99.8 99.9 Unannotated 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:302851-305636:- gene-YER075C_MUCL30388 rna-NM_001178966.2_MUCL30388 cds-NP_010998.2_MUCL30388 99.8 99.9 Unannotated 1 1 0 False False False True False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:301078-303873:- gene-YER075C_MUCL39482 rna-NM_001178966.2_MUCL39482 cds-NP_010998.2_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:308319-311105:- gene-YER075C_MUCL42920 rna-NM_001178966.2_MUCL42920 cds-NP_010998.2_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:308412-311198:- gene-YER075C_NCIM3186 rna-NM_001178966.2_NCIM3186 cds-NP_010998.2_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:306148-308938:- gene-YER075C_NCYC1407 rna-NM_001178966.2_NCYC1407 cds-NP_010998.2_NCYC1407 99.1 100.0 Unannotated 1 1 0 False False False True False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:316791-319577:- gene-YER075C_PE2H3 rna-NM_001178966.2_PE2H3 cds-NP_010998.2_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:306732-309518:- gene-YER075C_PE2H4 rna-NM_001178966.2_PE2H4 cds-NP_010998.2_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:308413-311199:- gene-YER075C_S288C rna-NM_001178966.2_S288C cds-NP_010998.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000023.1:18051-20837:- gene-YER075C_SA1 rna-NM_001178966.2_SA1 cds-NP_010998.2_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:303772-306570:- gene-YER075C_ThermosaccDry rna-NM_001178966.2_ThermosaccDry cds-NP_010998.2_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:304472-307258:- gene-YER075C_VR1 rna-NM_001178966.2_VR1 cds-NP_010998.2_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:300943-303729:- gene-YER075C_ZTW1 rna-NM_001178966.2_ZTW1 cds-NP_010998.2_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:304355-307099:- gene-YER075C_Sparadoxus rna-NM_001178966.2_Sparadoxus cds-NP_010998.2_Sparadoxus 87.2 98.4 Verified 1 1 1 False True False False False

Additional files